Chloroquine induces human macrophage killing of Histoplasma capsulatum by limiting the availability of intracellular iron and is therapeutic in a murine model of histoplasmosis (Q34137889)

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English	Chloroquine induces human macrophage killing of Histoplasma capsulatum by limiting the availability of intracellular iron and is therapeutic in a murine model of histoplasmosis	scientific article

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scholarly article

1 reference

Europe PubMed Central

31 July 2017

Chloroquine induces human macrophage killing of Histoplasma capsulatum by limiting the availability of intracellular iron and is therapeutic in a murine model of histoplasmosis (English)

1 reference

Europe PubMed Central

31 July 2017

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inferred from title

Histoplasma capsulatum

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author name string

S L Newman

1

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Europe PubMed Central

31 July 2017

L Gootee

2

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Europe PubMed Central

31 July 2017

G Brunner

3

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Europe PubMed Central

31 July 2017

G S Deepe

4

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Europe PubMed Central

31 July 2017

language of work or name

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publication date

1 April 1994

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Europe PubMed Central

31 July 2017

Journal of Clinical Investigation

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Europe PubMed Central

31 July 2017

93

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Europe PubMed Central

31 July 2017

1422-1429

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Europe PubMed Central

31 July 2017

4

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Europe PubMed Central

31 July 2017

Role of iron in regulation of virulence genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Gamma interferon cooperates with lipopolysaccharide to activate mouse splenic macrophages to an antihistoplasma state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Changes in iron and transferrin levels and body temperature in experimental airborne legionellosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Pharmacologic actions of 4-aminoquinoline compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Iron metabolism of established human hematopoietic cell lines in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Role of iron in Trypanosoma cruzi infection of mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Iron withholding: a defense against infection and neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Role of iron in intracellular growth of Trypanosoma cruzi.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Role of Iron in Microbe-Host Interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

pH and the recycling of transferrin during receptor-mediated endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Lactoferrin and transferrin: a comparative study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

The involvement of lactoferrin in the hyposideremia of acute inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Lysosomal origin of the ferric iron required for cell killing by hydrogen peroxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Chloroquine reduces neuronal and glial iron uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Acid-vesicle function, intracellular pathogens, and the action of chloroquine against Plasmodium falciparum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Role of the adherence-promoting receptors, CR3, LFA-1, and p150,95, in binding of Histoplasma capsulatum by human macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Uptake of ferritin and iron bound to ferritin by rat hepatocytes: modulation by apotransferrin, iron chelators and chloroquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Interferon gamma-activated human monocytes downregulate transferrin receptors and inhibit the intracellular multiplication of Legionella pneumophila by limiting the availability of iron

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Inhibition of tubercle bacilli in cultured human macrophages by chloroquine used alone and in combination with streptomycin, isoniazid, pyrazinamide, and two metabolites of vitamin D3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

The intracellular fate of Histoplasma capsulatum in human macrophages is unaffected by recombinant human interferon-gamma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Phagocytosis of Histoplasma capsulatum yeasts and microconidia by human cultured macrophages and alveolar macrophages. Cellular cytoskeleton requirement for attachment and ingestion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Chloroquine inhibits the intracellular multiplication of Legionella pneumophila by limiting the availability of iron. A potential new mechanism for the therapeutic effect of chloroquine against intracellular pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Protective efficacy of a 62-kilodalton antigen, HIS-62, from the cell wall and cell membrane of Histoplasma capsulatum yeast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Lactoferrin inhibits or promotes Legionella pneumophila intracellular multiplication in nonactivated and interferon gamma-activated human monocytes depending upon its degree of iron saturation. Iron-lactoferrin and nonphysiologic iron chelates rever

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Role of transferrin, transferrin receptors, and iron in macrophage listericidal activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Iron limitation and the gamma interferon-mediated antihistoplasma state of murine macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Inhibition of intracellular growth of Histoplasma capsulatum yeast cells by cytokine-activated human monocytes and macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Digestion of Histoplasma capsulatum yeasts by human macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Colony-stimulating factors activate human macrophages to inhibit intracellular growth of Histoplasma capsulatum yeasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Novel mechanism for translational control in regulation of ferritin synthesis by iron

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Further studies on the intracellular behavior of Torulopsis glabrata

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Secretory responses of human neutrophils: exocytosis of specific (secondary) granules by human neutrophils during adherence in vitro and during exudation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Low molecular weight intracellular iron transport compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Difference between the two iron-binding sites of transferrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

The Effect of pH upon Human Transferrin: Selective Labelling of the Two Iron-binding Sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

5 July 2018

Histoplasma capsulatum modulates the acidification of phagolysosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

28 October 2018

The kinetics and mechanism of iron(3) exchange between chelates and transferrin. IV. The reaction of transferrin with iron(3) nitrilotriacetate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294155

28 October 2018

Factors affecting serum inhibited growth of Candida albicans and Cryptococcus neoformans

1 reference

https://pubmed.ncbi.nlm.nih.gov/8163646

12 December 2020

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inferred from PubMed ID database lookup

REVERSAL OF SERUM FUNGISTASIS BY ADDITION OF IRON

1 reference

https://pubmed.ncbi.nlm.nih.gov/8163646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transferrin-dependent growth inhibition of yeast-phase Histoplasma capsulatum by human serum and lymph

1 reference

https://pubmed.ncbi.nlm.nih.gov/8163646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of functional complement receptors during in vitro maturation of human monocytes into macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/8163646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular pharmacology of deferrioxamine B and derivatives in cultured rat hepatocytes in relation to iron mobilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/8163646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transferrin receptors and transferrin iron uptake by cultured human blood monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8163646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative plating of Histoplasma capsulatum without addition of conditioned medium or siderophores

1 reference

https://pubmed.ncbi.nlm.nih.gov/8163646

12 December 2020

based on heuristic

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The respiratory burst response to Histoplasma capsulatum by human neutrophils. Evidence for intracellular trapping of superoxide anion

1 reference

https://pubmed.ncbi.nlm.nih.gov/8163646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Killing of Histoplasma capsulatum by -interferon-activated human monocyte-derived macrophages: evidence for a superoxide anion-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/8163646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI117119

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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