Phenomics: the next challenge (Q34150453)

31 July 2017

Phenomics: the next challenge (English)

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31 July 2017

David Houle

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author name string

Diddahally R Govindaraju

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2

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PubMed ID

21085204

31 July 2017

Stig Omholt

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3

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31 July 2017

1 December 2010

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31 July 2017

Nature Reviews Genetics

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31 July 2017

11

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12

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31 July 2017

855-866

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https://scigraph.springernature.com/pub.10.1038/nrg2897

31 July 2017

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cites work

Genetics of complex disease: approaches, problems, and solutions

1 reference

The Correlation between Relatives on the Supposition of Mendelian Inheritance

21 January 2018

1 reference

The dimensionality of genetic variation for wing shape in Drosophila melanogaster.

21 January 2018

1 reference

The NCBI dbGaP database of genotypes and phenotypes

21 January 2018

1 reference

Proposal to sequence the human genome stirs debate

21 January 2018

1 reference

Toward metabolic phenomics: analysis of genomic data using flux balances

31 March 2020

1 reference

Characters as the Units of Evolutionary Change

31 March 2020

1 reference

Phenomics: the systematic study of phenotypes on a genome-wide scale

31 March 2020

1 reference

The human phenome project

31 March 2020

1 reference

Strategies for the physiome project

31 March 2020

1 reference

Hereditary genius: An inquiry into its laws and consequences

31 March 2020

1 reference

Mathematical Contributions to the Theory of Evolution. XI. On the Influence of Natural Selection on the Variability and Correlation of Organs

31 March 2020

1 reference

Genetical genomics: the added value from segregation.

31 March 2020

1 reference

Studying complex biological systems using multifactorial perturbation.

31 March 2020

1 reference

Reverse engineering the genotype-phenotype map with natural genetic variation

31 March 2020

1 reference

Pleiotropic scaling of gene effects and the 'cost of complexity'.

31 March 2020

1 reference

Toward a molecular understanding of pleiotropy

31 March 2020

1 reference

Genomic patterns of pleiotropy and the evolution of complexity

31 March 2020

1 reference

Foraging strategies of Drosophila melanogaster: a chromosomal analysis.

31 March 2020

1 reference

The Drosophila foraging gene mediates adult plasticity and gene-environment interactions in behaviour, metabolites, and gene expression in response to food deprivation

31 March 2020

1 reference

Hundreds of variants clustered in genomic loci and biological pathways affect human height

31 March 2020

1 reference

Finding the missing heritability of complex diseases

31 March 2020

1 reference

Estimation of effect size distribution from genome-wide association studies and implications for future discoveries

31 March 2020

1 reference

Biological, clinical and population relevance of 95 loci for blood lipids

31 March 2020

1 reference

Personal genomes: The case of the missing heritability

31 March 2020

1 reference

Common SNPs explain a large proportion of the heritability for human height

31 March 2020

1 reference

Common genetic variation and human traits

31 March 2020

1 reference

Understanding and using quantitative genetic variation

31 March 2020

1 reference

Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies

31 March 2020

1 reference

Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk

31 March 2020

1 reference

Genotype score in addition to common risk factors for prediction of type 2 diabetes

31 March 2020

1 reference

Performance of common genetic variants in breast-cancer risk models

31 March 2020

1 reference

Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study

31 March 2020

1 reference

Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene–gene interaction

31 March 2020

1 reference

Dissecting complex disease: the quest for the Philosopher's Stone?

31 March 2020

1 reference

Measuring sexual selection on females in sex-role-reversed Mormon crickets (Anabrus simplex, Orthoptera: Tettigoniidae).

31 March 2020

1 reference

THE MEASUREMENT OF SELECTION ON CORRELATED CHARACTERS

31 March 2020

1 reference

Colloquium papers: Numbering the hairs on our heads: the shared challenge and promise of phenomics

31 March 2020

1 reference

Common disorders are quantitative traits

31 March 2020

1 reference

The endophenotype concept in psychiatry: etymology and strategic intentions

31 March 2020

1 reference

Variation, selection and evolution of function-valued traits

31 March 2020

1 reference

Analysis of the relationship between type traits and functional survival in Canadian Holsteins using a Weibull proportional hazards model.

31 March 2020

1 reference

Knowledge-based data analysis comes of age.

31 March 2020

1 reference

An integrative genomics approach to the reconstruction of gene networks in segregating populations.

31 March 2020

1 reference

Identifying SNPs predictive of phenotype using random forests

31 March 2020

1 reference

Statistical Modeling: The Two Cultures (with comments and a rejoinder by the author)

31 March 2020

1 reference

When parameters in dynamic models become phenotypes: a case study on flesh pigmentation in the chinook salmon (Oncorhynchus tshawytscha).

31 March 2020

1 reference

Integration from proteins to organs: the Physiome Project

31 March 2020

1 reference

Nonlinear regulation enhances the phenotypic expression of trans-acting genetic polymorphisms

31 March 2020

1 reference

Threshold-dominated regulation hides genetic variation in gene expression networks

31 March 2020

1 reference

The selective values of alleles in a molecular network model are context dependent.

31 March 2020

1 reference

Modeling QTL for complex traits: detection and context for plant breeding.

31 March 2020

1 reference

A computational model of teeth and the developmental origins of morphological variation.

31 March 2020

1 reference

Statistical epistasis is a generic feature of gene regulatory networks

31 March 2020

1 reference

Allele interaction--single locus genetics meets regulatory biology

31 March 2020

1 reference

A vision and strategy for the virtual physiological human in 2010 and beyond.

31 March 2020

1 reference

Computational Mechanics of the Heart

31 March 2020

1 reference

A decade of genome-wide gene expression profiling in acute myeloid leukemia: flashback and prospects

31 March 2020

1 reference

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

31 March 2020

1 reference

Quantitative genomics: analyzing intraspecific variation using global gene expression polymorphisms or eQTLs.

31 March 2020

1 reference

A statistical problem for inference to regulatory structure from associations of gene expression measurements with microarrays

31 March 2020

1 reference

Spatial expression profiles in the Xenopus laevis oocytes measured with qPCR tomography.

31 March 2020

1 reference

Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast

31 March 2020

1 reference

Decoding signalling networks by mass spectrometry-based proteomics

31 March 2020

1 reference

Widely targeted metabolomics based on large-scale MS/MS data for elucidating metabolite accumulation patterns in plants

31 March 2020

1 reference

Metabolomics: ready for the prime time?

31 March 2020

1 reference

Human metabolic phenotype diversity and its association with diet and blood pressure.

31 March 2020

1 reference

Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events

31 March 2020

1 reference

Erratum: Visualization of image data from cells to organisms

31 March 2020

1 reference

Novel throughput phenotyping platforms in plant genetic studies

31 March 2020

1 reference

Temperature responses of roots: impact on growth, root system architecture and implications for phenotyping

31 March 2020

1 reference

Miniature neurologgers for flying pigeons: multichannel EEG and action and field potentials in combination with GPS recording

31 March 2020

1 reference

A new chamber for studying the behavior of Drosophila

31 March 2020

1 reference

Natural and sexual selection in a wild insect population.

31 March 2020

1 reference

Internet vs. paper and pencil administration of questionnaires commonly used in panic/agoraphobia research

31 March 2020

1 reference

High-dimensional and large-scale phenotyping of yeast mutants.

31 March 2020

1 reference

Automated on-chip rapid microscopy, phenotyping and sorting of C. elegans

31 March 2020

1 reference

Genetics of the Framingham Heart Study population

31 March 2020

1 reference

Multiple biomarkers for the prediction of first major cardiovascular events and death

31 March 2020

1 reference

Age, Gene/Environment Susceptibility-Reykjavik Study: multidisciplinary applied phenomics

31 March 2020

1 reference

Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts

31 March 2020

1 reference

Colloquium papers: Natural selection in a contemporary human population

31 March 2020

1 reference

The Danish National Birth Cohort - its background, structure and aim

31 March 2020

1 reference

Microfluidics-enabled phenotyping, imaging, and screening of multicellular organisms

31 March 2020

1 reference

Drivers of biodiagnostic development

31 March 2020

1 reference

Probing genetic overlap among complex human phenotypes.

31 March 2020

1 reference

Mouse MRI: concepts and applications in physiology

31 March 2020

1 reference

Influence of substrate supply on cardiac efficiency, as measured by pressure-volume analysis in ex vivo mouse hearts

31 March 2020

1 reference

A unique micromechanocalorimeter for simultaneous measurement of heat rate and force production of cardiac trabeculae carneae.

31 March 2020

1 reference

Extended confocal microscopy of myocardial laminae and collagen network

31 March 2020

1 reference

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease

31 March 2020

1 reference

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease

31 March 2020

1 reference

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging

31 March 2020

1 reference

Stochastic modelling for quantitative description of heterogeneous biological systems.

31 March 2020

1 reference

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

31 March 2020

1 reference

Lipids, lipid modifying agents and cardiovascular risk: a review of the evidence

31 March 2020

1 reference

Major lipids, apolipoproteins, and risk of vascular disease

31 March 2020

1 reference

An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing

31 March 2020

1 reference

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

31 March 2020

1 reference

Measuring the accuracy of diagnostic systems

31 March 2020

1 reference

Digital quantification of human eye color highlights genetic association of three new loci

31 March 2020

1 reference

Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines.

31 March 2020

1 reference

Systems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster

31 March 2020

1 reference

THE NUMBER OF ALLELES THAT CAN BE MAINTAINED IN A FINITE POPULATION

31 March 2020

1 reference

12 December 2020

A comprehensive evaluation of family history and breast cancer risk. The Utah Population Database

1 reference

12 December 2020

Vast, 15-year effort to decipher genes stirs opposition

1 reference

12 December 2020

Gene regulatory networks generating the phenomena of additivity, dominance and epistasis.

1 reference

12 December 2020

The Danish National Birth Cohort--its background, structure and aim.

1 reference

12 December 2020

The Enterprise Data Trust at Mayo Clinic: a semantically integrated warehouse of biomedical data

1 reference

12 December 2020

Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project

1 reference

12 December 2020

Common disorders are quantitative traits

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRG2897

1 reference

PubMed ID

21085204

Dimensions Publication ID

31 July 2017

0 references

1 reference

PubMed ID

21085204