Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome (Q34154044)

31 July 2017

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome (English)

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31 July 2017

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Paul G Ekert

6

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Francesco Cecconi

Francesco Cecconi

8

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Philippe Bouillet

Philippe Bouillet

14

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John Silke

John Silke

4

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David L Vaux

David L Vaux

13

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Andreas Strasser

Andreas Strasser

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Donald Metcalf

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Donald Metcalf

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31 July 2017

Vanessa S Marsden

1

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31 July 2017

Liam O'Connor

2

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31 July 2017

Lorraine A O'Reilly

3

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31 July 2017

David C S Huang

7

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31 July 2017

Keisuke Kuida

9

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31 July 2017

Kevin J Tomaselli

10

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31 July 2017

Sophie Roy

11

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31 July 2017

Don W Nicholson

12

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31 July 2017

Jerry M Adams

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31 July 2017

language of work or name

English

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publication date

25 September 2002

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31 July 2017

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31 July 2017

419

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634-637

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31 July 2017

6907

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https://scigraph.springernature.com/pub.10.1038/nature01101

31 July 2017

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cites work

The biochemistry of apoptosis

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The Bcl2 family: regulators of the cellular life-or-death switch

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Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

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7 January 2021

Differential requirement for caspase 9 in apoptotic pathways in vivo.

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7 January 2021

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

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7 January 2021

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

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7 January 2021

Mitochondria and apoptosis

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https://api.crossref.org/works/10.1038%2FNATURE01101

7 January 2021

BCL-2 family members and the mitochondria in apoptosis

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https://api.crossref.org/works/10.1038%2FNATURE01101

7 January 2021

https://api.crossref.org/works/10.1038%2FNATURE01101

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7 January 2021

Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L).

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https://api.crossref.org/works/10.1038%2FNATURE01101

7 January 2021

Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2

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7 January 2021

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

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7 January 2021

Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival

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7 January 2021

Adult Apaf-1-deficient mice exhibit male infertility

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7 January 2021

Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2.

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https://api.crossref.org/works/10.1038%2FNATURE01101

7 January 2021

Two distinct pathways leading to nuclear apoptosis

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https://api.crossref.org/works/10.1038%2FNATURE01101

7 January 2021

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

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https://api.crossref.org/works/10.1038%2FNATURE01101

7 January 2021

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

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7 January 2021

Irreversible caspase inhibitors: tools for studying apoptosis

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7 January 2021

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

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7 January 2021

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

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https://api.crossref.org/works/10.1038%2FNATURE01101

7 January 2021

The apoptotic protease-activating factor 1-mediated pathway of apoptosis is dispensable for negative selection of thymocytes.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01101

7 January 2021

Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

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https://api.crossref.org/works/10.1038%2FNATURE01101

7 January 2021

The role of cytochrome c in caspase activation in Drosophila melanogaster cells

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7 January 2021

The role of ARK in stress-induced apoptosis in Drosophila cells

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7 January 2021

Defects in regulation of apoptosis in caspase-2-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01101

7 January 2021

Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01101

7 January 2021

Apoptosomes: engines for caspase activation

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7 January 2021

Identifiers

DOI

10.1038/NATURE01101

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Dimensions Publication ID

31 July 2017

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