Enoyl-CoA hydratase. reaction, mechanism, and inhibition (Q34162857)

31 July 2017

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title

Enoyl-CoA hydratase. reaction, mechanism, and inhibition (English)

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31 July 2017

Gautam Agnihotri

1

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31 July 2017

Hung-wen Liu

series ordinal

2

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31 July 2017

language of work or name

English

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publication date

1 January 2003

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Bioorganic & Medicinal Chemistry

31 July 2017

published in

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31 July 2017

volume

11

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31 July 2017

issue

1

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31 July 2017

page(s)

9-20

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beta-oxidation of fatty acids in mitochondria, peroxisomes, and bacteria: a century of continued progress

31 July 2017

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Bovine liver crotonase (enoyl coenzyme A hydratase). EC 4.2.1.17 L-3-hydroxyacyl-CoA hydrolyase

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Enoyl-coenzyme A hydratase-catalyzed exchange of the alpha-protons of coenzyme A thiol esters: a model for an enolized intermediate in the enzyme-catalyzed elimination?

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Properties of mitochondria and peroxisomal enoyl-CoA hydratases from rat liver

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Studies on the inactivation of bovine liver enoyl-CoA hydratase by (methylenecyclopropyl)formyl-CoA: elucidation of the inactivation mechanism and identification of cysteine-114 as the entrapped nucleophile

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Enoyl-CoA Hydratase and Isomerase form a Superfamily with a Common Active-Site Glutamate Residue

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The crotonase superfamily: divergently related enzymes that catalyze different reactions involving acyl coenzyme a thioesters

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The crystal structure of enoyl-CoA hydratase complexed with octanoyl-CoA reveals the structural adaptations required for binding of a long chain fatty acid-CoA molecule

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Structural mechanism of enoyl-CoA hydratase: three atoms from a single water are added in either an E1cb stepwise or concerted fashion

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Importance of historical contingency in the stereochemistry of hydratase-dehydratase enzymes

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Electronic Rearrangement Induced by Substrate Analog Binding to the Enoyl-CoA Hydratase Active Site: Evidence for Substrate Activation

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Localized electron polarization in a substrate analog binding to the active site of enoyl-CoA hydratase: Raman spectroscopic and conformational analyses of rotamers of hexadienoyl thiolesters

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Site-directed mutagenesis of putative active-site amino acid residues of 3,2-trans-enoyl-CoA isomerase, conserved within the low-homology isomerase/hydratase enzyme family

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Role of glutamate 144 and glutamate 164 in the catalytic mechanism of enoyl-CoA hydratase

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Involvement of glycine 141 in substrate activation by enoyl-CoA hydratase

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Novel inactivation of enoyl-CoA hydratase via beta-elimination of 5, 6-dichloro-7,7,7-trifluoro-4-thia-5-heptenoyl-CoA

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A revised mechanism for the inactivation of bovine liver enoyl-CoA hydratase by (methylenecyclopropyl)formyl-CoA based on unexpected results with the C114A mutant

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Identifiers

DOI

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31 July 2017

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