Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival. (Q34151699)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20823247%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival (English)

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13 February 2020

4

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13 February 2020

Nikhil S. Joshi

5

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13 February 2020

author name string

Timothy W Hand

1

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13 February 2020

Weiguo Cui

2

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13 February 2020

Yong Woo Jung

3

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13 February 2020

Anmol Chandele

6

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13 February 2020

Ying Liu

7

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13 February 2020

Susan M Kaech

8

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language of work or name

English

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publication date

7 September 2010

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13 February 2020

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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13 February 2020

volume

107

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issue

38

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13 February 2020

page(s)

16601-16606

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Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties

13 February 2020

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5 July 2018

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5 July 2018

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Intrinsic and extrinsic control of effector T cell survival and memory T cell development

5 July 2018

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5 July 2018

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Formation of IL-7Ralphahigh and IL-7Ralphalow CD8 T cells during infection is regulated by the opposing functions of GABPalpha and Gfi-1.

5 July 2018

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Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

5 July 2018

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The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells

5 July 2018

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Effector CD8 T cell development: a balancing act between memory cell potential and terminal differentiation

5 July 2018

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IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival

5 July 2018

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Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor

5 July 2018

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Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells.

5 July 2018

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Loss of T cell receptor-induced Bmi-1 in the KLRG1(+) senescent CD8(+) T lymphocyte

5 July 2018

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Expression of IL-7 receptor alpha is necessary but not sufficient for the formation of memory CD8 T cells during viral infection

5 July 2018

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Activation phenotype, rather than central- or effector-memory phenotype, predicts the recall efficacy of memory CD8+ T cells

5 July 2018

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AKT/PKB signaling: navigating downstream

5 July 2018

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Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis

5 July 2018

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5 July 2018

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Impaired CD8 T cell memory and CD4 T cell primary responses in IL-7R alpha mutant mice

5 July 2018

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5 July 2018

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Augmented IL-7 signaling during viral infection drives greater expansion of effector T cells but does not enhance memory

5 July 2018

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5 July 2018

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IL-15 regulates CD8+ T cell contraction during primary infection.

5 July 2018

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5 July 2018

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Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets

5 July 2018

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A permissive role for phosphatidylinositol 3-kinase in the Stat5-mediated expression of cyclin D2 by the interleukin-2 receptor

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation

5 July 2018

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Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.

5 July 2018

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Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination

21 January 2018

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IL-12 signaling drives CD8+ T cell IFN-gamma production and differentiation of KLRG1+ effector subpopulations during Toxoplasma gondii Infection.

21 January 2018

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Constitutive expression of IL-7 receptor alpha does not support increased expansion or prevent contraction of antigen-specific CD4 or CD8 T cells following Listeria monocytogenes infection.

21 January 2018

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KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells.

21 January 2018

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Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo

21 January 2018

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A role for Stat5 in CD8+ T cell homeostasis.

21 January 2018

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Distinct effects of STAT5 activation on CD4+ and CD8+ T cell homeostasis: development of CD4+CD25+ regulatory T cells versus CD8+ memory T cells.

21 January 2018

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Serine protease inhibitor 2A is a protective factor for memory T cell development

21 January 2018

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Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI3-kinase in myeloid leukemias

21 January 2018

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Dual roles of IL-15 in maintaining IL-7RalphalowCCR7- memory CD8+ T cells in humans via recovering the phosphatidylinositol 3-kinase/AKT pathway

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20823247

12 December 2020

inferred from PubMed ID database lookup

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20823247

12 December 2020

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Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20823247

12 December 2020

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Identifiers

DOI

10.1073/PNAS.1003457107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20823247%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

0 references

1 reference

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13 February 2020

PubMed publication ID

20823247

1 reference