Marked reduction of AKT1 expression and deregulation of AKT1-associated pathways in peripheral blood mononuclear cells of schizophrenia patients (Q34185951)

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English	Marked reduction of AKT1 expression and deregulation of AKT1-associated pathways in peripheral blood mononuclear cells of schizophrenia patients	scientific article

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scholarly article

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Europe PubMed Central

31 July 2017

Marked reduction of AKT1 expression and deregulation of AKT1-associated pathways in peripheral blood mononuclear cells of schizophrenia patients (English)

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Europe PubMed Central

31 July 2017

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6

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Lieuwe de Haan

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Europe PubMed Central

31 July 2017

author name string

Nico J M van Beveren

1

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Europe PubMed Central

31 July 2017

Gabrielle H S Buitendijk

2

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Europe PubMed Central

31 July 2017

Sigrid Swagemakers

3

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Europe PubMed Central

31 July 2017

Lianne C Krab

4

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Europe PubMed Central

31 July 2017

Christian Röder

5

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Europe PubMed Central

31 July 2017

Peter van der Spek

7

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Europe PubMed Central

31 July 2017

Ype Elgersma

8

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Europe PubMed Central

31 July 2017

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publication date

29 February 2012

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Europe PubMed Central

31 July 2017

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Europe PubMed Central

31 July 2017

7

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Europe PubMed Central

31 July 2017

2

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Europe PubMed Central

31 July 2017

e32618

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Europe PubMed Central

31 July 2017

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Creative Commons Attribution 4.0 International

29 February 2012

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April 2022 Public Data File from Crossref

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Akt1 and Akt2: differentiating the aktion

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Altered levels of circulating insulin and other neuroendocrine hormones associated with the onset of schizophrenia.

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5 July 2018

The environment and schizophrenia

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5 July 2018

Rethinking schizophrenia

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5 July 2018

Roles of the Akt/GSK-3 and Wnt signaling pathways in schizophrenia and antipsychotic drug action

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5 July 2018

Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk

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Lack of association between AKT1 variances versus clinical manifestations and social function in patients with schizophrenia

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Schizophrenia susceptibility genes directly implicated in the life cycles of pathogens: cytomegalovirus, influenza, herpes simplex, rubella, and Toxoplasma gondii.

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Fibroblast and lymphoblast gene expression profiles in schizophrenia: are non-neural cells informative?

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A signaling pathway AKTing up in schizophrenia

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No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics

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AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families

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5 July 2018

Molecular evidence for increased expression of genes related to immune and chaperone function in the prefrontal cortex in schizophrenia.

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5 July 2018

Neurotrophins and schizophrenia.

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5 July 2018

The Akt-GSK-3 signaling cascade in the actions of dopamine

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5 July 2018

Regulation of Akt signaling by D2 and D3 dopamine receptors in vivo

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5 July 2018

Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning

1 reference

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5 July 2018

Schizophrenia as an inflammation-mediated dysbalance of glutamatergic neurotransmission

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Schizophrenia susceptibility genes converge on interlinked pathways related to glutamatergic transmission and long-term potentiation, oxidative stress and oligodendrocyte viability.

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Gene expression profiling in schizophrenia and related mental disorders.

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5 July 2018

Schizophrenia-associated neural growth factors in peripheral blood. A review

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5 July 2018

Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia

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5 July 2018

An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior

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5 July 2018

Recent advances in the protein kinase B signaling pathway

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5 July 2018

Theories of schizophrenia: a genetic-inflammatory-vascular synthesis

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5 July 2018

Immune dysregulation and self-reactivity in schizophrenia: do some cases of schizophrenia have an autoimmune basis?

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5 July 2018

Low GSK-3beta in schizophrenia as a consequence of neurodevelopmental insult

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5 July 2018

Advances in protein kinase B signalling: AKTion on multiple fronts

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5 July 2018

Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia

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5 July 2018

Microarray screening of lymphocyte gene expression differences in a multiplex schizophrenia pedigree

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5 July 2018

Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia

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5 July 2018

PKB binding proteins. Getting in on the Akt.

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5 July 2018

GSK-3 parameters in lymphocytes of schizophrenic patients

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290567

5 July 2018

Review of immunological and immunopathological findings in schizophrenia

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5 July 2018

Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex

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Schizophrenia as a disorder of developmentally reduced synaptic connectivity

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The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

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The role of gender differences in the reduction of etiologic heterogeneity in schizophrenia

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Assessing the validity of blood-based gene expression profiles for the classification of schizophrenia and bipolar disorder: a preliminary report

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Evaluating the comparability of gene expression in blood and brain.

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Differences in lymphocyte electron transport gene expression levels between subjects with bipolar disorder and normal controls in response to glucose deprivation stress.

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Association analysis of AKT1 and schizophrenia in a UK case control sample

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Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction.

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Hepatic insulin resistance in antipsychotic naive schizophrenic patients: stable isotope studies of glucose metabolism

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Increased levels of circulating insulin-related peptides in first-onset, antipsychotic naïve schizophrenia patients

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Association of AKT1 gene polymorphisms with risk of schizophrenia and with response to antipsychotics in the Chinese population

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The role of DTNBP1, NRG1, and AKT1 in the genetics of schizophrenia in Finland

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Gene expression analysis of peripheral blood leukocytes from discordant sib-pairs with schizophrenia and bipolar disorder reveals points of convergence between genetic and functional genomic approaches

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Failure to confirm association between AKT1 haplotype and schizophrenia in a Japanese case-control population

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Further evidence for association of variants in the AKT1 gene with schizophrenia in a sample of European sib-pair families

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https://pubmed.ncbi.nlm.nih.gov/22393424

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based on heuristic

inferred from PubMed ID database lookup

Gene expression microarray studies in polygenic psychiatric disorders: applications and data analysis

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https://pubmed.ncbi.nlm.nih.gov/22393424

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based on heuristic

inferred from PubMed ID database lookup

Association of AKT1 haplotype with the risk of schizophrenia in Iranian population

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based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0032618

1 reference

Europe PubMed Central

31 July 2017

2012PLoSO...732618V

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24 November 2022

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mapped directly with Wikidata item

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Europe PubMed Central

31 July 2017

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Europe PubMed Central

31 July 2017

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