A proposed structure for transmembrane segment 7 of G protein-coupled receptors incorporating an asn-Pro/Asp-Pro motif (Q34168551)

31 July 2017

A proposed structure for transmembrane segment 7 of G protein-coupled receptors incorporating an asn-Pro/Asp-Pro motif (English)

1 reference

G protein-coupled receptor

31 July 2017

0 references

transmembrane protein

0 references

0 references

0 references

K Konvicka

1

1 reference

31 July 2017

F Guarnieri

series ordinal

2

1 reference

31 July 2017

J A Ballesteros

series ordinal

3

1 reference

31 July 2017

H Weinstein

series ordinal

4

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 August 1998

1 reference

31 July 2017

11

1 reference

based on heuristic

inferred from page(s)

published in

Biophysical Journal

1 reference

31 July 2017

75

1 reference

31 July 2017

2

1 reference

31 July 2017

601-611

1 reference

Static and dynamic roles of extracellular loops in G-protein-coupled receptors: a mechanism for sequential binding of thyrotropin-releasing hormone to its receptor.

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Agonists induce conformational changes in transmembrane domains III and VI of the beta2 adrenoceptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

The transmembrane 7-alpha-bundle of rhodopsin: distance geometry calculations with hydrogen bonding constraints

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Functional and structural complexity of signal transduction via G-protein-coupled receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Connectivity and orientation of the seven helical bundle in the tachykinin NK-1 receptor probed by zinc site engineering

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Residues in the seventh membrane-spanning segment of the dopamine D2 receptor accessible in the binding-site crevice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Probing the structure and function of the tachykinin neurokinin-2 receptor through biosynthetic incorporation of fluorescent amino acids at specific sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Arrangement of transmembrane domains in adrenergic receptors. Similarity to bacteriorhodopsin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Projection structure of frog rhodopsin in two crystal forms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Modeling alpha-helical transmembrane domains: the calculation and use of substitution tables for lipid-facing residues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

The probable arrangement of the helices in G protein-coupled receptors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Satisfying hydrogen bonding potential in proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Structure of G-protein-linked receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Structure and function of receptors coupled to G proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

A cysteine residue in the third membrane-spanning segment of the human D2 dopamine receptor is exposed in the binding-site crevice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Locating ligand-binding sites in 7TM receptors by protein engineering.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Functional role of proline and tryptophan residues highly conserved among G protein-coupled receptors studied by mutational analysis of the m3 muscarinic receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Mutational analysis of the relative orientation of transmembrane helices I and VII in G protein-coupled receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Mapping light-dependent structural changes in the cytoplasmic loop connecting helices C and D in rhodopsin: a site-directed spin labeling study.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

A General Method for Mapping Tertiary Contacts between Amino Acid Residues in Membrane-Embedded Proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Amino acid preferences for specific locations at the ends of alpha helices

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Receptor-effector coupling by G proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Model systems for the study of seven-transmembrane-segment receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

The role of Pro/Hyp-kinks in determining the transmembrane helix length and gating mechanism of a [Leu]zervamicin channel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Modeling of G-protein-coupled receptors: application to dopamine, adrenaline, serotonin, acetylcholine, and mammalian opsin receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

The ligand-binding domain of rhodopsin and other G protein-linked receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

The Protein Data Bank: a computer-based archival file for macromolecular structures

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Comparative modeling and molecular dynamics studies of the delta, kappa and mu opioid receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Residues in the fifth membrane-spanning segment of the dopamine D2 receptor exposed in the binding-site crevice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Ligand-induced domain motion in the activation mechanism of a G-protein-coupled receptor.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Arrangement of rhodopsin transmembrane α-helices

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299736

Functional Microdomains in G-protein-coupled Receptors

28 October 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

Three-dimensional structure of the highly conserved seventh transmembrane domain of G-protein-coupled receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

The G-protein nanomachine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

Fluorescent labeling of purified beta 2 adrenergic receptor. Evidence for ligand-specific conformational changes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

A refined model of the thyrotropin-releasing hormone (TRH) receptor binding pocket. Novel mixed mode Monte Carlo/stochastic dynamics simulations of the complex between TRH and TRH receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

Three-dimensional structure for the β2 adrenergic receptor protein based on computer modeling studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

Equation of State Calculations by Fast Computing Machines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

Interactions between conserved residues in transmembrane helices 1, 2, and 7 of the thyrotropin-releasing hormone receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

Formation of the meta II photointermediate is accompanied by conformational changes in the cytoplasmic surface of rhodopsin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

Geometry of proline-containing alpha-helices in proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

Semianalytical treatment of solvation for molecular mechanics and dynamics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

Molecular Architecture of G Protein-Coupled Receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

Structure and function in rhodopsin. Single cysteine substitution mutants in the cytoplasmic interhelical E-F loop region show position-specific effects in transducin activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

Signal transduction by a 5-HT2 receptor: a mechanistic hypothesis from molecular dynamics simulations of the three-dimensional model of the receptor complexed to ligands

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

Polarity conserved positions in transmembrane domains of G-protein coupled receptors and bacteriorhodopsin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2898%2977551-4

The catecholamine binding site of the beta-adrenergic receptor is formed by juxtaposed membrane-spanning domains

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9675163

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A reciprocal mutation supports helix 2 and helix 7 proximity in the gonadotropin-releasing hormone receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9675163

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/S0006-3495(98)77551-4

1 reference

31 July 2017

1 reference

31 July 2017

1 reference