Rho signals to cell growth and apoptosis (Q34180592)

31 July 2017

Rho signals to cell growth and apoptosis (English)

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31 July 2017

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Salvador Aznar Benitah

object named as

Aznar S

series ordinal

1

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author name string

Lacal JC

series ordinal

2

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PubMed ID

11248412

31 July 2017

language of work or name

English

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publication date

1 April 2001

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31 July 2017

10

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inferred from page(s)

published in

Cancer Letters

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31 July 2017

165

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31 July 2017

1

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31 July 2017

1-10

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Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Rho GTPases and signaling networks

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Searching new targets for anticancer drug design: the families of Ras and Rho GTPases and their effectors

1 reference

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7 January 2021

Ras and Rho GTPases: a family reunion

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Activation of ternary complex factor Elk-1 by stress-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Transcription factor ATF2 regulation by the JNK signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Phosphorylation of c-jun mediated by MAP kinases.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

The small GTP-binding protein Rho links G protein-coupled receptors and Galpha12 to the serum response element and to cellular transformation.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Exogenous C2-ceramide activates c-fos serum response element via Rac-dependent signalling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Signal-regulated activation of serum response factor is mediated by changes in actin dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Regulation of STAT3 by direct binding to the Rac1 GTPase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Rho GTPase signaling in inflammation and transformation.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Genomic analysis of metastasis reveals an essential role for RhoC

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Rho GTPases are over-expressed in human tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

The Ras family of GTPases in cancer cell invasion.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Rho proteins induce metastatic properties in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

The CDC42-specific inhibitor derived from ACK-1 blocks v-Ha-Ras-induced transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

A role for Rho in Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

An essential role for Rac in Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

A domain containing the Cdc42/Rac interactive binding (CRIB) region of p65PAK inhibits transcriptional activation and cell transformation mediated by the Ras-Rac pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

A role for Pak protein kinases in Schwann cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells. Evidence for a Pak-independent signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Urokinase plasminogen activator/urokinase-specific surface receptor expression and matrix invasion by breast cancer cells requires constitutive p38alpha mitogen-activated protein kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Regulation of urokinase receptor transcription by Ras- and Rho-family GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Fibronectin matrix regulates activation of RHO and CDC42 GTPases and cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

A region between -141 and -61 bp containing a proximal AP-1 is essential for constitutive expression of urokinase-type plasminogen activator receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Identification of a novel nuclear factor-kappaB sequence involved in expression of urokinase-type plasminogen activator receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Role of the IkappaB kinase complex in oncogenic Ras- and Raf-mediated transformation of rat liver epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Raf induces NF-kappaB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

NF-kappa B is required for H-ras oncogene induced abnormal cell proliferation and tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Dependence of Dbl and Dbs transformation on MEK and NF-kappaB activation

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Ral and Rho-dependent activation of phospholipase D in v-Raf-transformed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Transformation mediated by RhoA requires activity of ROCK kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

An EGF receptor/Ral-GTPase signaling cascade regulates c-Src activity and substrate specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Activation of serum response factor by RhoA is mediated by the nuclear factor-kappaB and C/EBP transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Activation of SRF-regulated chromosomal templates by Rho-family GTPases requires a signal that also induces H4 hyperacetylation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Prenylation of RhoB is required for its cell transforming function but not its ability to activate serum response element-dependent transcription

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https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Effector domain mutants of Rho dissociate cytoskeletal changes from nuclear signaling and cellular transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Rho-regulated signals induce apoptosis in vitro and in vivo by a p53-independent, but Bcl2 dependent pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Vav regulates peptide-specific apoptosis in thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Enhanced apoptosis in the thymus of transgenic mice expressing constitutively activated forms of human Rac2GTPase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Apoptosis induced by Rac GTPase correlates with induction of FasL and ceramides production

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Proteolytic activation of PKN by caspase-3 or related protease during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Inhibition of Akt and its anti-apoptotic activities by tumor necrosis factor-induced protein kinase C-related kinase 2 (PRK2) cleavage

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

The small GTPase Cdc42 initiates an apoptotic signaling pathway in Jurkat T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

Fas-induced apoptosis is mediated by activation of a Ras and Rac protein-regulated signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900412-8

7 January 2021

10.1016/S0304-3835(01)00412-8

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

11248412