Two genetic loci regulate T cell-dependent islet inflammation and drive autoimmune diabetes pathogenesis (Q34141921)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10848492%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

Two genetic loci regulate T cell-dependent islet inflammation and drive autoimmune diabetes pathogenesis (English)

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7 November 2019

2

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7 November 2019

author name string

Fox CJ

series ordinal

1

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7 November 2019

Mortin-Toth SM

series ordinal

3

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7 November 2019

Danska JS

series ordinal

4

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7 November 2019

language of work or name

English

0 references

publication date

9 June 2000

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American Journal of Human Genetics

7 November 2019

published in

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7 November 2019

volume

67

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7 November 2019

issue

1

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7 November 2019

page(s)

67-81

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Macrophage NRAMP1 and its role in resistance to microbial infections

7 November 2019

cites work

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A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus

5 July 2018

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Apoptosis resistance of nonobese diabetic peripheral lymphocytes linked to the Idd5 diabetes susceptibility region

5 July 2018

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Evidence by allelic association-dependent methods for a type 1 diabetes polygene (IDDM6) on chromosome 18q21.

5 July 2018

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Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.

5 July 2018

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IL-4 expression at the onset of islet inflammation predicts nondestructive insulitis in nonobese diabetic mice.

5 July 2018

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5 July 2018

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The role of HLA class II genes in insulin-dependent diabetes mellitus: molecular analysis of 180 Caucasian, multiplex families

5 July 2018

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DPB1*5901a: a novel HLA-DPB1 allele from a Caucasian family with insulin-dependent diabetes mellitus

5 July 2018

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Family study of linkage disequilibrium between TAP2 transporter and HLA class II genes. Absence of TAP2 contribution to association with insulin-dependent diabetes mellitus.

5 July 2018

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Association of HLA-DPB1*0301 with IDDM in Mexican-Americans

5 July 2018

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Multifactorial inheritance in type 1 diabetes

5 July 2018

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5 July 2018

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Polygenic control of autoimmune diabetes in nonobese diabetic mice

5 July 2018

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Localization of the gene for high-density lipoprotein binding protein (HDLBP) to human chromosome 2q37

5 July 2018

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Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

5 July 2018

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Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients

5 July 2018

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Chromosome mapping of the human (RECA) and mouse (Reca) homologs of the yeast RAD51 and Escherichia coli recA genes to human (15q15.1) and mouse (2F1) chromosomes by direct R-banding fluorescence in situ hybridization.

5 July 2018

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A genome-wide search for human type 1 diabetes susceptibility genes

5 July 2018

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Use of recombinant congenic and congenic strains of NOD mice to identify a new insulin-dependent diabetes resistance gene

5 July 2018

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Association of LMP2 and LMP7 genes within the major histocompatibility complex with insulin-dependent diabetes mellitus: population and family studies.

5 July 2018

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Linkage disequilibrium mapping of a type 1 diabetes susceptibility gene (IDDM7) to chromosome 2q31-q33.

5 July 2018

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Genetic control of autoimmune diabetes in the NOD mouse

5 July 2018

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5 July 2018

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Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping

5 July 2018

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5 July 2018

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Breeding of a non-obese, diabetic strain of mice

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

5 July 2018

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Identification of a monoclonal antibody specific for a murine T3 polypeptide

5 July 2018

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The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique

5 July 2018

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A diabetes-susceptible HLA haplotype is best defined by a combination of HLA-DR and -DQ alleles

5 July 2018

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Localization of the acetylcholine receptor gamma subunit gene to human chromosome 2q32----qter.

5 July 2018

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Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat.

5 July 2018

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Mapping of Col3a1 and Col6a3 to proximal murine chromosome 1 identifies conserved linkage of structural protein genes between murine chromosome 1 and human chromosome 2q.

5 July 2018

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Type 1 diabetes in mice is linked to the interleukin-1 receptor and Lsh/lty/Bcg genes on chromosome 1

5 July 2018

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Anti-α/β T cell receptor monoclonal antibody provides an efficient therapy for autoimmune diabetes in nonobese diabetic (NOD) mice

5 July 2018

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NOR/Lt Mice: MHC-Matched Diabetes-Resistant Control Strain for NOD Mice

5 July 2018

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Genetic analysis of autoimmune type 1 diabetes mellitus in mice

5 July 2018

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Autoimmune syndromes in major histocompatibility complex (MHC) congenic strains of nonobese diabetic (NOD) mice. The NOD MHC is dominant for insulitis and cyclophosphamide-induced diabetes.

5 July 2018

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Macrophages, T cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus

5 July 2018

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Multiple TCR V beta usage by infiltrates of young NOD mouse islets of Langerhans. A polymerase chain reaction analysis

5 July 2018

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Antigen presenting cells and the immunogenetics of autoimmune diabetes in NOD mice

5 July 2018

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Properties of Monoclonal Antibodies to Mouse Ig Allotypes, H-2, and Ia Antigens

5 July 2018

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The HLA class II locus DPB1 can influence susceptibility to type 1 diabetes.

5 July 2018

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28 October 2018

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Contribution of T cells to the development of autoimmune diabetes in the NOD mouse model.

28 October 2018

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Tyro 3 receptor tyrosine kinase and its ligand, Gas6, stimulate the function of osteoclasts

28 October 2018

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Subcongenic analysis of the Idd13 locus in NOD/Lt mice: evidence for several susceptibility genes including a possible diabetogenic role for beta 2-microglobulin.

28 October 2018

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Transmission of haplotypes of microsatellite markers rather than single marker alleles in the mapping of a putative type 1 diabetes susceptibility gene (IDDM6)

28 October 2018

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Linkage of type I diabetes to 15q26 (IDDM3) in the Danish population.

28 October 2018

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Receptor tyrosine kinase gene Tyro3 maps to mouse chromosome 2, closely linked to Ltk.

28 October 2018

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Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat.

28 October 2018

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Histological study of pancreatic beta-cell loss in relation to the insulitis process in the non-obese diabetic mouse.

28 October 2018

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The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex

28 October 2018

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Genetic analysis of immune dysfunction in non-obese diabetic (NOD) mice: Mapping of a susceptibility locus close to theBcl-2 gene correlates with increased resistance of NOD T cells to apoptosis induction

28 October 2018

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Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

28 October 2018

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Identification and mapping to chromosome 1 of a susceptibility locus for periinsulitis in non-obese diabetic mice

28 October 2018

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Immunohistochemical characterization of monocytes-macrophages and dendritic cells involved in the initiation of the insulitis and beta-cell destruction in NOD mice

28 October 2018

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12 December 2020

Continued mapping of chromosome 2 genes

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12 December 2020

The HOXD8 locus (2q31) is linked to type I diabetes. Interaction with chromosome 6 and 11 disease susceptibility genes

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Mapping of the gene for high-density lipoprotein binding protein (Hdlbp) to proximal mouse chromosome 1

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12 December 2020

A locus on chromosome 15q26 (IDDM3) produces susceptibility to insulin-dependent diabetes mellitus

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Genomic analysis of the C57BL/Ks mouse strain

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Crosses of NOD mice with the related NON strain. A polygenic model for IDDM

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Who's afraid of epistasis?

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CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice

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Genetic dissection of systemic lupus erythematosus pathogenesis: Sle2 on murine chromosome 4 leads to B cell hyperactivity

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Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1

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12 December 2020

A search for type 1 diabetes susceptibility genes in families from the United Kingdom

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12 December 2020

Mapping multiple linked quantitative trait loci in non-obese diabetic mice using a stepwise regression strategy

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12 December 2020

Genetic analysis of chromosome 2 in type 1 diabetes: analysis of putative loci IDDM7, IDDM12, and IDDM13 and candidate genes NRAMP1 and IA-2 and the interleukin-1 gene cluster. IMDIAB Group

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12 December 2020

Non-major histocompatibility complex-linked diabetes susceptibility loci on chromosomes 4 and 13 in a backcross of the DP-BB/Wor rat to the WF rat

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12 December 2020

Cutting edge: homologous recombination of the MHC class I K region defines new MHC-linked diabetogenic susceptibility gene(s) in nonobese diabetic mice

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12 December 2020

β-Cell Function Relative to Islet Volume and Hormone Content in the Isolated Perfused Mouse Pancreas*

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12 December 2020

Chromosomal localization of muscle nicotinic acetylcholine receptor genes in the mouse

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12 December 2020

Administration of silica particles or anti-Lyt2 antibody prevents beta-cell destruction in NOD mice given cyclophosphamide

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12 December 2020

The natural history of lymphocyte subsets infiltrating the pancreas of NOD mice

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12 December 2020

The gene for retinal S-antigen (48-kDa protein) maps to the centromeric portion of mouse chromosome 1 near Idh-1

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12 December 2020

Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat

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12 December 2020

Markers on distal chromosome 2q linked to insulin-dependent diabetes mellitus

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12 December 2020

Production of congenic mouse strains carrying NOD-derived diabetogenic genetic intervals: An approach for the genetic dissection of complex traits

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12 December 2020

Programmed cell death in the pathogenesis of murine IDDM: resistance to apoptosis induced in lymphocytes by cyclophosphamide

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12 December 2020

Encyclopedia of the mouse genome V. Mouse chromosome 1

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12 December 2020

Encyclopedia of the mouse genome V. Mouse chromosome 2

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12 December 2020

Backcross analysis of genes linked to autoantibody production in New Zealand White mice

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12 December 2020

Independent genetic regulation of T-cell and antigen-presenting cell participation in autoimmune islet inflammation

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12 December 2020

Localization of two insulin-dependent diabetes (Idd) genes to the Idd10 region on mouse Chromosome 3

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12 December 2020

Flow cytometric enumeration of mononuclear cell populations infiltrating the islets of Langerhans in prediabetic NOD mice: development of a model of autoimmune insulitis for type I diabetes

1 reference

12 December 2020

Reconstitution of (BALB/c x B6)F1 normal mice with stem cells and thymus from nonobese diabetic mice results in autoimmune insulitis of the normal hosts' pancreases

1 reference

12 December 2020

Identifiers

DOI

10.1086/302995

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10848492%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10848492%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

PubMed publication ID

10848492

1 reference