LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion of breast cancer cells (Q34155989)

31 July 2017

LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion of breast cancer cells (English)

1 reference

31 July 2017

1 reference

L Taliaferro-Smith

1

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31 July 2017

A Nagalingam

2

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31 July 2017

D Zhong

3

1 reference

31 July 2017

W Zhou

4

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31 July 2017

N K Saxena

5

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31 July 2017

D Sharma

6

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31 July 2017

language of work or name

English

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publication date

1 June 2009

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31 July 2017

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31 July 2017

28

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31 July 2017

2621-2633

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31 July 2017

29

1 reference

https://scigraph.springernature.com/pub.10.1038/onc.2009.129

31 July 2017

0 references

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Cell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27Kip1 or p21Cip1.

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LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins

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5 July 2018

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5 July 2018

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Growth-inhibitory effect of adiponectin via adiponectin receptor 1 on human breast cancer cells through inhibition of S-phase entry without inducing apoptosis

5 July 2018

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Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression

5 July 2018

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5 July 2018

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Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells

5 July 2018

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leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3

5 July 2018

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Antiproliferative effect of adiponectin on MCF7 breast cancer cells: a potential hormonal link between obesity and cancer

5 July 2018

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Total and high-molecular-weight adiponectin in breast cancer: in vitro and in vivo studies

5 July 2018

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Adiponectin modulates the glycogen synthase kinase-3beta/beta-catenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice.

5 July 2018

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Demonstration of adiponectin receptors 1 and 2 mRNA expression in human breast cancer cells

5 July 2018

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Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells

5 July 2018

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Adiponectin: a link between obesity and cancer

5 July 2018

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LKB1-dependent signaling pathways

5 July 2018

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Ribosomal protein S6 phosphorylation: from protein synthesis to cell size.

5 July 2018

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Adiponectin mediates antiproliferative and apoptotic responses in human MCF7 breast cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

AMPK and cell proliferation--AMPK as a therapeutic target for atherosclerosis and cancer

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

Adiponectin and cancer: a systematic review

5 July 2018

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Chutes and Ladders: the search for protein kinases that act on AMPK.

5 July 2018

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Adipose tissue, adipokines, and inflammation

5 July 2018

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New roles for the LKB1-->AMPK pathway.

5 July 2018

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The expanding TOR signaling network

5 July 2018

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Adiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization-dependent manner.

5 July 2018

1 reference

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AMPK, the metabolic syndrome and cancer

5 July 2018

1 reference

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Analysis of the LKB1-STRAD-MO25 complex

5 July 2018

1 reference

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The AMP-activated protein kinase pathway--new players upstream and downstream.

5 July 2018

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Obesity, adipocytokines, and insulin resistance in breast cancer

5 July 2018

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T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin

5 July 2018

1 reference

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Adiponectin: A novel adipokine linking adipocytes and vascular function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

Adiponectin and breast cancer risk

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

Adiponectin and Metabolic Syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

Growth arrest by the LKB1 tumor suppressor: induction of p21(WAF1/CIP1).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

Relation of body mass index to tumor markers and survival among young women with invasive ductal breast carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

AdipoQ is a novel adipose-specific gene dysregulated in obesity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

A novel serum protein similar to C1q, produced exclusively in adipocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945727

AMPK inhibits fatty acid-induced increases in NF-kappaB transactivation in cultured human umbilical vein endothelial cells.

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.129

Serum adiponectin and leptin levels in Taiwanese breast cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.129

Impaired activation of AMP-kinase and fatty acid oxidation by globular adiponectin in cultured human skeletal muscle of obese type 2 diabetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.129

Body mass index, height, and postmenopausal breast cancer mortality in a prospective cohort of US women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.129

Adiponectin and protection against type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.129

LKB1 protein expression in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.129

Adiponectin and leptin expression in primary ductal breast cancer and in adjacent healthy epithelial and myoepithelial tissue

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.129

Adiponectin stimulates human osteoblasts proliferation and differentiation via the MAPK signaling pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.129

Low plasma adiponectin levels predict progression of coronary artery calcification

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.129

Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.129

Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.129

Association of serum adiponectin levels with breast cancer risk

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19483724

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2009.129

1 reference

Dimensions Publication ID

31 July 2017

0 references

1 reference

31 July 2017

1 reference