Growth regulation by oncogenes--new insights from model organisms (Q34132813)

31 July 2017

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title

Growth regulation by oncogenes--new insights from model organisms (English)

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31 July 2017

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Prober DA

1

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PubMed ID

11163146

31 July 2017

Edgar BA

series ordinal

2

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31 July 2017

1 February 2001

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Current Opinion in Genetics & Development

31 July 2017

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31 July 2017

11

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31 July 2017

1

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31 July 2017

19-26

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Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Ras signalling is required for inactivation of the tumour suppressor pRb cell-cycle control protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

c-Myc target genes involved in cell growth, apoptosis, and metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Drosophila myc regulates cellular growth during development.

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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Ras1 promotes cellular growth in the Drosophila wing

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

c-Myc enhances protein synthesis and cell size during B lymphocyte development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Control of cell growth by c-Myc in the absence of cell division

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Ventricular expression of a MLC-2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Ras--a versatile cellular switch

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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Mysterious liaisons: the relationship between c-Myc and the cell cycle.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

The Drosophila insulin receptor is required for normal growth

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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Drosophila S6 kinase: a regulator of cell size

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Regulation of cellular growth by the Drosophila target of rapamycin dTOR

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

The conserved phosphoinositide 3-kinase pathway determines heart size in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

1 reference

7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Coordination of growth and cell division in the Drosophila wing.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Cyclin D1 provides a link between development and oncogenesis in the retina and breast.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Expression of cyclin D1 in epithelial tissues of transgenic mice results in epidermal hyperproliferation and severe thymic hyperplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

The Drosophila cyclin D-Cdk4 complex promotes cellular growth

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Sugar control of the plant cell cycle: differential regulation of Arabidopsis D-type cyclin gene expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Cytokinin activation of Arabidopsis cell division through a D-type cyclin.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Cyclin D control of growth rate in plants.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Rescue of Cyclin D1 Deficiency by Knockin Cyclin E

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

A developmentally regulated switch directs regenerative growth of Schwann cells through cyclin D1.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Ras enhances Myc protein stability.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Identification of CDK4 as a target of c-MYC.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1).

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

1 reference

7 January 2021

The hedgehog signalling pathway in tumorigenesis and development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

1 reference

7 January 2021

Identification of c-MYC as a target of the APC pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

TOR signalling and control of cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Amino acids regulate skeletal muscle PHAS-I and p70 S6-kinase phosphorylation independently of insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Coordination of growth with cell division in the yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Coupling of cell division to cell growth by translational control of the G1 cyclin CLN3 in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

The paradox of E2F1: oncogene and tumor suppressor gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Oncogenic potential of cyclin E in T-cell lymphomagenesis in transgenic mice: evidence for cooperation between cyclin E and Ras but not Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Induction of mammary gland hyperplasia in transgenic mice over-expressing human Cdc25B.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Increased susceptibility to carcinogen-induced mammary tumors in MMTV-Cdc25B transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Deregulated cyclin E induces chromosome instability

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Synergistic induction of centrosome hyperamplification by loss of p53 and cyclin E overexpression

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Expression of proto-oncogenes and gene mutation of sarcomeric proteins in patients with hypertrophic cardiomyopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

Induction of ribosomal genes and hepatocyte hypertrophy by adenovirus-mediated expression of c-Myc in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900151-9

7 January 2021

10.1016/S0959-437X(00)00151-9

Identifiers

DOI

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31 July 2017

1 reference

PubMed ID

11163146