Potentiation of temozolomide cytotoxicity by inhibition of DNA polymerase beta is accentuated by BRCA2 mutation (Q34146866)

31 July 2017

title

Potentiation of temozolomide cytotoxicity by inhibition of DNA polymerase beta is accentuated by BRCA2 mutation (English)

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31 July 2017

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5

Joann B Sweasy

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31 July 2017

Gregory C Stachelek

1

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31 July 2017

Shibani Dalal

2

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31 July 2017

Katherine A Donigan

3

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31 July 2017

Denise Campisi Hegan

4

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31 July 2017

Peter M Glazer

6

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31 July 2017

language of work or name

English

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publication date

22 December 2009

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31 July 2017

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31 July 2017

volume

70

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31 July 2017

issue

1

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31 July 2017

page(s)

409-417

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describes a project that uses

31 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2943728/fullTextXML

inferred from PubMed Central ID database lookup

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Potentiation of temozolomide cytotoxicity by poly(ADP)ribose polymerase inhibitor ABT-888 requires a conversion of single-stranded DNA damages to double-stranded DNA breaks.

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5 July 2018

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5 July 2018

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5 July 2018

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Temozolomide, a novel alkylating agent with activity in the central nervous system, may improve the treatment of advanced metastatic melanoma

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens

5 July 2018

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28 October 2018

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O6-methylguanine-DNA methyltransferase-deficient phenotype in human gliomas: frequency and time to tumor progression after alkylating agent-based chemotherapy

28 October 2018

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Lithocholic acid, a putative tumor promoter, inhibits mammalian DNA polymerase beta.

28 October 2018

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Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps

28 October 2018

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Involvement of the mismatch repair system in temozolomide-induced apoptosis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943728

Amplification of the BRCA2 Pathway Gene EMSY in Sporadic Breast Cancer Is Related to Negative Outcome

28 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943728

THE GENETICS OF BREAST CANCER SUSCEPTIBILITY

28 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943728

Structure of lithocholic acid binding to the N-terminal 8-kDa domain of DNA polymerase beta

28 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20028873

12 December 2020

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Differential Contributions ofBRCA1andBRCA2to Early-Onset Breast Cancer

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20028873

12 December 2020

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RAD51, BRCA2 and DNA repair: a partial resolution

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20028873

12 December 2020

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Identifiers

DOI

10.1158/0008-5472.CAN-09-1353

1 reference

31 July 2017

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31 July 2017

1 reference