Radiation therapy causes loss of dermal lymphatic vessels and interferes with lymphatic function by TGF-beta1-mediated tissue fibrosis (Q34149752)

31 July 2017

Radiation therapy causes loss of dermal lymphatic vessels and interferes with lymphatic function by TGF-beta1-mediated tissue fibrosis (English)

1 reference

Adriana Haimovitz-Friedman

31 July 2017

0 references

5

object named as

Adriana Haimovitz-Friedman

1 reference

31 July 2017

Tomer Avraham

1

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31 July 2017

Alan Yan

2

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31 July 2017

Jamie C Zampell

3

1 reference

31 July 2017

Sanjay V Daluvoy

4

1 reference

31 July 2017

Andrew P Cordeiro

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31 July 2017

Babak J Mehrara

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31 July 2017

2 June 2010

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American Journal of Physiology - Cell Physiology

31 July 2017

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31 July 2017

299

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31 July 2017

3

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31 July 2017

C589-605

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Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-kappaB and Prox1.

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Senescence impairs successful reprogramming to pluripotent stem cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Biomarkers for epithelial-mesenchymal transitions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is associated with the risk of radiation pneumonitis in patients with non-small-cell lung cancer treated with definitive radiotherapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

The risk of developing arm lymphedema among breast cancer survivors: a meta-analysis of treatment factors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Prevalence of lymphedema in women with breast cancer 5 years after sentinel lymph node biopsy or axillary dissection: patient perceptions and precautionary behaviors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

TGFbeta-induced protein mediates lymphatic endothelial cell adhesion to the extracellular matrix under low oxygen conditions.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Inhibition of endogenous TGF-beta signaling enhances lymphangiogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Cellular and molecular mechanisms of fibrosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Methods to detect biomarkers of cellular senescence: the senescence-associated beta-galactosidase assay

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Absence of Smad3 confers radioprotection through modulation of ERK-MAPK in primary dermal fibroblasts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Radiogenic lymphangiogenesis in the skin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

FGF-2 suppresses cellular senescence of human mesenchymal stem cells by down-regulation of TGF-beta2.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Lymphedema following axillary lymph node dissection for breast cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Sequelae following axillary lymph node dissection for breast cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

The incidence of symptomatic lower-extremity lymphedema following treatment of uterine corpus malignancies: a 12-year experience at Memorial Sloan-Kettering Cancer Center

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Methoxyamine potentiates iododeoxyuridine-induced radiosensitization by altering cell cycle kinetics and enhancing senescence

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

p21Waf1/Cip1 plays a critical role in modulating senescence through changes of DNA methylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Induction of p21CIP/WAF-1 and G2 arrest by ionizing irradiation impedes caspase-3-mediated apoptosis in human carcinoma cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Hematopoietic stem cell senescence and long-term bone marrow injury

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Enhanced G2-M arrest by nuclear factor-{kappa}B-dependent p21waf1/cip1 induction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Combinations of radioprotectants spare radiation-induced damage to the physis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Smad3 is required for dedifferentiation of retinal pigment epithelium following retinal detachment in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

TGF-beta signaling and the fibrotic response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Successful shape-based virtual screening: the discovery of a potent inhibitor of the type I TGFbeta receptor kinase (TbetaRI).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Interference with transforming growth factor-beta/ Smad3 signaling results in accelerated healing of wounds in previously irradiated skin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

TGFBI gene transcript is transforming growth factor-beta1-responsive and cell density-dependent in a human corneal epithelial cell line

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Radioprotectants: current status and new directions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Loss of heterozygosity at the mannose 6-phosphate insulin-like growth factor 2 receptor (M6P/IGF2R) locus predisposes patients to radiation-induced lung injury

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Radiation-induced senescence-like growth arrest requires TP53 function but not telomere shortening

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Induced p21waf expression in H1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Quality of life of breast cancer patients with lymphedema.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Enhanced expression of transforming growth factor-beta type I and type II receptors in wound granulation tissue and hypertrophic scar

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Telomeres, senescence and cellular radiation response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Radiation-induced apoptosis in microvascular endothelial cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Morphological and immunochemical differences between keloid and hypertrophic scar

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Heparanase activity in cultured endothelial cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Lymphedema and quality of life in breast cancer survivors: the Iowa Women's Health Study.

28 July 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Fibrosis is a key inhibitor of lymphatic regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Single nucleotide polymorphisms, apoptosis, and the development of severe late adverse effects after radiotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

TGF-beta1 is a negative regulator of lymphatic regeneration during wound repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Fractionated doses of ionizing radiation confer protection to mesenchymal stem cell pluripotency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Amifostine: an update on its clinical status as a cytoprotectant in patients with cancer receiving chemotherapy or radiotherapy and its potential therapeutic application in myelodysplastic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Protection by WR-2721 and WR-151327 against late effects of gamma rays and neutrons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Lymphedema after breast cancer: incidence, risk factors, and effect on upper body function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Lymphedema secondary to postmastectomy radiation: incidence and risk factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Vascular endothelial growth factor-A mediates ultraviolet B-induced impairment of lymphatic vessel function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Overcoming of radioresistance in human gliomas by p21WAF1/CIP1 antisense oligonucleotide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Predictors of lymphedema in patients with breast cancer undergoing axillary lymph node dissection in Hong Kong

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

TGF-beta1 and radiation fibrosis: a master switch and a specific therapeutic target?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Variation in lymphatic function may predispose to development of breast cancer-related lymphoedema.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Ionizing radiation of mesenchymal stem cells results in diminution of the precursor pool and limits potential for multilineage differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Volume measurement in lymphoedema treatment: examination of formulae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Breast cancer-related lymphedema--what are the significant predictors and how they affect the severity of lymphedema?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Risk, severity and predictors of physical and psychological morbidity after axillary lymph node dissection for breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00535.2009

Immunolocalization of basic fibroblast growth factor and fibroblast growth factor receptor-1 and receptor-2 in rat cranial sutures

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944320

Changes in the Lymph Structure of the Upper Limb after Axillary Dissection: Radiographic and Anatomical Study in a Human Cadaver

28 October 2018

1 reference

12 December 2020

Activation of the VEGFR-3 pathway by VEGF-C attenuates UVB-induced edema formation and skin inflammation by promoting lymphangiogenesis

1 reference

12 December 2020

Lymphatic drainage in the muscle and subcutis of the arm after breast cancer treatment

1 reference

12 December 2020

Lymphedema in a cohort of breast carcinoma survivors 20 years after diagnosis

1 reference

12 December 2020

Lymphedema in women treated for breast cancer

1 reference

12 December 2020

1 reference

12 December 2020

Temporal modulation of TGF-beta 1 and beta-actin gene expression in pig skin and muscular fibrosis after ionizing radiation

1 reference

12 December 2020

Intestinal and peri-tumoral lymphatic endothelial cells are resistant to radiation-induced apoptosis

1 reference

12 December 2020

Short-term exposure to transforming growth factor beta induces long-term fibrotic responses

1 reference

12 December 2020

10.1152/AJPCELL.00535.2009

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DOI

1 reference

31 July 2017

1 reference

31 July 2017

1 reference