DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines (Q34139601)

31 July 2017

DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines (English)

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31 July 2017

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Erinn B Rankin

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author name string

Eun Ran Suh

1

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31 July 2017

Chong S Ha

2

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31 July 2017

Minoru Toyota

4

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31 July 2017

Peter G Traber

5

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31 July 2017

language of work or name

English

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publication date

17 July 2002

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Journal of Biological Chemistry

31 July 2017

6

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based on heuristic

inferred from page(s)

published in

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31 July 2017

277

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31 July 2017

39

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31 July 2017

35795-35800

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DNA methylation in early development

31 July 2017

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CpG methylation within the 5' regulatory region of the BRCA1 gene is tumor specific and includes a putative CREB binding site

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hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis

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Hypermethylation of the APC (adenomatous polyposis coli) gene promoter region in human colorectal carcinoma.

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An intestine-specific homeobox gene regulates proliferation and differentiation

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Cdx1 promotes differentiation in a rat intestinal epithelial cell line.

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Cdx1 and cdx2 expression during intestinal development

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CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epithelium

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Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells.

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Isolation, characterization, and precise physical localization of human CDX1, a caudal-type homeobox gene

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Novel DNA-binding proteins regulate intestine-specific transcription of the sucrase-isomaltase gene

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COBRA: a sensitive and quantitative DNA methylation assay

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CpG island methylator phenotypes in aging and cancer.

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CpG islands in vertebrate genomes

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

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Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

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DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

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DNA methyltransferase Dnmt1 associates with histone deacetylase activity

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DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

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1 reference

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DNA methylation and genetic instability in colorectal cancer cells

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Identifiers

DOI

10.1074/JBC.M205567200

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31 July 2017

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