Cell cholesterol modulates metalloproteinase-dependent shedding of low-density lipoprotein receptor-related protein-1 (LRP-1) and clearance function. (Q34180389)

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English	Cell cholesterol modulates metalloproteinase-dependent shedding of low-density lipoprotein receptor-related protein-1 (LRP-1) and clearance function.	scientific article

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29 January 2020

Cell cholesterol modulates metalloproteinase-dependent shedding of low-density lipoprotein receptor-related protein-1 (LRP-1) and clearance function (English)

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Ludovic D'Auria

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Stephane Dedieu

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Charlotte Selvais

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Gwenn Perrot

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Pascale Lemoine

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Hideaki Nagase

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Patrick Henriet

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Pierre J Courtoy

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Hervé Emonard

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Donatienne Tyteca

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29 January 2020

Etienne Marbaix

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25 April 2011

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29 January 2020

2770-2781

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29 January 2020

Emerging concepts in the regulation of membrane-type 1 matrix metalloproteinase activity

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5 July 2018

LRP1 shedding in human brain: roles of ADAM10 and ADAM17.

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5 July 2018

Insulin induces the low density lipoprotein receptor-related protein 1 (LRP1) degradation by the proteasomal system in J774 macrophage-derived cells

1 reference

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5 July 2018

ADAM10 is the constitutive functional sheddase of CD44 in human melanoma cells.

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5 July 2018

The ADAM metalloproteinases

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5 July 2018

LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies

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5 July 2018

Cellular roles of ADAM12 in health and disease.

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5 July 2018

LRP-1 silencing prevents malignant cell invasion despite increased pericellular proteolytic activities

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5 July 2018

Cellular cholesterol trafficking and compartmentalization

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5 July 2018

The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events.

1 reference

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5 July 2018

Tissue-type plasminogen activator-mediated shedding of astrocytic low-density lipoprotein receptor-related protein increases the permeability of the neurovascular unit.

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5 July 2018

Shedding light on ADAM metalloproteinases

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5 July 2018

Nectin-4, a new serological breast cancer marker, is a substrate for tumor necrosis factor-alpha-converting enzyme (TACE)/ADAM-17.

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5 July 2018

Regulation of matrix metalloproteinase (MMP) activity by the low-density lipoprotein receptor-related protein (LRP). A new function for an "old friend".

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5 July 2018

The low density lipoprotein receptor-related protein (LRP) is a novel beta-secretase (BACE1) substrate.

1 reference

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5 July 2018

Regulation of matrix metalloproteinase-9/gelatinase B expression and activation by ovarian steroids and LEFTY-A/endometrial bleeding-associated factor in the human endometrium

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5 July 2018

ADAM12 is selectively overexpressed in human glioblastomas and is associated with glioblastoma cell proliferation and shedding of heparin-binding epidermal growth factor

1 reference

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5 July 2018

Low density lipoprotein receptor-related protein mediates endocytic clearance of pro-MMP-2.TIMP-2 complex through a thrombospondin-independent mechanism

1 reference

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5 July 2018

Cholesterol depletion increases membrane stiffness of aortic endothelial cells

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5 July 2018

The mechanism of cleavage of EGFR ligands induced by inflammatory cytokines in gastric cancer cells

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5 July 2018

ADAM binding protein Eve-1 is required for ectodomain shedding of epidermal growth factor receptor ligands

1 reference

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5 July 2018

Cellular cholesterol regulates MT1 MMP dependent activation of MMP 2 via MEK-1 in HT1080 fibrosarcoma cells

1 reference

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5 July 2018

Depletion of cellular cholesterol and lipid rafts increases shedding of CD30.

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5 July 2018

The low density lipoprotein receptor-related protein is a motogenic receptor for plasminogen activator inhibitor-1.

1 reference

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5 July 2018

The low density lipoprotein receptor-related protein LRP is regulated by membrane type-1 matrix metalloproteinase (MT1-MMP) proteolysis in malignant cells

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5 July 2018

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

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5 July 2018

PACSIN3 binds ADAM12/meltrin alpha and up-regulates ectodomain shedding of heparin-binding epidermal growth factor-like growth factor

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5 July 2018

Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE)

1 reference

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5 July 2018

v-Src induces Shc binding to tyrosine 63 in the cytoplasmic domain of the LDL receptor-related protein 1.

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5 July 2018

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

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5 July 2018

E. coli expression of TIMP-4 and comparative kinetic studies with TIMP-1 and TIMP-2: insights into the interactions of TIMPs and matrix metalloproteinase 2 (gelatinase A)

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5 July 2018

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5 July 2018

Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolae

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5 July 2018

Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.

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5 July 2018

Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion

1 reference

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5 July 2018

Characterization of the soluble form of the low density lipoprotein receptor-related protein (LRP)

1 reference

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5 July 2018

Soluble low density lipoprotein receptor-related protein (LRP) circulates in human plasma

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5 July 2018

The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3.

1 reference

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5 July 2018

Cellular cholesterol efflux mediated by cyclodextrins

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5 July 2018

E1a induces the expression of epithelial characteristics

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5 July 2018

LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation

1 reference

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5 July 2018

Three unrelated sphingomyelin analogs spontaneously cluster into plasma membrane micrometric domains.

1 reference

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28 October 2018

Metalloproteinase-dependent shedding of low-density lipoprotein receptor-related protein-1 ectodomain decreases endocytic clearance of endometrial matrix metalloproteinase-2 and -9 at menstruation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470721

28 October 2018

Catalytic properties of ADAM12 and its domain deletion mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470721

28 October 2018

Insulin facilitates the hepatic clearance of plasma amyloid beta-peptide (1 40) by intracellular translocation of low-density lipoprotein receptor-related protein 1 (LRP-1) to the plasma membrane in hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470721

28 October 2018

The low-density lipoprotein receptor-related protein-1 associates transiently with lipid rafts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470721

28 October 2018

Response of matrix metalloproteinases and tissue inhibitors of metalloproteinases messenger ribonucleic acids to ovarian steroids in human endometrial explants mimics their gene- and phase-specific differential control in vivo

1 reference

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28 October 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470721

28 October 2018

MT1-MMP expression promotes tumor growth and angiogenesis through an up-regulation of vascular endothelial growth factor expression.

1 reference

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28 October 2018

Involvement of fibronectin type II repeats in the efficient inhibition of gelatinases A and B by long-chain unsaturated fatty acids.

1 reference

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28 October 2018

TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TS5)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21518850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-kappaB ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/21518850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The YSNSG cyclopeptide derived from tumstatin inhibits tumor angiogenesis by down-regulating endothelial cell migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/21518850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ADAM-12 (meltrin alpha) is involved in chondrocyte proliferation via cleavage of insulin-like growth factor binding protein 5 in osteoarthritic cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/21518850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Human ADAM 12 Protease by the Prodomain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21518850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of the alpha(2)-macroglobulin receptor and the receptor associated protein in normal human endometrium and endometrial carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21518850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular Profiling of ADAM12 in Human Bladder Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21518850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular trafficking of cholesterol monitored with a cyclodextrin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21518850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of alpha-, beta- and gamma-cyclodextrins on human erythrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21518850

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1096/FJ.10-169508

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29 January 2020

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Europe PubMed Central

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29 January 2020

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29 January 2020

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