The methyltransferase activity of Clr4Suv39h triggers RNAi independently of histone H3K9 methylation. (Q34135321)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20705239%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

The methyltransferase activity of Clr4Suv39h triggers RNAi independently of histone H3K9 methylation (English)

1 reference

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9 February 2020

2

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9 February 2020

author name string

Erica L Gerace

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20705239%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Danesh Moazed

series ordinal

3

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9 February 2020

publication date

1 August 2010

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9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20705239%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

39

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9 February 2020

issue

3

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9 February 2020

page(s)

360-372

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Stc1: a critical link between RNAi and chromatin modification required for heterochromatin integrity.

9 February 2020

cites work

1 reference

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Dicer-independent primal RNAs trigger RNAi and heterochromatin formation

5 July 2018

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Analysis of small RNA in fission yeast; centromeric siRNAs are potentially generated through a structured RNA

5 July 2018

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Synthetic heterochromatin bypasses RNAi and centromeric repeats to establish functional centromeres.

5 July 2018

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An Alpha Motif at Tas3 C Terminus Mediates RITS cis Spreading and Promotes Heterochromatic Gene Silencing

5 July 2018

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Small RNAs in transcriptional gene silencing and genome defence

5 July 2018

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Small silencing RNAs: an expanding universe

5 July 2018

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The emerging field of dynamic lysine methylation of non-histone proteins.

5 July 2018

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Chp1-Tas3 interaction is required to recruit RITS to fission yeast centromeres and for maintenance of centromeric heterochromatin.

5 July 2018

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The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race

5 July 2018

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Methylation of a histone mimic within the histone methyltransferase G9a regulates protein complex assembly

5 July 2018

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Argonaute slicing is required for heterochromatic silencing and spreading

5 July 2018

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RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing

5 July 2018

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The Clr7 and Clr8 directionality factors and the Pcu4 cullin mediate heterochromatin formation in the fission yeast Schizosaccharomyces pombe

5 July 2018

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The Set1 methyltransferase opposes Ipl1 aurora kinase functions in chromosome segregation

5 July 2018

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A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation

5 July 2018

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RNA interference (RNAi)-dependent and RNAi-independent association of the Chp1 chromodomain protein with distinct heterochromatic loci in fission yeast.

5 July 2018

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RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production

5 July 2018

1 reference

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RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing

5 July 2018

1 reference

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A chromodomain protein, Chp1, is required for the establishment of heterochromatin in fission yeast.

5 July 2018

1 reference

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5 July 2018

RNA silencing in plants

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Mechanisms of gene silencing by double-stranded RNA

5 July 2018

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Gene-specific modulation of TAF10 function by SET9-mediated methylation

5 July 2018

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RNAi-mediated targeting of heterochromatin by the RITS complex

5 July 2018

1 reference

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Association of the RENT complex with nontranscribed and coding regions of rDNA and a regional requirement for the replication fork block protein Fob1 in rDNA silencing

5 July 2018

1 reference

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Structure of the SET domain histone lysine methyltransferase Clr4

5 July 2018

1 reference

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Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi

5 July 2018

1 reference

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5 July 2018

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Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly

5 July 2018

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Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

5 July 2018

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Regulation of chromatin structure by site-specific histone H3 methyltransferases

5 July 2018

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Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe

5 July 2018

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Mutations in rik1, clr2, clr3 and clr4 genes asymmetrically derepress the silent mating-type loci in fission yeast

5 July 2018

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Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation.

5 July 2018

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The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon

5 July 2018

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Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations

5 July 2018

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Roles of the Clr4 methyltransferase complex in nucleation, spreading and maintenance of heterochromatin.

5 July 2018

1 reference

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RNA interference in Caenorhabditis elegans.

28 October 2018

1 reference

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A cullin E3 ubiquitin ligase complex associates with Rik1 and the Clr4 histone H3-K9 methyltransferase and is required for RNAi-mediated heterochromatin formation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941148

Tethering RITS to a nascent transcript initiates RNAi- and heterochromatin-dependent gene silencing.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941148

Ubiquitin ligase component Cul4 associates with Clr4 histone methyltransferase to assemble heterochromatin.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941148

Two novel proteins, dos1 and dos2, interact with rik1 to regulate heterochromatic RNA interference and histone modification

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941148

RNA Polymerase II Is Required for RNAi-Dependent Heterochromatin Assembly

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941148

Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941148

Establishment and maintenance of a heterochromatin domain

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941148

Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2941148

Coupling of double-stranded RNA synthesis and siRNA generation in fission yeast RNAi

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20705239

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2010.07.017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20705239%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20705239%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

20705239

1 reference