Wnt5a is strongly expressed at the leading edge in non-melanoma skin cancer, forming active gradients, while canonical Wnt signalling is repressed (Q34181982)

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English	Wnt5a is strongly expressed at the leading edge in non-melanoma skin cancer, forming active gradients, while canonical Wnt signalling is repressed	scientific article

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scholarly article

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Europe PubMed Central

31 July 2017

Wnt5a is strongly expressed at the leading edge in non-melanoma skin cancer, forming active gradients, while canonical Wnt signalling is repressed (English)

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Europe PubMed Central

31 July 2017

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Andrey A Panteleyev

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Andrey Panteleyev

4

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author name string

Celine Pourreyron

1

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Europe PubMed Central

31 July 2017

Louise Reilly

2

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Europe PubMed Central

31 July 2017

Charlotte Proby

3

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Europe PubMed Central

31 July 2017

Colin Fleming

5

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Europe PubMed Central

31 July 2017

Kathleen McLean

6

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Europe PubMed Central

31 July 2017

Andrew P South

7

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Europe PubMed Central

31 July 2017

John Foerster

8

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Europe PubMed Central

31 July 2017

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22 February 2012

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Europe PubMed Central

31 July 2017

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Europe PubMed Central

31 July 2017

7

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Europe PubMed Central

31 July 2017

2

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Europe PubMed Central

31 July 2017

e31827

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Europe PubMed Central

31 July 2017

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Creative Commons Attribution 4.0 International

22 February 2012

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April 2022 Public Data File from Crossref

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Activation of the Wnt/β-catenin signaling pathway by mechanical ventilation is associated with ventilator-induced pulmonary fibrosis in healthy lungs

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WNT5A signaling contributes to Aβ-induced neuroinflammation and neurotoxicity

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Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma

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Critical role of Wnt5a-Ror2 signaling in motility and invasiveness of carcinoma cells following Snail-mediated epithelial-mesenchymal transition

1 reference

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Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2

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28 July 2018

Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors.

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Microarray analysis of cutaneous squamous cell carcinomas reveals enhanced expression of epidermal differentiation complex genes

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Wnt5a induces endothelial inflammation via beta-catenin-independent signaling

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Cell/tissue-tropic functions of Wnt5a signaling in normal and cancer cells

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Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells

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Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells

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The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

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Towards an integrated view of Wnt signaling in development

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The opposing roles of Wnt-5a in cancer

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Laminin gamma2 mediates Wnt5a-induced invasion of gastric cancer cells

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Autonomous regulation of osteosarcoma cell invasiveness by Wnt5a/Ror2 signaling

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28 July 2018

Wnt5a exhibits layer-specific expression in adult skin, is upregulated in psoriasis, and synergizes with type 1 interferon

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Wnt-5a-CKI{alpha} signaling promotes {beta}-catenin/E-cadherin complex formation and intercellular adhesion in human breast epithelial cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285195

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Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction

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Promoter methylation of SFRPs gene family in cervical cancer

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Comprehensive Wnt-related gene expression during cochlear duct development in chicken.

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Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer

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The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.

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WNT5A--target of CUTL1 and potent modulator of tumor cell migration and invasion in pancreatic cancer

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Differences in expression of specific biomarkers distinguish human beard from scalp dermal papilla cells

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The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation

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Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285195

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Differential inhibition of Wnt-3a by Sfrp-1, Sfrp-2, and Sfrp-3.

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FrzA, a secreted frizzled related protein, induced angiogenic response

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Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

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A model for signaling specificity of Wnt/Frizzled combinations through co-receptor recruitment.

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21 January 2018

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Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors

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Activation of PPARbeta/delta causes a psoriasis-like skin disease in vivo

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Evidence for altered Wnt signaling in psoriatic skin.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031827

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Expression of Frizzleds and secreted frizzled-related proteins (Sfrps) during mammalian lens development.

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The hypermethylation and protein expression of p16 INK4A and DNA repair gene O6-methylguanine-DNA methyltransferase in various uterine cervical lesions.

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21 January 2018

WNT pathway in oral cancer: epigenetic inactivation of WNT-inhibitors.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285195

28 October 2018

A secreted frizzled related protein, FrzA, selectively associates with Wnt-1 protein and regulates wnt-1 signaling.

1 reference

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28 October 2018

Functional and biochemical interactions of Wnts with FrzA, a secreted Wnt antagonist.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285195

28 October 2018

Increased nuclear beta-catenin in suprabasal involved psoriatic epidermis

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12 December 2020

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PPARdelta enhances keratinocyte proliferation in psoriasis and induces heparin-binding EGF-like growth factor

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https://pubmed.ncbi.nlm.nih.gov/22384081

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Secreted frizzled-related protein-1 enhances mesenchymal stem cell function in angiogenesis and contributes to neovessel maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22384081

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Transcriptional profiling shows altered expression of wnt pathway- and lipid metabolism-related genes as well as melanogenesis-related genes in melasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22384081

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based on heuristic

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10.1371/JOURNAL.PONE.0031827

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Europe PubMed Central

31 July 2017

2012PLoSO...731827P

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24 November 2022

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Europe PubMed Central

31 July 2017

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Europe PubMed Central

31 July 2017

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