The role and regulation of urokinase-type plasminogen activator receptor gene expression in cancer invasion and metastasis (Q34165118)

31 July 2017

1 reference

title

The role and regulation of urokinase-type plasminogen activator receptor gene expression in cancer invasion and metastasis (English)

1 reference

31 July 2017

1 reference

1 reference

Wang Y

1

1 reference

31 July 2017

1 March 2001

1 reference

Medicinal Research Reviews

31 July 2017

1 reference

31 July 2017

21

1 reference

31 July 2017

2

1 reference

31 July 2017

146-170

1 reference

Purification of zymogen to plasminogen activator from human glioblastoma cells by affinity chromatography with monoclonal antibody.

31 July 2017

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Generation and characterization of urokinase receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Increase in urokinase plasminogen activator mRNA synthesis in human carcinoma cells is a primary effect of the potent tumor promoter, phorbol myristate acetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Protein structure and membrane anchorage of the cellular receptor for urokinase-type plasminogen activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Domain 1 of the urokinase receptor (uPAR) is required for uPAR-mediated cell binding to vitronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Structure-function relationships in the receptor for urokinase-type plasminogen activator. Comparison to other members of the Ly-6 family and snake venom alpha-neurotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Removal of domain D2 or D3 of the human urokinase receptor does not affect ligand affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Urokinase-type plasminogen activator/type-2 plasminogen-activator inhibitor complexes are not internalized upon binding to the urokinase-type-plasminogen-activator receptor in THP-1 cells. Interaction of urokinase-type plasminogen activator/type-2 p

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Two alternatively spliced mouse urokinase receptor mRNAs with different histological localization in the gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Molecular cloning of cDNA for the bovine urokinase-type plasminogen activator receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Bovine urokinase-type plasminogen activator and its receptor: cloning and induction by retinoic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Isolation and characterization of multiple isoforms of the rat urokinase receptor in osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Structure of the human urokinase receptor gene and its similarity to CD59 and the Ly-6 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

A ligand-free, soluble urokinase receptor is present in the ascitic fluid from patients with ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

An alternatively spliced variant of mRNA for the human receptor for urokinase plasminogen activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

uPA, uPAR, PAI-1: key intersection of proteolytic, adhesive and chemotactic highways?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Upregulation of urokinase receptor expression on migrating endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Biosynthesis and apical localization of the urokinase receptor in polarized MDCK epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Decreased urokinase receptor expression by overexpression of the plasminogen activator in a colon cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

A region between -141 and -61 bp containing a proximal AP-1 is essential for constitutive expression of urokinase-type plasminogen activator receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Requirement of an upstream AP-1 motif for the constitutive and phorbol ester-inducible expression of the urokinase-type plasminogen activator receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Elevated urokinase-type plasminogen activator receptor expression in a colon cancer cell line is due to a constitutively activated extracellular signal-regulated kinase-1-dependent signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Stimulation of urokinase-type plasminogen activator receptor expression by PMA requires JNK1-dependent and -independent signaling modules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Targeted disruption of the K-ras oncogene in an invasive colon cancer cell line down-regulates urokinase receptor expression and plasminogen-dependent proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Transactivation of the urokinase-type plasminogen activator receptor gene through a novel promoter motif bound with an activator protein-2alpha-related factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Regulation of urokinase receptor transcription by Ras- and Rho-family GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Studies and perspectives of protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Protein lipidation in cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Induction of cell migration by pro-urokinase binding to its receptor: possible mechanism for signal transduction in human epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Urokinase-type plasminogen activator stimulates the Ras/Extracellular signal-regulated kinase (ERK) signaling pathway and MCF-7 cell migration by a mechanism that requires focal adhesion kinase, Src, and Shc. Rapid dissociation of GRB2/Sps-Shc compl

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

The urokinase-type plasminogen activator receptor, a GPI-linked protein, is localized in caveolae

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Identification of a urokinase receptor-integrin interaction site. Promiscuous regulator of integrin function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Molecular role(s) for integrins in human melanoma invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

The urokinase-type plasminogen activator system in cancer metastasis: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Prevention of metastasis by inhibition of the urokinase receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Co-expression of urokinase, urokinase receptor and PAI-1 is necessary for optimum invasiveness of cultured lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Overexpression of urokinase receptor in breast cancer cells results in increased tumor invasion, growth and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Prognostic value of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitors PAI-1 and PAI-2 in breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Urokinase receptor and colorectal cancer survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Urokinase-type plasminogen activator and its receptor in colorectal cancer: independent prognostic factors of metastasis and cancer-specific survival and potential therapeutic targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Blockage of the urokinase receptor on the cell surface: construction and characterization of a hybrid protein consisting of the N-terminal fragment of human urokinase and human albumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Saturation of tumour cell surface receptors for urokinase-type plasminogen activator by amino-terminal fragment and subsequent effect on reconstituted basement membranes invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

The role of the urokinase receptor in extracellular matrix degradation by HT29 human colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Recombinant soluble urokinase receptor as a scavenger for urokinase-type plasminogen activator (uPA). Inhibition of proliferation and invasion of human ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

Physiological consequences of loss of plasminogen activator gene function in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1098-1128%28200103%2921%3A2%3C146%3A%3AAID-MED1004%3E3.0.CO%3B2-B

10.1002/1098-1128(200103)21:2<146::AID-MED1004>3.0.CO;2-B

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

11223863