Trypacidin, a spore-borne toxin from Aspergillus fumigatus, is cytotoxic to lung cells (Q34154554)

31 July 2017

Trypacidin, a spore-borne toxin from Aspergillus fumigatus, is cytotoxic to lung cells (English)

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31 July 2017

Aspergillus fumigatus

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cytotoxicity

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fumiquinazoline C

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ChEBI release 2020-05-28

Thierry Gauthier

1

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Nicolas Loiseau

Nicolas Loiseau

Joice Sifuentes Dos Santos

8

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Joice Sifuentes Dos Santos

3

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Olivier Puel

Olivier Puel

10

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Isabelle P Oswald

Isabelle P Oswald

9

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Souria Tadrist

5

Souria Tadrist

1 reference

31 July 2017

6

Cécile Canlet

1 reference

31 July 2017

7

Marie Pierre Artigot

1 reference

31 July 2017

Xiaodi Wang

2

1 reference

PubMed ID

22319557

31 July 2017

Athanasios Fysikopoulos

4

1 reference

PubMed ID

22319557

31 July 2017

language of work or name

English

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publication date

3 February 2012

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31 July 2017

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31 July 2017

7

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31 July 2017

2

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31 July 2017

e29906

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Creative Commons Attribution 4.0 International

31 July 2017

start time

3 February 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Complexity generation in fungal peptidyl alkaloid biosynthesis: oxidation of fumiquinazoline A to the heptacyclic hemiaminal fumiquinazoline C by the flavoenzyme Af12070 from Aspergillus fumigatus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Enzymatic processing of fumiquinazoline F: a tandem oxidative-acylation strategy for the generation of multicyclic scaffolds in fungal indole alkaloid biosynthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

SMURF: Genomic mapping of fungal secondary metabolite clusters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Fungal secondary metabolites - strategies to activate silent gene clusters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Fungal spores: a critical review of the toxicological and epidemiological evidence as a basis for occupational exposure limit setting

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Efficient activation of p53 pathway in A549 cells exposed to L2, a novel compound targeting p53-MDM2 interaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Effects of conidia of various Aspergillus species on apoptosis of human pneumocytes and bronchial epithelial cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Metabolites from the endophytic mitosporic Dothideomycete sp. LRUB20.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Transcriptional profiling identifies a role for BrlA in the response to nitrogen depletion and for StuA in the regulation of secondary metabolite clusters in Aspergillus fumigatus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Occupational rhinitis in damp and moldy workplaces

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

What do we know about the role of gliotoxin in the pathobiology of Aspergillus fumigatus?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Microbiological contamination with moulds in work environment in libraries and archive storage facilities.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Production of mycotoxins by Aspergillus lentulus and other medically important and closely related species in section Fumigati.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Verruculogen associated with Aspergillus fumigatus hyphae and conidia modifies the electrophysiological properties of human nasal epithelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

The fumitremorgin gene cluster of Aspergillus fumigatus: identification of a gene encoding brevianamide F synthetase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Polyphasic taxonomy of Aspergillus fumigatus and related species

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Abundant respirable ergot alkaloids from the common airborne fungus Aspergillus fumigatus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Detection of gliotoxin in experimental and human aspergillosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Gliotoxin-induced cytotoxicity proceeds via apoptosis and is mediated by caspases and reactive oxygen species in LLC-PK1 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Aspergillus fumigatus and aspergillosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Mitochondria and apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Diffusible component from the spore surface of the fungus Aspergillus fumigatus which inhibits the macrophage oxidative burst is distinct from gliotoxin and other hyphal toxins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

DNA content histogram and cell-cycle analysis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272003

Determination of volatile metabolites originating from mould growth on wall paper and synthetic media

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029906

Genetic diversity of Aspergillus fumigatus in indoor hospital environments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029906

Acute pulmonary aspergillosis in immunocompetent subjects after exposure to bark chippings

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029906

Fatal acute granulomatous pulmonary aspergillosis in a healthy subject after inhalation of vegetal dust.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029906

Species-specific profiles of mycotoxins produced in cultures and associated with conidia of airborne fungi derived from biowaste

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029906

Mycotoxins of Aspergillus fumigatus in pure culture and in native bioaerosols from compost facilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029906

Association of ergot alkaloids with conidiation in Aspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029906

Gliotoxin-mediated apoptosis of activated human hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029906

Lutein protects HT-29 cells against Deoxynivalenol-induced oxidative stress and apoptosis: prevention of NF-kappaB nuclear localization and down regulation of NF-kappaB and Cyclo-Oxygenase-2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029906

Inflammation-associated gene transcription and expression in mouse lungs induced by low molecular weight compounds from fungi from the built environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029906

Comparison of inflammatory and cytotoxic lung responses in mice after intratracheal exposure to spores of two different Stachybotrys chartarum strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029906

Metabolomics ofAspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029906

Evolutionary Relationships in Aspergillus Section Fumigati Inferred from Partial b-Tubulin and Hydrophobin DNA Sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029906

Culture filtrates of Aspergillus fumigatus induce different modes of cell death in human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029906

Hidden biosynthetic treasures brought to light

21 January 2018

1 reference

12 December 2020

The production of trypacidin and monomethylsulochrin by Aspergillus fumigatus

1 reference

12 December 2020

Detection of elevated reactive oxygen species level in cultured rat hepatocytes treated with aflatoxin B1

1 reference

12 December 2020

ANTIPROTOZOAL ANTIBIOTICS. II. ISOLATION AND CHARACTERIZATION OF TRYPACIDIN, A NEW ANTIBIOTIC, ACTIVE AGAINST TRYPANOSOMA CRUZI AND TOXOPLASMA GONDII

1 reference

12 December 2020

THE STRUCTURE OF TRYPACIDIN

1 reference

12 December 2020

Gardening can seriously damage your health

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0029906

Identifiers

DOI

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference

PubMed ID

22319557