Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation (Q34156078)

31 July 2017

Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation (English)

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31 July 2017

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systemic inflammation

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Daniel Halperin

5

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Luis Ulloa

object named as

Luis Ulloa

1

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Kevin J. Tracey

object named as

Kevin J Tracey

9

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author name string

Mahendar Ochani

2

1 reference

31 July 2017

Huan Yang

3

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31 July 2017

Mahira Tanovic

4

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31 July 2017

Runkuan Yang

6

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31 July 2017

Christopher J Czura

7

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31 July 2017

Mitchell P Fink

8

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31 July 2017

language of work or name

English

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publication date

3 September 2002

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31 July 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

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published in

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31 July 2017

99

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31 July 2017

19

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31 July 2017

12351-12356

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Reactive oxygen species as mediators of organ dysfunction caused by sepsis, acute respiratory distress syndrome, or hemorrhagic shock: potential benefits of resuscitation with Ringer's ethyl pyruvate solution

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

HMGB1 as a late mediator of lethal systemic inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

Dual roles for HMGB1: DNA binding and cytokine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

Inflammation, coagulopathy, and the pathogenesis of multiple organ dysfunction syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

Hypoxia-inducible factor 1-mediated inhibition of peroxisome proliferator-activated receptor alpha expression during hypoxia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

Proinflammatory cytokines (tumor necrosis factor and interleukin 1) stimulate release of high mobility group protein-1 by pituicytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

HMG-1 as a late mediator of endotoxin lethality in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

Two forms of NF-kappa B1 (p105/p50) in murine macrophages: differential regulation by lipopolysaccharide, interleukin-2, and interferon-gamma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

Mitogen-activated protein (MAP) kinase regulates production of tumor necrosis factor-alpha and release of arachidonic acid in mast cells. Indications of communication between p38 and p42 MAP kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

Tyrosine phosphorylation of mitogen-activated protein kinases is necessary for activation of murine macrophages by natural and synthetic bacterial products

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

Shock and tissue injury induced by recombinant human cachectin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

Regulation of NF-?B activity in murine macrophages: Effect of bacterial lipopolysaccharide and phorbol ester

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

Ringer's ethyl pyruvate solution ameliorates ischemia/reperfusion-induced intestinal mucosal injury in rats

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.192222999

Resuscitation from hemorrhagic shock with Ringer's ethyl pyruvate solution improves survival and ameliorates intestinal mucosal hyperpermeability in rats

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.192222999

Coagulation and inflammation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.192222999

Ethyl pyruvate modulates inflammatory gene expression in mice subjected to hemorrhagic shock

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129448

Cytokine appearance in human endotoxemia and primate bacteremia

28 October 2018

1 reference

12 December 2020

Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome. Results from a randomized, double-blind, placebo-controlled trial. Phase III rhIL-1ra Sepsis Syndrome Study Group

1 reference

12 December 2020

Establishment of lipopolysaccharide-dependent nuclear factor kappa B activation in a cell-free system

1 reference

12 December 2020

Melatonin Administration Following Hemorrhagic Shock Decreases Mortality from Subsequent Septic Challenge

1 reference

12 December 2020

Double-blind randomised controlled trial of monoclonal antibody to human tumour necrosis factor in treatment of septic shock. NORASEPT II Study Group

1 reference

12 December 2020

HMG-1 as a mediator of acute lung inflammation

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.192222999

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31 July 2017

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1 reference

31 July 2017

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