The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability (Q34139336)

31 July 2017

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title

The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability (English)

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31 July 2017

Harris MH

1

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31 July 2017

Thompson CB

series ordinal

2

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31 July 2017

language of work or name

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1 December 2000

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Cell Death & Differentiation

31 July 2017

published in

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31 July 2017

volume

7

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31 July 2017

issue

12

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31 July 2017

page(s)

1182-1191

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Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism

31 July 2017

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The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling

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Detection of pro-caspase-3 in cytosol and mitochondria of various tissues.

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Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia

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7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

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7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

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The 'ins' and 'outs' of mitochondrial membrane channels

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

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7 January 2021

Regulation of metabolite flux through voltage-gating of VDAC channels.

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7 January 2021

Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Bcl-2-family proteins: the role of the BH3 domain in apoptosis

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7 January 2021

BID: a novel BH3 domain-only death agonist

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7 January 2021

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

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7 January 2021

Bim: a novel member of the Bcl-2 family that promotes apoptosis

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7 January 2021

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

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7 January 2021

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

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7 January 2021

Bcl-xL regulates apoptosis by heterodimerization-dependent and -independent mechanisms

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7 January 2021

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

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7 January 2021

Bcl-x(L) forms an ion channel in synthetic lipid membranes.

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7 January 2021

Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.

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7 January 2021

Channel formation by antiapoptotic protein Bcl-2.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Inhibition of Bax channel-forming activity by Bcl-2

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7 January 2021

Solution structure of BID, an intracellular amplifier of apoptotic signaling

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Ion channel activity of the BH3 only Bcl-2 family member, BID.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

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7 January 2021

Morphological study of the mammalian stress response: characterization of changes in cytoplasmic organelles, cytoskeleton, and nucleoli, and appearance of intranuclear actin filaments in rat fibroblasts after heat-shock treatment

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolism

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

The effects of human recombinant tumor necrosis factor on glioma-derived cell lines: cellular proliferation, cytotoxicity, morphological and radioreceptor studies.

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7 January 2021

The early effects of ischemia upon skeletal muscle mitochondria

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7 January 2021

Ultrastructural bases for metabolically linked mechanical activity in mitochondria. I. Reversible ultrastructural changes with change in metabolic steady state in isolated liver mitochondria

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Regulation of mitochondrial respiration by controlling the permeability of the outer membrane through the mitochondrial channel, VDAC.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Oncogenic alterations of metabolism

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Ultrastructural and biochemical observations on the early changes in apoptotic epithelial cells of the rat prostate induced by castration

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Studies of Energy Transport in Heart Cells. Mitochondrial Isoenzyme of Creatine Phosphokinase: Kinetic Properties and Regulatory Action of Mg2+ Ions

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7 January 2021

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

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7 January 2021

Biochemical and genetic analysis of the mitochondrial response of yeast to BAX and BCL-X(L)

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

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7 January 2021

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

ATP flux is controlled by a voltage-gated channel from the mitochondrial outer membrane

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Role of oxidative phosphorylation in Bax toxicity.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Mitochondria and apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Bcl-x(L) prevents the initial decrease in mitochondrial membrane potential and subsequent reactive oxygen species production during tumor necrosis factor alpha-induced apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Mitochondrial control of nuclear apoptosis.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

The mitochondrial death/life regulator in apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

The mitochondrial permeability transition.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

The molecular structure of mitochondrial contact sites. Their role in regulation of energy metabolism and permeability transition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Reconstitution in planar lipid bilayers of a voltage-dependent anion-selective channel obtained from paramecium mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Voltage gating in the mitochondrial channel, VDAC.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Conversion of Bcl-2 to a Bax-like death effector by caspases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Bax directly induces release of cytochrome c from isolated mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Movement of Bax from the cytosol to mitochondria during apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Regulated targeting of BAX to mitochondria.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Conformation of the Bax C-terminus regulates subcellular location and cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400781

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4400781

1 reference

Dimensions Publication ID

31 July 2017

1016909052

0 references

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