Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010. (Q34181630)

31 July 2017

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title

Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010. (English)

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31 July 2017

14

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31 July 2017

52

Henk van Loveren

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Jan van Benthem

5

Jan van Benthem

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Jos Bessems

Jos Bessems

13

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Alexandre Angers-Loustau

Alexandre Angers-Loustau

8

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Guillermo Repetto

Guillermo Repetto

44

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Andrew Worth

Andrew Worth

54

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Mathieu Vinken

Mathieu Vinken

53

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Alan Boobis

Alan Boobis

15

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Emilio Benfenati

11

Emilio Benfenati

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31 July 2017

30

Jos Kleinjans

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46

Greet Schoeters

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2

David Basketter

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10

Anna Bal-Price

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4

Olavi Pelkonen

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27

Ursula Gundert-Remy

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20

Sandra Coecke

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31 July 2017

Sarah Adler

1

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Stuart Creton

3

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31 July 2017

Jan van Benthem

5

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31 July 2017

Valérie Zuang

6

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31 July 2017

Klaus Ejner Andersen

7

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31 July 2017

Aynur Aptula

9

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Ulrike Bernauer

12

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Esther Brandon

16

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31 July 2017

Susanne Bremer

17

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31 July 2017

Thomas Broschard

18

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31 July 2017

Silvia Casati

19

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31 July 2017

Raffaella Corvi

21

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31 July 2017

Mark Cronin

22

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31 July 2017

George Daston

23

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31 July 2017

Wolfgang Dekant

24

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31 July 2017

Susan Felter

25

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31 July 2017

Elise Grignard

26

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31 July 2017

Tuula Heinonen

28

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31 July 2017

Ian Kimber

29

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31 July 2017

Hannu Komulainen

31

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31 July 2017

Reinhard Kreiling

32

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31 July 2017

Joachim Kreysa

33

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31 July 2017

Sofia Batista Leite

34

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31 July 2017

George Loizou

35

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31 July 2017

Gavin Maxwell

36

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31 July 2017

Paolo Mazzatorta

37

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31 July 2017

Sharon Munn

38

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31 July 2017

Stefan Pfuhler

39

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31 July 2017

Pascal Phrakonkham

40

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31 July 2017

Aldert Piersma

41

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31 July 2017

Albrecht Poth

42

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31 July 2017

Pilar Prieto

43

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31 July 2017

Vera Rogiers

45

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31 July 2017

Michael Schwarz

47

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31 July 2017

Rositsa Serafimova

48

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31 July 2017

Hanna Tähti

49

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31 July 2017

Emanuela Testai

50

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31 July 2017

Joost van Delft

51

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31 July 2017

José-Manuel Zaldivar

55

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31 July 2017

publication date

1 May 2011

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31 July 2017

published in

Archives of Toxicology

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31 July 2017

volume

85

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31 July 2017

issue

5

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31 July 2017

page(s)

367-485

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International prevalidation studies of the EpiDerm 3D human reconstructed skin micronucleus (RSMN) assay: transferability and reproducibility

31 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

First steps in establishing a developmental toxicity test method based on human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A review of imaging agent development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Reactivity profiling: covalent modification of single nucleophile peptides for skin sensitization risk assessment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Molecular modeling of blood-brain barrier nutrient transporters: in silico basis for evaluation of potential drug delivery to the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vitro zonation and toxicity in a hepatocyte bioreactor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

21 January 2018

What do we Mean by Dose

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Comparison of gene expression profiles in BALB/c 3T3 transformed foci exposed to tumor promoting agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Dermal sensitization quantitative risk assessment (QRA) for fragrance ingredients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Haptens, prohaptens and prehaptens, or electrophiles and proelectrophiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Validation of negligible depletion solid-phase microextraction as a tool to determine tissue/blood partition coefficients for semivolatile and nonvolatile organic chemicals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Expectations for transgenic rodent cancer bioassay models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Dimethandrolone undecanoate: a new potent orally active androgen with progestational activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vitro developmental toxicology assays: A review of the state of the science of rodent and zebrafish whole embryo culture and embryonic stem cell assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Future of toxicology-metabolic activation and drug design: challenges and opportunities in chemical toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Metabolism and toxicity of drugs. Two decades of progress in industrial drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Application of in vitro neurotoxicity testing for regulatory purposes: Symposium III summary and research needs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Phase III interlaboratory study of FETAX. Part 3. FETAX validation using 12 compounds with and without an exogenous metabolic activation system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

4.7 Biological modeling as a method for data evaluation and integration in toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The acquisition and application of absorption, distribution, metabolism, and excretion (ADME) data in agricultural chemical safety assessments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The human repeated insult patch test in the 21st century: a commentary

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Methyldibromoglutaronitrile: skin sensitization and quantitative risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Evaluation of the skin sensitizing potency of chemicals by using the existing methods and considerations of relevance for elicitation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The local lymph node assay and the assessment of relative potency: status of validation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Does irritation potency contribute to the skin sensitization potency of contact allergens?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Skin irritation and sensitization: mechanisms and new approaches for risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Updating the skin sensitization in vitro data assessment paradigm in 2009.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Alternatives to the carcinogenicity bioassay: in silico methods, and the in vitro and in vivo mutagenicity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In silico approaches to predicting cancer potency for risk assessment of genotoxic impurities in drug substances

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Interlaboratory assessment of the GreenScreen HC GADD45a-GFP genotoxicity screening assay: an enabling study for independent validation as an alternative method.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A pre-validation transferability study of the GreenScreen HC GADD45a-GFP assay with a metabolic activation system (S9).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

REPDOSE: A database on repeated dose toxicity studies of commercial chemicals--A multifunctional tool

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vitro assessment of AhR-mediated activities of TCDD in mixture with humic substances

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The contribution of in vitro toxicity data in hazard and risk assessment: current limitations and future perspectives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Biokinetic modeling and in vitro-in vivo extrapolations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The need for a new toxicity testing and risk analysis paradigm to implement REACH or any other large scale testing initiative

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Toxicity testing in the 21st century: using the new toxicity testing paradigm to create a taxonomy of adverse effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats: possible implications for toxicogenomics use of in vitro systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Kinetic glutathione chemoassay to quantify thiol reactivity of organic electrophiles--application to alpha,beta-unsaturated ketones, acrylates, and propiolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

An analysis of exposure rate effects for benzene using a physiologically based pharmacokinetic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Optimal design for a study of butadiene toxicokinetics in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

PBPK modelling of inter-individual variability in the pharmacokinetics of environmental chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

IPCS framework for analyzing the relevance of a cancer mode of action for humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

IPCS framework for analyzing the relevance of a noncancer mode of action for humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Application of key events analysis to chemical carcinogens and noncarcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A data-based assessment of alternative strategies for identification of potential human cancer hazards

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Improving the applicability of (Q)SARs for percutaneous penetration in regulatory risk assessment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Effects and uptake of gold nanoparticles deposited at the air-liquid interface of a human epithelial airway model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Consumer product in vitro digestion model: Bioaccessibility of contaminants and its application in risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Development of a zebrafish embryo teratogenicity assay and quantitative prediction model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The development of new concepts for assessing reproductive toxicity applicable to large scale toxicological programmes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Quantitation of rat embryonic development in vitro: A morphological scoring system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Cord blood stem and progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Update on national toxicology program (NTP) assays with genetically altered or "transgenic" mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Embryonic stem cell test remastered: comparison between the validated EST and the new molecular FACS-EST for assessing developmental toxicity in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Development of a new screening assay to identify proteratogenic substances using zebrafish danio rerio embryo combined with an exogenous mammalian metabolic activation system (mDarT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A human stem cell-based model for identifying adverse effects of organic and inorganic chemicals on the developing nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vitro tests to evaluate immunotoxicity: a preliminary study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Maintenance and characterization of lymphocytes in human long term bone marrow cultures to study immunotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Exposure based waiving: the application of the toxicological threshold of concern (TTC) to inhalation exposure for aerosol ingredients in consumer products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Modelling of the blood-brain barrier in drug discovery and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Identification of small molecules from human embryonic stem cells using metabolomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Endless possibilities: stem cells and the vision for toxicology testing in the 21st century

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Struggles for equivalence: in vitro developmental toxicity model evolution in pharmaceuticals in 2006.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Global QSAR models of skin sensitisers for regulatory purposes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A tiered approach to threshold of regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Rapid and simple kinetics screening assay for electrophilic dermal sensitizers using nitrobenzenethiol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Identification of toxicological biomarkers of di(2-ethylhexyl) phthalate in proteins secreted by HepG2 cells using proteomic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Quantitative interpretation of human biomonitoring data

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Human carcinogenic risk evaluation: an alternative approach to the two-year rodent bioassay

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Comparison of MC4PC and MDL-QSAR rodent carcinogenicity predictions and the enhancement of predictive performance by combining QSAR models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A tiered approach to life stages testing for agricultural chemical safety assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Use of IL-18 production in a human keratinocyte cell line to discriminate contact sensitizers from irritants and low molecular weight respiratory allergens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

ECVAM retrospective validation of in vitro micronucleus test (MNT)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Estimation of toxic hazard—A decision tree approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Computational approaches for predicting CYP-related metabolism properties in the screening of new drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Development of a method for assessing micronucleus induction in a 3D human skin model (EpiDerm).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The prediction of drug metabolism, tissue distribution, and bioavailability of 50 structurally diverse compounds in rat using mechanism-based absorption, distribution, and metabolism prediction tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Microarray analyses and molecular profiling of steatosis induction in immortalized human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Cytochrome p450 in silico: an integrative modeling approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Use of a low-density microarray for studying gene expression patterns induced by hepatotoxicants on primary cultures of rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Estimation of systemic toxicity of acrylamide by integration of in vitro toxicity data with kinetic simulations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Hapten-protein binding: from theory to practical application in the in vitro prediction of skin sensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Cytometric analysis for drug-induced steatosis in HepG2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A cancer risk assessment of di(2-ethylhexyl)phthalate: application of the new U.S. EPA Risk Assessment Guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Application of toxicogenomics to study mechanisms of genotoxicity and carcinogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Characterization and interlaboratory comparison of a gene expression signature for differentiating genotoxic mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A review of the electrophilic reaction chemistry involved in covalent DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Identification of mechanisms of toxic action for skin sensitisation using a SMARTS pattern based approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

International Commission for Protection Against Environmental Mutagens and Carcinogens. Use of SAR in computer-assisted prediction of carcinogenicity and mutagenicity of chemicals by the TOPKAT program

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Cancer epigenomics: DNA methylomes and histone-modification maps

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A category approach for reproductive effects of phthalates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A review of the scientific basis for uncertainty factors for use in quantitative risk assessment for the induction of allergic contact dermatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Application of the risk assessment paradigm to the induction of allergic contact dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Refining the threshold of toxicological concern (TTC) for risk prioritization of trace chemicals in food.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A gene expression biomarker provides early prediction and mechanistic assessment of hepatic tumor induction by nongenotoxic chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Interlaboratory evaluation of genomic signatures for predicting carcinogenicity in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

New public QSAR model for carcinogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Enhancing the predictive validity of Frog Embryo Teratogenesis Assay--Xenopus (FETAX).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Novel tissue engineered tubular heart tissue for in vitro pharmaceutical toxicity testing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Comparison of the sensitivities of the Buehler test and the guinea pig maximization test for predictive testing of contact allergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

FDA perspectives on the use of teratology data for human risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Assessment of a recombinant androgen receptor binding assay: initial steps towards validation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Screening for (anti)androgenic properties using a standard operation protocol based on the human stably transfected androgen sensitive PALM cell line. First steps towards validation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Assessment of a robust model protocol with accelerated throughput for a human recombinant full length estrogen receptor-alpha binding assay: protocol optimization and intralaboratory assay performance as initial steps towards validation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Progress on the development of human in vitro dendritic cell based assays for assessment of the sensitizing potential of a compound

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vitro models for the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

True prediction of lowest observed adverse effect levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Understanding fragrance allergy using an exposure-based risk assessment approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Development of a peptide reactivity assay for screening contact allergens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Quantification of chemical peptide reactivity for screening contact allergens: a classification tree model approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Investigation of peptide reactivity of pro-hapten skin sensitizers using a peroxidase-peroxide oxidation system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Physiologically Based Pharmacokinetic Modeling: Principles and Applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Effects of plasticizers and their mixtures on estrogen receptor and thyroid hormone functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Xenobiotic metabolism in human skin and 3D human skin reconstructs: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Cytotoxicity and genotoxicity in human lung epithelial A549 cells caused by airborne volatile organic compounds emitted from pine wood and oriented strand boards

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Human hepatocytes as a tool for studying toxicity and drug metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Proposal for a risk assessment methodology for skin sensitization based on sensitization potency data

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Cytokines and Langerhans cell mobilisation in mouse and man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Stem cell-derived hepatocytes and their use in toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vitro human T cell sensitization to haptens by monocyte-derived dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vitro-in vivo extrapolation: estimation of human serum concentrations of chemicals equivalent to cytotoxic concentrations in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Factors influencing nominal effective concentrations of chemical compounds in vitro: cell concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Rat toxicogenomic study reveals analytical consistency across microarray platforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Improving prediction of chemical carcinogenicity by considering multiple mechanisms and applying toxicogenomic approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Recent advances in biomedical applications of accelerator mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

New strategy for alerting central nervous system toxicity: Integration of blood-brain barrier toxicity and permeability in neurotoxicity assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In Vitro Techniques for the Assessment of Neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

High throughput adjustable 96-well plate assay for androgen receptor binding: a practical approach for EDC screening using the chimpanzee AR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

High-specificity and high-sensitivity genotoxicity assessment in a human cell line: validation of the GreenScreen HC GADD45a-GFP genotoxicity assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Generation and characterization of T-helper cells by primary in vitro sensitization using Langerhans cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Lazy structure-activity relationships (lazar) for the prediction of rodent carcinogenicity and Salmonella mutagenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Toward more useful in vitro toxicity data with measured free concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Integrating (Q)SAR models, expert systems and read-across approaches for the prediction of developmental toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Modification of cell-surface thiols elicits activation of human monocytic cell line THP-1: possible involvement in effect of haptens 2,4-dinitrochlorobenzene and nickel sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A cell-based in vitro alternative to identify skin sensitizers by gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Understanding mechanisms of toxicity: insights from drug discovery research

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Methods for predicting in vivo pharmacokinetics using data from in vitro assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Identification of a gene expression profile that discriminates indirect-acting genotoxins from direct-acting genotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Intralaboratory and interlaboratory evaluation of the EpiDerm 3D human reconstructed skin micronucleus (RSMN) assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Xenobiotic metabolism gene expression in the EpiDermin vitro 3D human epidermis model compared to human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Proposal for a tiered approach to developmental toxicity testing for veterinary pharmaceutical products for food-producing animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

New cytochrome P450 mechanisms: implications for understanding molecular basis for drug toxicity at the level of the cytochrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Comparison of the standard and reduced pH Syrian hamster embryo (SHE) cell in vitro transformation assays in predicting the carcinogenic potential of chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vitro thyroid hormone-disrupting activity in effluents and surface waters in Thailand

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Assessment of the genotoxicity of S9-generated metabolites using the GreenScreen HC GADD45a-GFP assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A framework for assessing inter-individual variability in pharmacokinetics using virtual human populations and integrating general knowledge of physical chemistry, biology, anatomy, physiology and genetics: A tale of 'bottom-up' vs 'top-down' recogn

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

How can structural similarity analysis help in category formation?§

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Inter-laboratory comparison of human renal proximal tubule (HK-2) transcriptome alterations due to Cyclosporine A exposure and medium exhaustion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

QSAR models for reproductive toxicity and endocrine disruption in regulatory use--a preliminary investigation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Diagnosis of drug-induced renal tubular toxicity using global gene expression profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Modelling and PBPK simulation in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A future approach to measuring relative skin sensitising potency: a proposal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Effects of pharmaceuticals and other active chemicals at biological targets: mechanisms, interactions, and integration into PB-PK/PD models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Regulatory classification of substances oxidized to skin sensitizers on exposure to air.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Differential susceptibilities of Holtzman and Sprague-Dawley rats to fetal death and placental dysfunction induced by 2,3,7,8-teterachlorodibenzo-p-dioxin (TCDD) despite the identical primary structure of the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Feasibility study to support a threshold of sensitization concern concept in risk assessment based on human data

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Preclinical assessment of cardiac toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Applications of microarrays with toxicologically relevant genes (tox genes) for the evaluation of chemical toxicants in Sprague Dawley rats in vivo and human hepatocytes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vivo hepatotoxicity study of rats in comparison with in vitro hepatotoxicity screening system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Microvalve-assisted patterning platform for measuring cellular dynamics based on 3D cell culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The murine local lymph node assay: a commentary on collaborative studies and new directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Cytokines and chemokines in the initiation and regulation of epidermal Langerhans cell mobilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The local lymph node assay and skin sensitization: a cut-down screen to reduce animal requirements?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Further analysis of Ames-negative rodent carcinogens that are only genotoxic in mammalian cells in vitro at concentrations exceeding 1 mM, including retesting of compounds of concern.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens III. Appropriate follow-up testing in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens II. Further analysis of mammalian cell results, relative predictivity and tumour profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Oxidative stress and oxidative damage in carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

International Commission for Protection Against Environmental Mutagens and Carcinogens. Approaches to SAR in carcinogenesis and mutagenesis. Prediction of carcinogenicity/mutagenicity using MULTI-CASE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

o,p'-DDT and its metabolites inhibit progesterone-dependent responses in yeast and human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The influence of modes of action and physicochemical properties of chemicals on the correlation between in vitro and acute fish toxicity data

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Comparison of the skin sensitizing potential of unsaturated compounds as assessed by the murine local lymph node assay (LLNA) and the guinea pig maximization test (GPMT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Toxicity testing in the 21st century: a vision and a strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Threshold of toxicological concern (TTC) in food safety assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Structure-based thresholds of toxicological concern (TTC): guidance for application to substances present at low levels in the diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The threshold of toxicological concern concept in risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Analysis, interpretation, and extrapolation of dermal permeation data using diffusion-based mathematical models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In silico techniques for the study and prediction of xenobiotic metabolism: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Estrogenic in vitro assay on mouse embryonic Leydig cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Gene markers in dendritic cells unravel pieces of the skin sensitization puzzle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The use of accelerator mass spectrometry to obtain early human ADME/PK data

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Development of an in vitro test battery for assessing chemical effects on bovine germ cells under the ReProTect umbrella

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Characterization of DNA reactive and non-DNA reactive anticancer drugs by gene expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

An artificial liver sinusoid with a microfluidic endothelial-like barrier for primary hepatocyte culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

An engineered 3D blood-testis barrier model for the assessment of reproductive toxicity potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The antibiotic streptomycin assessed in a battery of in vitro tests for reproductive toxicology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Human primary renal cells as a model for toxicity assessment of chemo-therapeutic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Toxicogenomics: overview and potential applications for the study of non-covalent DNA interacting chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Development of a screening approach to interpret human biomonitoring data on volatile organic compounds: reverse dosimetry on biomonitoring data for trichloroethylene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Mechanisms of nongenotoxic carcinogenesis and assessment of the human hazard.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Epigenomics and breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Advances in chemical carcinogenesis: a historical review and prospective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Effects of currently used pesticides in the AhR-CALUX assay: comparison between the human TV101L and the rat H4IIE cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A new view of carcinogenesis and an alternative approach to cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Transferability and inter-laboratory variability assessment of the in vitro bovine oocyte maturation (IVM) test within ReProTect

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Transcriptomics analysis of retinoic acid embryotoxicity in rat postimplantation whole embryo culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Computational toxicology of chloroform: reverse dosimetry using Bayesian inference, Markov chain Monte Carlo simulation, and human biomonitoring data.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Characterization of drug metabolites and cytotoxicity assay simultaneously using an integrated microfluidic device

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

An expert system approach to the assessment of hepatotoxic potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Profiling chemicals based on chronic toxicity results from the U.S. EPA ToxRef Database

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

T-cell recognition of chemicals, protein allergens and drugs: towards the development of in vitro assays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Medicine. Building better mouse models for studying cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Gene expression profiling in primary mouse hepatocytes discriminates true from false-positive genotoxic compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Combined Use of MC4PC, MDL-QSAR, BioEpisteme, Leadscope PDM, and Derek for Windows Software to Achieve High-Performance, High-Confidence, Mode of Action-Based Predictions of Chemical Carcinogenesis in Rodents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Prediction of chemical toxicity with local support vector regression and activity-specific kernels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Integration of structure-activity relationship and artificial intelligence systems to improve in silico prediction of ames test mutagenicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Modeling oral rat chronic toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Contact allergy, irritancy and 'danger'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Biologically motivated computational modeling: contribution to risk assessment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Brain drug targeting: a computational approach for overcoming blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Identification of the structural requirements for mutagenicity by incorporating molecular flexibility and metabolic activation of chemicals I: TA100 model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Identifying the structural requirements for chromosomal aberration by incorporating molecular flexibility and metabolic activation of chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Dendritic cells: specialized and regulated antigen processing machines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Steroid receptor profiling of vinclozolin and its primary metabolites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The development of an innervated epithelial barrier model using a human corneal cell line and ND7/23 sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Placental transport and in vitro effects of Bisphenol A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Use of metabonomics to identify impaired fatty acid metabolism as the mechanism of a drug-induced toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Placental passage of benzoic acid, caffeine, and glyphosate in an ex vivo human perfusion system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Thresholds of toxicological concern based on structure-activity relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The Threshold of Toxicological Concern (TTC) in risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Computational toxicology in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Developmental expression of drug metabolizing enzymes and transporter proteins in human placenta and fetal tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The human placenta--an alternative for studying foetal exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Evaluation of the protein binding ratio of drugs by a micro-scale ultracentrifugation method

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The Nrf2-Keap1-ARE toxicity pathway as a cellular sensor for skin sensitizers--functional relevance and a hypothesis on innate reactions to skin sensitizers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Skin sensitizers induce antioxidant response element dependent genes: application to the in vitro testing of the sensitization potential of chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Filling the concept with data: integrating data from different in vitro and in silico assays on skin sensitizers to explore the battery approach for animal-free skin sensitization testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Whole body pharmacokinetic models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Whole-body physiologically based pharmacokinetic models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Predictive toxicogenomics approaches reveal underlying molecular mechanisms of nongenotoxic carcinogenicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Prediction of non-genotoxic carcinogenesis in rats using changes in gene expression following acute dosing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Safety assessment of personal care products/cosmetics and their ingredients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Concordance of the toxicity of pharmaceuticals in humans and in animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vitro intestinal lead uptake and transport in relation to speciation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Trends in microdosing and other exploratory human pharmacokinetic studies for early drug development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Metabolic flux determination in perfused livers by mass balance analysis: effect of fasting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Proteome profiling of mouse embryonic stem cells to define markers for cell differentiation and embryotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Cutaneous metabolic activation of carvoxime, a self-activating, skin-sensitizing prohapten

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

CXCL12 is essential for migration of activated Langerhans cells from epidermis to dermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Comparison of a novel CXCL12/CCL5 dependent migration assay with CXCL8 secretion and CD86 expression for distinguishing sensitizers from non-sensitizers using MUTZ-3 Langerhans cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Syrian hamster embryo (SHE) cell transformation assay with conditioned media (without X-ray irradiated feeder layer) using 2,4-diaminotoluene, 2,6-diaminotoluene and chloral hydrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Assessment of the Embryonic Stem Cell Test and application and use in the pharmaceutical industry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Selection of new chemical entities with decreased potential for adverse drug reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Analysis of published data for top concentration considerations in mammalian cell genotoxicity testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Toxmatch–a new software tool to aid in the development and evaluation of chemically similar groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Human health safety evaluation of cosmetics in the EU: a legally imposed challenge to science

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vitro-in vivo extrapolation of hepatic clearance: biological tools, scaling factors, model assumptions and correct concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Prediction of drug metabolism and interactions on the basis of in vitro investigations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Inhibition and induction of human cytochrome P450 enzymes: current status

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

From known knowns to known unknowns: predicting in vivo drug metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Development of a modified in vitro skin absorption method to study the epidermal/dermal disposition of a contact allergen in human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Application of the CFU-GM assay to predict acute drug-induced neutropenia: an international blind trial to validate a prediction model for the maximum tolerated dose (MTD) of myelosuppressive xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Hematotoxicity testing by cell clonogenic assay in drug development and preclinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Automated analysis of contractility in the embryonic stem cell test, a novel approach to assess embryotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Proteomic analysis of iron overload in human hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Alternative methods for developmental toxicity testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Modified in vitro conditions for cord blood-derived long-term culture-initiating cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Prediction of pharmacokinetics prior to in vivo studies. 1. Mechanism-based prediction of volume of distribution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Development of a novel method for predicting human volume of distribution at steady-state of basic drugs and comparative assessment with existing methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The role of transgenic mouse models in carcinogen identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Assessment of the U937 cell line for the detection of contact allergens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Toxicology databases and the concept of thresholds of toxicological concern as used by the JECFA for the safety evaluation of flavouring agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Computer prediction of possible toxic action from chemical structure: an update on the DEREK system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Detection of immunotoxicity using T-cell based cytokine reporter cell lines ("Cell Chip").

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The derivation of quantitative correlations between skin sensitisation and physio-chemical parameters for alkylating agents, and their application to experimental data for sultones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Experimental reactivity parameters for toxicity modeling: application to the acute aquatic toxicity of SN2 electrophiles to Tetrahymena pyriformis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Embryotoxicant-specific transcriptomic responses in rat postimplantation whole-embryo culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Toxicogenomics applied to in vitro carcinogenicity testing with Balb/c 3T3 cells revealed a gene signature predictive of chemical carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Simulation and prediction of in vivo drug metabolism in human populations from in vitro data

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vitro evaluation of the sensitization potential of weak contact allergens using langerhans-like dendritic cells and autologous T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Cause and consequences of genetic and epigenetic alterations in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The Dermal Sensitisation Threshold- a TTC approach for allergic contact dermatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The relationship between CD86/CD54 expression and THP-1 cell viability in an in vitro skin sensitization test--human cell line activation test (h-CLAT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Comparison of carcinogenic and in vivo genotoxic potency estimates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A toxicogenomic approach to drug-induced phospholipidosis: analysis of its induction mechanism and establishment of a novel in vitro screening system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vitro-Ishikawa cell test for assessing tissue-specific chemical effects on human endometrium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The ReProTect Feasibility Study, a novel comprehensive in vitro approach to detect reproductive toxicants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Effect of human patient plasma ex vivo treatment on gene expression and progenitor cell activation of primary human liver cells in multi-compartment 3D perfusion bioreactors for extra-corporeal liver support.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

TOX 21: new dimensions of toxicity testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

General approach for the calculation of tissue to plasma partition coefficients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A loose-fit coculture of activated keratinocytes and dendritic cell-related cells for prediction of sensitizing potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Comparative aspects of placental exchange functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Structure-activity relationships for reactivity of carbonyl-containing compounds with glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Read-across to rank skin sensitization potential: subcategories for the Michael acceptor domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Development of a screening assay to identify teratogenic and embryotoxic chemicals using the zebrafish embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Identification of the structural requirements for mutagencitiy, by incorporating molecular flexibility and metabolic activation of chemicals. II. General Ames mutagenicity model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The end of the era of generosity? Global health amid economic crisis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Comparison of in vitro hormone activities of selected phthalates using reporter gene assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Sequential Exposure to Cytokines Reflecting Embryogenesis: The Key for in vitro Differentiation of Adult Bone Marrow Stem Cells into Functional Hepatocyte-like Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vitro differentiation of embryonic and adult stem cells into hepatocytes: state of the art.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Reconstructing population exposures from dose biomarkers: inhalation of trichloroethylene (TCE) as a case study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

How to assess the mutagenic potential of cosmetic products without animal tests?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Potential method to determine irritant potency in vitro - Comparison of two reconstructed epidermal culture models with different barrier competency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Discriminating different classes of toxicants by transcript profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Carcinogen-specific gene expression profiles in short-term treated Eker and wild-type rats indicative of pathways involved in renal tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The possible impact of human embryonic stem cells on safety pharmacological and toxicological assessments in drug discovery and drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Hazard assessment of methylmercury toxicity to neuronal induction in embryogenesis using human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Evaluation of changes of cell-surface thiols as a new biomarker for in vitro sensitization test.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Reverse dosimetry: interpreting trihalomethanes biomonitoring data using physiologically based pharmacokinetic modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Use of a physiologically based pharmacokinetic model to identify exposures consistent with human biomonitoring data for chloroform

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Metabolic bioactivation and drug-related adverse effects: current status and future directions from a pharmaceutical research perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A novel system for evaluation of drug mixtures for potential efficacy in treating multidrug resistant cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Identifying chemical carcinogens and assessing potential risk in short-term bioassays using transgenic mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

An abbreviated protocol for multilineage neural differentiation of murine embryonic stem cells and its perturbation by methyl mercury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Automated soft agar assay for the high-throughput screening of anticancer compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Liquid chromatography-mass spectrometry in in vitro drug metabolite screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Additive SMILES-based carcinogenicity models: Probabilistic principles in the search for robust predictions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Prediction of carcinogenic potential by a toxicogenomic approach using rat hepatoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Reconstruction of three-dimensional human skin model composed of dendritic cells, keratinocytes and fibroblasts utilizing a handy scaffold of collagen vitrigel membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A toxicogenomics approach for early assessment of potential non-genotoxic hepatocarcinogenicity of chemicals in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

ReProGlo: a new stem cell-based reporter assay aimed to predict embryotoxic potential of drugs and chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Image analysis and automatic classification of transformed foci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Experimental methods to study human transplacental exposure to genotoxic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Early gene expression changes during embryonic stem cell differentiation into cardiomyocytes and their modulation by monobutyl phthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Transcriptomics-based identification of developmental toxicants through their interference with cardiomyocyte differentiation of embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Comparison of supervised clustering methods to discriminate genotoxic from non-genotoxic carcinogens by gene expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Optimization and prevalidation of the in vitro AR CALUX method to test androgenic and antiandrogenic activity of compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Optimization and prevalidation of the in vitro ERalpha CALUX method to test estrogenic and antiestrogenic activity of compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Using chemical categories to fill data gaps in hazard assessment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Skin sensitization in chemical risk assessment: report of a WHO/IPCS international workshop focusing on dose-response assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vitro effects of dexamethasone on mouse ovarian function and pre-implantation embryo development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Assessment of potency of allergenic activity of low molecular weight compounds based on IL-1alpha and IL-18 production by a murine and human keratinocyte cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Non-animal sensitization testing: state-of-the-art

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Incorporation of 3T3-L1 cells to mimic bioaccumulation in a microscale cell culture analog device for toxicity studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Development of a microscale cell culture analog to probe naphthalene toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Detection of potential (anti)progestagenic endocrine disruptors using a recombinant human progesterone receptor binding and transactivation assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Effector and regulatory mechanisms in allergic contact dermatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The immediate early genes, c-fos, c-jun and AP-1, are early markers of platinum analogue toxicity in human proximal tubular cell primary cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Discrimination of a transformation phenotype in Syrian golden hamster embryo (SHE) cells using ATR-FTIR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Validation of a rapid equilibrium dialysis approach for the measurement of plasma protein binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Characterizing and predicting carcinogenicity and mode of action using conventional and toxicogenomics methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Weight of evidence: a review of concept and methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Predicting human developmental toxicity of pharmaceuticals using human embryonic stem cells and metabolomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

DNA methylation and breast carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

hTERT alone immortalizes epithelial cells of renal proximal tubules without changing their functional characteristics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Use of reporter cell lines for detection of endocrine-disrupter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The potential of embryonic stem cells combined with -omics technologies as model systems for toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The assessment of estrogenic or anti-estrogenic activity of chemicals by the human stably transfected estrogen sensitive MELN cell line: results of test performance and transferability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The hen's egg test for micronucleus induction (HET-MN): novel analyses with a series of well-characterized substances support the further evaluation of the test system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Development of structure-activity relationship rules for predicting carcinogenic potential of chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Discovery of estrogen receptor modulators: a review of virtual screening and SAR efforts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Predictions of hepatic disposition properties using a mechanistically realistic, physiologically based model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Approaches to developing alternative and predictive toxicology based on PBPK/PD and QSAR modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

The methoxychlor metabolite, 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane, inhibits steroidogenesis in rat ovarian granulosa cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

In vivo drug discovery in the zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Molecular markers in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Molecular multiple endpoint embryonic stem cell test--a possible approach to test for the teratogenic potential of compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Monolayer cultivation of osteoprogenitors shortens duration of the embryonic stem cell test while reliably predicting developmental osteotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Statistical Issues in Toxicokinetic Modeling: A Bayesian Perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Physiological Pharmacokinetic Analysis Using Population Modeling and Informative Prior Distributions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

An update on metabolism studies using human hepatocytes in primary culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Transcriptional Activation of CYP2C9, CYP1A1, and CYP1A2 by Hepatocyte Nuclear Factor 4 Requires Coactivators Peroxisomal Proliferator Activated Receptor- Coactivator 1 and Steroid Receptor Coactivator 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

Predictive value of animal models for human cytochrome P450 (CYP)-mediated metabolism: A comparative studyin vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0693-2

10.1007/S00204-011-0693-2

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

31 July 2017

1000516704

0 references

1 reference