Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1. (Q34185295)

31 July 2017

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title

Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1. (English)

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31 July 2017

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5

Bert W O'Malley

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31 July 2017

Lan Liao

1

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31 July 2017

Shao-Qing Kuang

2

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31 July 2017

Yuhui Yuan

3

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31 July 2017

Sonia M Gonzalez

4

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31 July 2017

Jianming Xu

6

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31 July 2017

language of work or name

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1 December 2002

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The Journal of Steroid Biochemistry and Molecular Biology

31 July 2017

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31 July 2017

83

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31 July 2017

1-5

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31 July 2017

3-14

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Molecular mechanisms of action of steroid/thyroid receptor superfamily members

31 July 2017

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The nuclear receptor superfamily: the second decade

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A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex

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A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA

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Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

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The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements

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7 January 2021

Combinatorial control of gene expression by nuclear receptors and coregulators

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7 January 2021

Interactions between the retinoid X receptor and a conserved region of the TATA-binding protein mediate hormone-dependent transactivation

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Transcriptional activators differ in their responses to overexpression of TATA-box-binding protein

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7 January 2021

Identification of a transactivation function in the progesterone receptor that interacts with the TAFII110 subunit of the TFIID complex

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Interaction of the human androgen receptor transactivation function with the general transcription factor TFIIF

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Stimulation of RAR alpha activation function AF-1 through binding to the general transcription factor TFIIH and phosphorylation by CDK7

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7 January 2021

Transcription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription.

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Negative effect of the transcriptional activator GAL4

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7 January 2021

Steroid hormone receptors compete for factors that mediate their enhancer function

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7 January 2021

The human estrogen receptor has two independent nonacidic transcriptional activation functions

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7 January 2021

Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors

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Interaction of proteins with transcriptionally active estrogen receptors

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7 January 2021

Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription

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7 January 2021

Sequence and characterization of a coactivator for the steroid hormone receptor superfamily

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GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors

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7 January 2021

A transcriptional coactivator, steroid receptor coactivator-3, selectively augments steroid receptor transcriptional activity

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7 January 2021

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

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7 January 2021

RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2

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7 January 2021

Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300

1 reference

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7 January 2021

TRAM-1, A novel 160-kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator-1

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7 January 2021

Identification of cryptic sites of DNA sequence amplification in human breast cancer by chromosome microdissection

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7 January 2021

AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer

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7 January 2021

PAS is a dimerization domain common to Drosophila period and several transcription factors.

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Distinct steady-state nuclear receptor coregulator complexes exist in vivo

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7 January 2021

Functional interaction between the p160 coactivator proteins and the transcriptional enhancer factor family of transcription factors

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7 January 2021

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

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7 January 2021

The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways

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7 January 2021

The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors.

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7 January 2021

The receptor-associated coactivator 3 activates transcription through CREB-binding protein recruitment and autoregulation

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7 January 2021

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

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Molecular basis of agonism and antagonism in the oestrogen receptor

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p300 requires its histone acetyltransferase activity and SRC-1 interaction domain to facilitate thyroid hormone receptor activation in chromatin

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7 January 2021

Steroid receptor coactivator-1 is a histone acetyltransferase

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7 January 2021

Regulation of transcription by a protein methyltransferase

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7 January 2021

Synergistic enhancement of nuclear receptor function by p160 coactivators and two coactivators with protein methyltransferase activities

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7 January 2021

A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo

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7 January 2021

Cloning and characterization of RAP250, a novel nuclear receptor coactivator

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Isolation and characterization of peroxisome proliferator-activated receptor (PPAR) interacting protein (PRIP) as a coactivator for PPAR

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7 January 2021

Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator

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7 January 2021

A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein

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7 January 2021

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex

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7 January 2021

A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system

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7 January 2021

Steroid receptor coactivator-1 (SRC-1) enhances ligand-dependent and receptor-dependent cell-free transcription of chromatin

1 reference

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7 January 2021

Sequential recruitment of steroid receptor coactivator-1 (SRC-1) and p300 enhances progesterone receptor-dependent initiation and reinitiation of transcription from chromatin

1 reference

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7 January 2021

Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

1 reference

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7 January 2021

Regulation of somatic growth by the p160 coactivator p/CIP

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7 January 2021

AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor

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7 January 2021

Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase

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7 January 2021

Structure and chromosomal locations of mouse steroid receptor coactivator gene family

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7 January 2021

An isoform of the coactivator AIB1 that increases hormone and growth factor sensitivity is overexpressed in breast cancer.

1 reference

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7 January 2021

Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene

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7 January 2021

The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development

1 reference

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7 January 2021

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

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7 January 2021

The protective effects of estrogen on the cardiovascular system

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7 January 2021

The vascular protective effects of estrogen.

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Estrogen receptor alpha mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen

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Estrogen-induced vasoprotection is estrogen receptor dependent: evidence from the balloon-injured rat carotid artery model.

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7 January 2021

Human vascular smooth muscle cells contain functional estrogen receptor

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Identification of authentic estrogen receptor in cultured endothelial cells. A potential mechanism for steroid hormone regulation of endothelial function

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Steroid receptor coactivator-3 is required for inhibition of neointima formation by estrogen

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7 January 2021

Remodeling with neointima formation in the mouse carotid artery after cessation of blood flow

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7 January 2021

Regulation of invasive cell behavior by taiman, a Drosophila protein related to AIB1, a steroid receptor coactivator amplified in breast cancer

1 reference

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7 January 2021

Ribozyme targeting demonstrates that the nuclear receptor coactivator AIB1 is a rate-limiting factor for estrogen-dependent growth of human MCF-7 breast cancer cells.

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7 January 2021

Expression of the nuclear coactivator AIB1 in normal and malignant breast tissue.

1 reference

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7 January 2021

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

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7 January 2021

Expression of RAC 3, a steroid hormone receptor co-activator in prostate cancer

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7 January 2021

Expression of androgen receptor coregulatory proteins in prostate cancer and stromal-cell culture models

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7 January 2021

10.1016/S0960-0760(02)00254-6

Identifiers

DOI

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31 July 2017

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