Effects of the PPARα Agonist and Widely Used Antihyperlipidemic Drug Gemfibrozil on Hepatic Toxicity and Lipid Metabolism (Q34189111)

31 July 2017

title

Effects of the PPARα Agonist and Widely Used Antihyperlipidemic Drug Gemfibrozil on Hepatic Toxicity and Lipid Metabolism (English)

1 reference

31 July 2017

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Michael L Cunningham

1

1 reference

31 July 2017

Bradley J Collins

2

1 reference

31 July 2017

Milton R Hejtmancik

3

1 reference

31 July 2017

Ronald A Herbert

4

1 reference

31 July 2017

Gregory S Travlos

5

1 reference

31 July 2017

Molly K Vallant

6

1 reference

31 July 2017

Matthew D Stout

7

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31 July 2017

publication date

4 October 2010

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31 July 2017

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31 July 2017

volume

2010

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Creative Commons Attribution 3.0 Unported

31 July 2017

copyright license

start time

1 January 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats.

5 July 2018

1 reference

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5 July 2018

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5 July 2018

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Coupled-enzyme determination of catalase activity in erythrocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952818

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952818

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952818

Regulation of perfluorooctanoic acid–induced peroxisomal enzyme activities and hepatocellular growth by adrenal hormones

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952818

A non-parametric equivalent of Williams' test for contrasting increasing dose levels of a treatment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952818

Tumors in male rats fed ethyl chlorophenoxyisobutyrate, a hypolipidemic drug

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952818

Tumorigenicity of the hypolipidaemic peroxisome proliferator ethyl-α-p-chlorophenoxyisobutyrate (clofibrate) in rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952818

Statistical issues in interpretation of chronic bioassay tests for carcinogenicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952818

Mitogenic and carcinogenic effects of a hypolipidemic peroxisome proliferator, [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14, 643), in rat and mouse liver

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952818

Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor alpha

5 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F681963

Peroxisome proliferators do not activate the transcription factors AP-1, early growth response-1, or heat shock factors 1 and 2 in rats or hamsters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F681963

Effects of peroxisome proliferators on antioxidant enzymes and antioxidant vitamins in rats and hamsters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F681963

Hepatic expression of polymerase beta, Ref-1, PCNA, and Bax in WY 14,643-exposed rats and hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F681963

Effect of peroxisome proliferators on the methylation and protein level of the c-myc protooncogene in B6C3F1 mice liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F681963

Species differences in the testicular toxicity of phthalate esters

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F681963

Determination of serum catalase activity on a centrifugal analyzer by an NADP/NADPH coupled enzyme reaction system

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F681963

Choosing hamsters but not rats as a model for studying plasma cholesterol-lowering activity of functional foods.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F681963

A Multiple Comparison Procedure for Comparing Several Treatments with a Control

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F681963

Toxicity studies of WY-14,643 (CAS No. 50892-23-4) administered in feed to male Sprague-Dawley rats, B6C3F1 mice, and Syrian hamsters.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952818

Carcinogen bioassay and mutagenicity studies with the hypolipidemic agent gemfibrozil.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952818

Relationship between morphological changes and lipid-lowering action of p-chlorphenoxyisobutyric acid (CPIB) on hepatic mitochondria and peroxisomes in man

28 October 2018

1 reference

12 December 2020

Assay of peroxisomal beta-oxidation of fatty acids

1 reference

12 December 2020

Genotoxicity of acyl glucuronide metabolites formed from clofibric acid and gemfibrozil: a novel role for phase-II-mediated bioactivation in the hepatocarcinogenicity of the parent aglycones?

1 reference

12 December 2020

Beneficial effects of fibrates on apolipoprotein A-I metabolism occur independently of any peroxisome proliferative response

1 reference

12 December 2020

Subchronic toxicity of Di(2-ethylhexyl)phthalate in common marmosets: lack of hepatic peroxisome proliferation, testicular atrophy, or pancreatic acinar cell hyperplasia

1 reference

12 December 2020

The comparison of several dose levels with a zero dose control

1 reference

12 December 2020

Differential effects of altered hormonal state on the induction of ACYL-CoA hydrolases and peroxisomal β-oxidation by clofibric acid

1 reference

12 December 2020

Effects of di-isononyl phthalate, di-2-ethylhexyl phthalate, and clofibrate in cynomolgus monkeys

1 reference

12 December 2020

A note on Shirley's nonparametric test for comparing several dose levels with a zero-dose control

1 reference

12 December 2020

Peroxisome proliferator-activated receptor alpha: role in rodent liver cancer and species differences

1 reference

12 December 2020

Peroxisome proliferation in cultured rat hepatocytes produced by clofibrate and phthalate ester metabolites

1 reference

12 December 2020

Induction of peroxisomal enzyme activities by di-(2-ethylhexyl) phthalate in thyroidectomized rats with parathyroid replants

1 reference

12 December 2020

Di(2-ethylhexyl)phthalate induces hepatic tumorigenesis through a peroxisome proliferator-activated receptor alpha-independent pathway

1 reference

12 December 2020

A Test for Differences between Treatment Means When Several Dose Levels are Compared with a Zero Dose Control

1 reference

12 December 2020

Identifiers

DOI

10.1155/2010/681963

1 reference

31 July 2017

1 reference

31 July 2017

1 reference