The metalloregulatory zinc site in Streptococcus pneumoniae AdcR, a zinc-activated MarR family repressor (Q34172538)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804771%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

The metalloregulatory zinc site in Streptococcus pneumoniae AdcR, a zinc-activated MarR family repressor (English)

1 reference

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13 February 2020

main subject

Streptococcus pneumoniae

1 reference

2

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13 February 2020

Robert A Scott

7

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13 February 2020

David P. Giedroc

9

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13 February 2020

author name string

Hermes Reyes-Caballero

1

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13 February 2020

Faith E Jacobsen

3

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13 February 2020

Krystyna M Kazmierczak

4

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13 February 2020

Darin Cowart

5

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13 February 2020

Uma Mahendra Kumar Koppolu

6

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13 February 2020

Malcolm E Winkler

8

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13 February 2020

language of work or name

English

0 references

publication date

8 September 2010

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Journal of Molecular Biology

13 February 2020

published in

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13 February 2020

volume

403

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13 February 2020

issue

2

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13 February 2020

page(s)

197-216

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A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome

13 February 2020

cites work

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Unnatural amino acid substitution as a probe of the allosteric coupling pathway in a mycobacterial Cu(I) sensor

5 July 2018

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Metal binding affinities of Arabidopsis zinc and copper transporters: selectivities match the relative, but not the absolute, affinities of their amino-terminal domains

5 July 2018

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Solution structure of a paradigm ArsR family zinc sensor in the DNA-bound state

5 July 2018

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Coordination chemistry of bacterial metal transport and sensing

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Coordination dynamics of zinc in proteins

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Metalloproteins and metal sensing

5 July 2018

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Contributions of Zur-controlled ribosomal proteins to growth under zinc starvation conditions

5 July 2018

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The Laminin-Binding Protein Lbp from Streptococcus pyogenes Is a Zinc Receptor

5 July 2018

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The metal homeostasis protein, Lsp, of Streptococcus pyogenes is necessary for acquisition of zinc and virulence

5 July 2018

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Influences of capsule on cell shape and chain formation of wild-type and pcsB mutants of serotype 2 Streptococcus pneumoniae.

5 July 2018

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Molecular insights into the metal selectivity of the copper(I)-sensing repressor CsoR from Bacillus subtilis

5 July 2018

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A summary of the measured pK values of the ionizable groups in folded proteins

5 July 2018

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A Cu(I)-sensing ArsR family metal sensor protein with a relaxed metal selectivity profile.

5 July 2018

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The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism.

5 July 2018

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Functional definition and global regulation of Zur, a zinc uptake regulator in a Streptococcus suis serotype 2 strain causing streptococcal toxic shock syndrome

5 July 2018

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AdcAII, a new pneumococcal Zn-binding protein homologous with ABC transporters: biochemical and structural analysis

5 July 2018

1 reference

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Ni(II) and Co(II) sensing by Escherichia coli RcnR.

5 July 2018

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Microarray analysis of Streptococcus pneumoniae gene expression changes to human lung epithelial cells

5 July 2018

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Analysis of the protective capacity of three Streptococcus suis proteins induced under divalent-cation-limited conditions

5 July 2018

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Pneumococcal virulence gene expression and host cytokine profiles during pathogenesis of invasive disease

5 July 2018

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Structure of the zinc transporter YiiP

5 July 2018

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The novel transcriptional regulator SczA mediates protection against Zn2+ stress by activation of the Zn2+-resistance gene czcD in Streptococcus pneumoniae

5 July 2018

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Metal sensor proteins: nature's metalloregulated allosteric switches.

5 July 2018

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A complex thiolate switch regulates the Bacillus subtilis organic peroxide sensor OhrR.

5 July 2018

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Zinc-responsive regulation of alternative ribosomal protein genes in Streptomyces coelicolor involves zur and sigmaR.

5 July 2018

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Nickel-specific response in the transcriptional regulator, Escherichia coli NikR.

5 July 2018

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Conformational studies of the manganese transport regulator (MntR) from Bacillus subtilis using deuterium exchange mass spectrometry.

5 July 2018

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The X-ray crystal structure of PA1607 from Pseudomonas aureginosa at 1.9 A resolution--a putative transcription factor

5 July 2018

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Development of genomic array footprinting for identification of conditionally essential genes in Streptococcus pneumoniae

5 July 2018

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Functional specialization within the Fur family of metalloregulators

5 July 2018

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Crystal structure and function of the zinc uptake regulator FurB from Mycobacterium tuberculosis

5 July 2018

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Metal binding studies and EPR spectroscopy of the manganese transport regulator MntR

5 July 2018

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Global analysis of the Mycobacterium tuberculosis Zur (FurB) regulon

5 July 2018

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Genome sequence of Avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6.

5 July 2018

1 reference

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The ABC transporter protein OppA provides protection against experimental Yersinia pestis infection

5 July 2018

1 reference

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Regulation of virulence by members of the MarR/SlyA family

5 July 2018

1 reference

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Ligand-responsive transcriptional regulation by members of the MarR family of winged helix proteins.

5 July 2018

1 reference

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Micronutrients in childhood and the influence of subclinical inflammation

5 July 2018

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1.2 Angstroms crystal structure of the S. pneumoniae PhtA histidine triad domain a novel zinc binding fold.

5 July 2018

1 reference

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Structural determinants of metal selectivity in prokaryotic metal-responsive transcriptional regulators

5 July 2018

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ATP-binding cassette transporters are targets for the development of antibacterial vaccines and therapies

5 July 2018

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New expression system tightly controlled by zinc availability in Lactococcus lactis.

5 July 2018

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A Metal–Ligand-mediated Intersubunit Allosteric Switch in Related SmtB/ArsR Zinc Sensor Proteins

5 July 2018

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Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR

5 July 2018

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Comparative genomics of bacterial zinc regulons: enhanced ion transport, pathogenesis, and rearrangement of ribosomal proteins

5 July 2018

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Involvement of the adc operon and manganese homeostasis in Streptococcus gordonii biofilm formation

5 July 2018

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Structural elements of metal selectivity in metal sensor proteins.

5 July 2018

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Crystal Structure of Enterococcus faecalis SlyA-like Transcriptional Factor

5 July 2018

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Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors

5 July 2018

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Allosteric negative regulation of smt O/P binding of the zinc sensor, SmtB, by metal ions: a coupled equilibrium analysis.

5 July 2018

1 reference

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Crystal structure of the MexR repressor of the mexRAB-oprM multidrug efflux operon of Pseudomonas aeruginosa

5 July 2018

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The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution

5 July 2018

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ZitB (YbgR), a member of the cation diffusion facilitator family, is an additional zinc transporter in Escherichia coli

5 July 2018

1 reference

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Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis

5 July 2018

1 reference

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Identification and characterization of a novel family of pneumococcal proteins that are protective against sepsis

5 July 2018

1 reference

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Protein backbone angle restraints from searching a database for chemical shift and sequence homology

5 July 2018

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The adc locus, which affects competence for genetic transformation in Streptococcus pneumoniae, encodes an ABC transporter with a putative lipoprotein homologous to a family of streptococcal adhesins

5 July 2018

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The ZnuABC high-affinity zinc uptake system and its regulator Zur in Escherichia coli

5 July 2018

1 reference

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Regulation of competence for genetic transformation in Streptococcus pneumoniae

5 July 2018

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Competence and virulence of Streptococcus pneumoniae: Adc and PsaA mutants exhibit a requirement for Zn and Mn resulting from inactivation of putative ABC metal permeases

5 July 2018

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Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinase

5 July 2018

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1H, 13C and 15N chemical shift referencing in biomolecular NMR

5 July 2018

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

5 July 2018

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Trace elements in human body fluids and tissues

5 July 2018

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Geometry of interaction of metal ions with histidine residues in protein structures

5 July 2018

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Energetics of allosteric negative coupling in the zinc sensor S. aureus CzrA.

5 July 2018

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Protective capacities of cell surface-associated proteins of Streptococcus suis mutants deficient in divalent cation-uptake regulators.

28 October 2018

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Pneumococcal histidine triad proteins are regulated by the Zn2+-dependent repressor AdcR and inhibit complement deposition through the recruitment of complement factor H.

28 October 2018

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pK values of the ionizable groups of proteins

28 October 2018

1 reference

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Kinetics of metal binding by the toxic metal-sensing transcriptional repressor Staphylococcus aureus pI258 CadC.

28 October 2018

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Individual metal ligands play distinct functional roles in the zinc sensor Staphylococcus aureus CzrA.

28 October 2018

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Structure of an OhrR-ohrA operator complex reveals the DNA binding mechanism of the MarR family

28 October 2018

1 reference

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Mutational analysis of the adcCBA genes in Streptococcus gordonii biofilm formation

28 October 2018

1 reference

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Variability in the pKa of histidine side-chains correlates with burial within proteins

28 October 2018

1 reference

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Structural characterization of distinct alpha3N and alpha5 metal sites in the cyanobacterial zinc sensor SmtB.

28 October 2018

1 reference

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Characterization of the metal receptor sites in Escherichia coli Zur, an ultrasensitive zinc(II) metalloregulatory protein.

28 October 2018

1 reference

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Characterization of indo-1 and quin-2 as spectroscopic probes for Zn2(+)-protein interactions

28 October 2018

1 reference

12 December 2020

The zinc-responsive regulator Zur and its control of the znu gene cluster encoding the ZnuABC zinc uptake system in Escherichia coli

1 reference

12 December 2020

The zinc metalloregulatory protein Synechococcus PCC7942 SmtB binds a single zinc ion per monomer with high affinity in a tetrahedral coordination geometry

1 reference

12 December 2020

The Crystal Structure of the Transcriptional Regulator HucR from Deinococcus radiodurans Reveals a Repressor Preconfigured for DNA Binding

1 reference

12 December 2020

An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus

1 reference

12 December 2020

A PerR-regulated metal transporter (PmtA) is an interface between oxidative stress and metal homeostasis in Streptococcus pyogenes

1 reference

12 December 2020

Analysis of the structural consensus of the zinc coordination centers of metalloprotein structures

1 reference

12 December 2020

10.1016/J.JMB.2010.08.030

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804771%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20804771%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

20804771

1 reference