New insights into the antidepressant actions of substance P (NK1 receptor) antagonists (Q34132678)

31 July 2017

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title

New insights into the antidepressant actions of substance P (NK1 receptor) antagonists (English)

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31 July 2017

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Nadia M J Rupniak

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31 July 2017

publication date

1 May 2002

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Canadian Journal of Physiology and Pharmacology

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published in

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volume

80

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issue

5

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page(s)

489-494

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Effects of microinjections of the neuropeptide substance P in the dorsal periaqueductal gray on the behaviour of rats in the plus-maze test.

31 July 2017

cites work

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Distribution, morphology and number of monoamine-synthesizing and substance P-containing neurons in the human dorsal raphe nucleus

21 January 2018

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Inhibition of shock-induced foot tapping behaviour in the gerbil by a tachykinin NK1 receptor antagonist

21 January 2018

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Role of endogenous substance P in stress-induced activation of mesocortical dopamine neurones

21 January 2018

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Mild footshock stress dissociates substance P from substance K and dynorphin from Met- and Leu-enkephalin

21 January 2018

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Affinities of venlafaxine and various reuptake inhibitors for the serotonin and norepinephrine transporters.

21 January 2018

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Investigation into species variants in tachykinin NK1 receptors by use of the non-peptide antagonist, CP-96,345

21 January 2018

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CSF substance P immunoreactivity in affective disorders

21 January 2018

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Intra-amygdala injection of the substance P [NK(1) receptor] antagonist L-760735 inhibits neonatal vocalisations in guinea-pigs

21 January 2018

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Substance P excitation of rat locus coeruleus neurones

21 January 2018

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Anxiolytic actions of the substance P (NK1) receptor antagonist L-760735 and the 5-HT1A agonist 8-OH-DPAT in the social interaction test in gerbils.

21 January 2018

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Altered nociception, analgesia and aggression in mice lacking the receptor for substance P

21 January 2018

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Chronic fluoxetine in tests of anxiety in rat lines selectively bred for differential 5-HT1A receptor function

21 January 2018

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GR205171: a novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity

21 January 2018

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Species differences in affinities of non-peptide antagonists for substance p receptors

21 January 2018

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Excitation of neurons in the nucleus locus coeruleus by substance P and related peptides

21 January 2018

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Distribution of substance P-like immunoreactive neurons in the human medulla oblongata: co-localization with monoamine-synthesizing neurons

21 January 2018

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Substance P is involved in the sensitization of the acoustic startle response by footshocks in rats

21 January 2018

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Substance P receptors: Localization by light microscopic autoradiography in rat brain using [3H]SP as the radioligand

21 January 2018

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Chronic substance P (NK1) receptor antagonist and conventional antidepressant treatment increases burst firing of monoamine neurones in the locus coeruleus

21 January 2018

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Selective blockade of neurokinin (NK)(1) receptors facilitates the activity of adrenergic pathways projecting to frontal cortex and dorsal hippocampus in rats

21 January 2018

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Electron microscopic localization of substance P and enkephalin in axon terminals related to dendrites of catecholaminergic neurons

21 January 2018

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Pharmacological blockade or genetic deletion of substance P (NK(1)) receptors attenuates neonatal vocalisation in guinea-pigs and mice.

21 January 2018

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Comparison of the phenotype of NK1R-/- mice with pharmacological blockade of the substance P (NK1 ) receptor in assays for antidepressant and anxiolytic drugs

21 January 2018

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Differential localization of 3H-[Pro9]SP binding sites in the guinea pig and rat brain

21 January 2018

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Evidence that substance P is utilized in medial amygdaloid facilitation of defensive rage behavior in the cat.

21 January 2018

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A comparison of the anatomical distribution of substance P and substance P receptors in the rat central nervous system

21 January 2018

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Acute and chronic effects of gepirone and fluoxetine in rats tested in the elevated plus-maze: an ethological analysis.

21 January 2018

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Adverse reactions of selective serotonin reuptake inhibitors: reports from a spontaneous reporting system

21 January 2018

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Effect of immobilization stress on neuropeptides and their receptors in rat central nervous system

21 January 2018

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Substance P induces a cardiovascular defense reaction in the rat: pharmacological characterization

21 January 2018

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Substance P (NK1) receptors in the cingulate cortex in unipolar and bipolar mood disorder and schizophrenia

21 January 2018

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Stress-induced C-fos expression in the rat locus coeruleus is dependent on neurokinin 1 receptor activation

21 January 2018

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The NK1-receptor antagonist NKP608 has an antidepressant-like effect in the chronic mild stress model of depression in rats

21 January 2018

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Serotonin and substance P co-exist in dorsal raphe neurons of the human brain

21 January 2018

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Responsiveness of mesolimbic, mesocortical, septal and hippocampal cholecystokinin and substance P neuronal systems to stress, in the male rat

21 January 2018

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The substance P antagonist L-760,735 inhibits stress-induced NK(1) receptor internalisation in the basolateral amygdala

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/Y02-048

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31 July 2017

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