Therapeutic hypothermia for acute ischemic stroke: ready to start large randomized trials? (Q34171143)

31 July 2017

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title

Therapeutic hypothermia for acute ischemic stroke: ready to start large randomized trials? (English)

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31 July 2017

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1

H Bart van der Worp

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31 July 2017

Malcolm R Macleod

2

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author name string

Rainer Kollmar

series ordinal

3

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PubMed ID

20354545

31 July 2017

European Stroke Research Network for Hypothermia (EuroHYP)

series ordinal

4

1 reference

31 July 2017

31 March 2010

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Journal of Cerebral Blood Flow & Metabolism

31 July 2017

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31 July 2017

30

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31 July 2017

1079-1093

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31 July 2017

6

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Publication bias in reports of animal stroke studies leads to major overstatement of efficacy

31 July 2017

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Defeating normal thermoregulatory defenses: induction of therapeutic hypothermia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Thermoregulatory defense mechanisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials

5 July 2018

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The Paracetamol (Acetaminophen) In Stroke (PAIS) trial: a multicentre, randomised, placebo-controlled, phase III trial

5 July 2018

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Therapeutic hypothermia and controlled normothermia in the intensive care unit: practical considerations, side effects, and cooling methods

5 July 2018

1 reference

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Penumbral selection of patients for trials of acute stroke therapy

5 July 2018

1 reference

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Hypothermia in focal ischemia: implications of experiments and experience

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Use of prolonged hypothermia to treat ischemic and hemorrhagic stroke.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Cooling therapy for acute stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Methodology of the Interventional Management of Stroke III Trial

5 July 2018

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Metabolic downregulation: a key to successful neuroprotection?

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

5 July 2018

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Long-term hypothermia reduces infarct volume in aged rats after focal ischemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Hypothermia treatment for traumatic brain injury: a systematic review and meta-analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Acute ischaemic stroke and infection: recent and emerging concepts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Cerebral autoregulation: the role of CO2 in metabolic homeostasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Cooling for newborns with hypoxic ischaemic encephalopathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

How can we improve the pre-clinical development of drugs for stroke?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Clinical practice. Acute ischemic stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

General versus specific actions of mild-moderate hypothermia in attenuating cerebral ischemic damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Arrhenius temperature dependence of in vitro tissue plasminogen activator thrombolysis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Hypothermia in animal models of acute ischaemic stroke: a systematic review and meta-analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Meperidine and skin surface warming additively reduce the shivering threshold: a volunteer study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Systematic review and meta-analysis of the efficacy of tirilazad in experimental stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Measurement of brain temperature with magnetic resonance spectroscopy in acute ischemic stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Diagnosis and treatment of ventilator-associated pneumonia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

1,026 experimental treatments in acute stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Microbubble administration accelerates clot lysis during continuous 2-MHz ultrasound monitoring in stroke patients treated with intravenous tissue plasminogen activator.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Clinical and economic consequences of ventilator-associated pneumonia: a systematic review.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Methodological quality of animal studies on neuroprotection in focal cerebral ischaemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Central nervous system injury-induced immune deficiency syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Effects of low temperature on shear-induced platelet aggregation and activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Delayed onset of prolonged hypothermia improves outcome after intracerebral hemorrhage in rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Preventive antibacterial treatment improves the general medical and neurological outcome in a mouse model of stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Admission body temperature predicts long-term mortality after acute stroke: the Copenhagen Stroke Study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Endovascular cooling for moderate hypothermia in patients with acute stroke: first results of a novel approach

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Hypothermia induces T-cell production of immunosuppressive cytokines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Feasibility and safety of moderate hypothermia after massive hemispheric infarction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Cooling for acute ischemic brain damage (cool aid): an open pilot study of induced hypothermia in acute ischemic stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Core cooling by central venous infusion of ice-cold (4 degrees C and 20 degrees C) fluid: isolation of core and peripheral thermal compartments

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Intracerebral steal phenomenon associated with global hyperemia in moyamoya disease during revascularization surgery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Recommendations for standards regarding preclinical neuroprotective and restorative drug development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Relative contribution of skin and core temperatures to vasoconstriction and shivering thresholds during isoflurane anesthesia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Pathobiology of ischaemic stroke: an integrated view

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Moderate hypothermia in the treatment of patients with severe middle cerebral artery infarction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Tramadol reduces the sweating, vasoconstriction, and shivering thresholds.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Natural history of the spontaneous reperfusion of human cerebral infarcts as assessed by 99mTc HMPAO SPECT.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Dexmedetomidine does not alter the sweating threshold, but comparably and linearly decreases the vasoconstriction and shivering thresholds.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Mild postischemic hypothermia limits cerebral injury following transient focal ischemia in rat neocortex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Rate and gender dependence of the sweating, vasoconstriction, and shivering thresholds in humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Platelet kinetics during deep hypothermia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Cerebral autoregulation and flow/metabolism coupling during cardiopulmonary bypass: the influence of PaCO2.

5 July 2018

1 reference

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Reduction by delayed hypothermia of cerebral infarction following middle cerebral artery occlusion in the rat: a time-course study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Metabolic benefits of surface counter warming during therapeutic temperature modulation.

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Increasing mean skin temperature linearly reduces the core-temperature thresholds for vasoconstriction and shivering in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Cooling for Acute Ischemic Brain Damage (COOL AID): a feasibility trial of endovascular cooling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Induction of mild systemic hypothermia with endovascular cooling during primary percutaneous coronary intervention for acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Neither arm nor face warming reduces the shivering threshold in unanesthetized humans.

21 January 2018

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https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Hemicraniectomy and moderate hypothermia in patients with severe ischemic stroke

21 January 2018

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https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

A trial of therapeutic hypothermia via endovascular approach in awake patients with acute ischemic stroke: methodology.

21 January 2018

1 reference

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Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Hypothermia Therapy after Traumatic Brain Injury in Children

21 January 2018

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https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Feasibility of endovascular cooling as an adjunct to primary percutaneous coronary intervention (results of the LOWTEMP pilot study).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

The early immunological response to acute ischemic stroke: differential gene expression in subpopulations of mononuclear cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Effects of hypothermia on thrombin-induced brain edema formation

21 January 2018

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https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Theoretical evaluations of therapeutic systemic and local cerebral hypothermia.

21 January 2018

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https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

The low normothermia concept--maintaining a core body temperature between 36 and 37 degrees C in acute stroke unit patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Different degrees of hypothermia after experimental stroke: short- and long-term outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Early effects of acid-base management during hypothermia on cerebral infarct volume, edema, and cerebral blood flow in acute focal cerebral ischemia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Alpha-stat versus pH-stat guided ventilation in patients with large ischemic stroke treated by hypothermia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Ice-cold saline for the induction of mild hypothermia in patients with acute ischemic stroke: a pilot study

21 January 2018

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[Incidence, etiology and long-term prognosis of stroke]

21 January 2018

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https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Role of nitric oxide in the regulation of cerebral blood flow in humans: chemoregulation versus mechanoregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Intravascular Cooling in the Treatment of Stroke (ICTuS): early clinical experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Effect of deprivation on time to hospital in acute stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Delayed induction and long-term effects of mild hypothermia in a focal model of transient cerebral ischemia: neurological outcome and infarct size

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Mild hypothermia: therapeutic window after experimental cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Heat flow and distribution during induction of general anesthesia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

The influence of body temperature on infarct volume and thrombolytic therapy in a rat embolic stroke model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

In search of clinical neuroprotection after brain ischemia: the case for mild hypothermia (35 degrees C) and magnesium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Buspirone and meperidine synergistically reduce the shivering threshold

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Therapeutic time window of post-ischemic mild hypothermia and the gene expression associated with the neuroprotection in rat focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Monitoring intracranial pressure in patients with malignant middle cerebral artery infarction: is it useful?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Induction of hypothermia in patients with various types of neurologic injury with use of large volumes of ice-cold intravenous fluid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Noninvasive selective brain cooling by head and neck cooling is protective in severe traumatic brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Hypothermic protection in rat focal ischemia models: strain differences and relevance to "reperfusion injury".

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Mild and moderate hypothermia increases platelet aggregation induced by various agonists: a whole blood in vitro study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Effect of mild hypothermia on the thrombolytic efficacy of 120 kHz ultrasound enhanced thrombolysis in an in-vitro human clot model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Greater Incidence of Both Fatal and Nonfatal Strokes in Disadvantaged Areas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Head and neck cooling after cardiac arrest results in lower jugular bulb than esophageal temperature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Rapid and selective cerebral hypothermia achieved using a cooling helmet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Magnesium sulfate increases the rate of hypothermia via surface cooling and improves comfort

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

The effectiveness of rapidly infused intravenous fluids for inducing moderate hypothermia in neurosurgical patients.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Relative contribution of core and cutaneous temperatures to thermal comfort and autonomic responses in humans.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949207

Ultrasound-Enhanced Systemic Thrombolysis for Acute Ischemic Stroke

28 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Can We Improve the Statistical Analysis of Stroke Trials?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

A Very Early Rehabilitation Trial (AVERT)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Very Early Mobilisation and Complications in the First 3 Months after Stroke: Further Results from Phase II of A Very Early Rehabilitation Trial (AVERT)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.44

Shiver suppression using focal hand warming in unanesthetized normal subjects

21 January 2018

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12 December 2020

Changes in coagulation and fibrinolysis occurring in dogs during hypothermia

1 reference

12 December 2020

Disseminated Intravascular Coagulation During Rewarming Following Hypothermia

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12 December 2020

Facial warming increases the threshold for shivering

1 reference

12 December 2020

Perioperative effects of alpha-stat versus ph-stat strategies for deep hypothermic cardiopulmonary bypass in infants

1 reference

12 December 2020

Combination therapy of moderate hypothermia and thrombolysis in experimental thromboembolic stroke--an MRI study

1 reference

12 December 2020

Enhanced platelet aggregation and activation under conditions of hypothermia

1 reference

12 December 2020

Hypothermia-induced reversible platelet dysfunction

1 reference

12 December 2020

Clonidine comparably decreases the thermoregulatory thresholds for vasoconstriction and shivering in humans

1 reference

12 December 2020

A pilot study: the Noninvasive Surface Cooling Thermoregulatory System for Mild Hypothermia Induction in Acute Myocardial Infarction (the NICAMI Study)

1 reference

12 December 2020

Adrenergic, respiratory, and cardiovascular effects of core cooling in humans

1 reference

12 December 2020

Thresholds in cerebral ischemia - the ischemic penumbra

1 reference

12 December 2020

Intranasal selective brain cooling in pigs

1 reference

12 December 2020

Thrombolysis with tissue plasminogen activator (tPA) is temperature dependent

1 reference

12 December 2020

Inhibition of shivering in man by thermal stimulation of the facial area

1 reference

12 December 2020

The effects of selective brain hypothermia on intracerebral hemorrhage in rats

1 reference

12 December 2020

Direct influence of mild hypothermia on cytokine expression and release in cultures of human peripheral blood mononuclear cells

1 reference

12 December 2020

Thermoregulatory vasococonstriction and shivering impede therapeutic hypothermia in acute ischemic stroke patients

1 reference

12 December 2020

Feasibility and safety of inducing modest hypothermia in awake patients with acute stroke through surface cooling: A case-control study: the Copenhagen Stroke Study

1 reference

12 December 2020

Coagulation defects resulting from ambient temperature-induced hypothermia

1 reference

12 December 2020

Metabolic cost of shivering

1 reference

12 December 2020

Spontaneous reperfusion of cerebral infarcts in patients with acute stroke. Incidence, time course, and clinical outcome in the Copenhagen Stroke Study

1 reference

12 December 2020

Combination of intraischemic and postischemic hypothermia provides potent and persistent neuroprotection against temporary focal ischemia in rats

1 reference

12 December 2020

Comparison of 12, 24 and 48 h of systemic hypothermia on outcome after permanent focal ischemia in rat

1 reference

12 December 2020

Induced hypothermia using large volume, ice-cold intravenous fluid in comatose survivors of out-of-hospital cardiac arrest: a preliminary report

1 reference

12 December 2020

Moderate superficial hypothermia prolongs bleeding time in humans

1 reference

12 December 2020

Hyperthermic fibrinolysis with rt-PA: in vitro results

1 reference

12 December 2020

Mild resuscitative hypothermia to improve neurological outcome after cardiac arrest. A clinical feasibility trial. Hypothermia After Cardiac Arrest (HACA) Study Group

1 reference

12 December 2020

Effect of hypothermia and delayed thrombolysis in a rat embolic stroke model

1 reference

12 December 2020

Identifiers

DOI

10.1038/JCBFM.2010.44

1 reference

31 July 2017

1 reference

31 July 2017

1 reference

PubMed ID

20354545