HIV controllers with HLA-DRB113 and HLA-DQB106 alleles have strong, polyfunctional mucosal CD4+ T-cell responses (Q34190681)

31 July 2017

title

HIV controllers with HLA-DRB1*13 and HLA-DQB1*06 alleles have strong, polyfunctional mucosal CD4+ T-cell responses (English)

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31 July 2017

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9

Steven G Deeks

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31 July 2017

April L Ferre

1

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31 July 2017

Peter W Hunt

2

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31 July 2017

Delandy H McConnell

3

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31 July 2017

Megan M Morris

4

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31 July 2017

Juan C Garcia

5

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31 July 2017

Richard B Pollard

6

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31 July 2017

Hal F Yee

7

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31 July 2017

Jeffrey N Martin

8

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31 July 2017

Barbara L Shacklett

10

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31 July 2017

language of work or name

English

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publication date

18 August 2010

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31 July 2017

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31 July 2017

volume

84

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31 July 2017

issue

21

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31 July 2017

page(s)

11020-11029

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HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity

31 July 2017

cites work

1 reference

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HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognition

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Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control

28 July 2018

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Magnitude and complexity of rectal mucosa HIV-1-specific CD8+ T-cell responses during chronic infection reflect clinical status

28 July 2018

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Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy

28 July 2018

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Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid

28 July 2018

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28 July 2018

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28 July 2018

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The major histocompatibility complex class II alleles Mamu-DRB1*1003 and -DRB1*0306 are enriched in a cohort of simian immunodeficiency virus-infected rhesus macaque elite controllers

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

28 July 2018

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Phenotypic, functional, and kinetic parameters associated with apparent T-cell control of human immunodeficiency virus replication in individuals with and without antiretroviral treatment

28 July 2018

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Parallel human immunodeficiency virus type 1-specific CD8+ T-lymphocyte responses in blood and mucosa during chronic infection

28 July 2018

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28 July 2018

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28 July 2018

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Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides

28 July 2018

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Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities

28 July 2018

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The influence of HLA genotype on AIDS

28 July 2018

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Expansion of pre-existing, lymph node-localized CD8+ T cells during supervised treatment interruptions in chronic HIV-1 infection

28 July 2018

1 reference

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Role for HLA class II molecules in HIV-1 suppression and cellular immunity following antiretroviral treatment

28 July 2018

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The role of CD4(+) T helper cells in the cytotoxic T lymphocyte response to HIV-1.

28 July 2018

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HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors

28 July 2018

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28 July 2018

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Viral immune evasion due to persistence of activated T cells without effector function

28 July 2018

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The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses

28 July 2018

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Several common HLA-DR types share largely overlapping peptide binding repertoires

28 July 2018

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Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia

28 July 2018

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28 July 2018

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Phylogenetic analysis of gag genes from 70 international HIV-1 isolates provides evidence for multiple genotypes

28 July 2018

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Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

28 July 2018

1 reference

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CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953185

Association between an MHC class II allele and clearance of hepatitis B virus in the Gambia

28 July 2018

1 reference

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Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953185

Common west African HLA antigens are associated with protection from severe malaria

28 July 2018

1 reference

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Major core proteins, p24s, of human, simian, and feline immunodeficiency viruses are partly expressed on the surface of the virus-infected cells

28 July 2018

1 reference

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Immunodominant HIV-Specific CD8+T-Cell Responses Are Common to Blood and Gastrointestinal Mucosa, and Gag-Specific Responses Dominate in Rectal Mucosa of HIV Controllers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953185

Quantifying HIV-1-specific CD8 (+) T-cell responses using ELISPOT and cytokine flow cytometry.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953185

Isolating mucosal lymphocytes from biopsy tissue for cellular immunology assays

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953185

Preserved central memory and activated effector memory CD4+ T-cell subsets in human immunodeficiency virus controllers: an ANRS EP36 study

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953185

Functional heterogeneity of memory CD4 T cell responses in different conditions of antigen exposure and persistence.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953185

Optimization of methods to assess human mucosal T-cell responses to HIV infection.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953185

Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: changes after antiretroviral therapy

28 October 2018

1 reference

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Loss of CD4+ T cell proliferative ability but not loss of human immunodeficiency virus type 1 specificity equates with progression to disease

28 October 2018

1 reference

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Consistent associations of HLA class I and II and transporter gene products with progression of human immunodeficiency virus type 1 infection in homosexual men.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953185

A chain section containing epitopes for cytotoxic T, B and helper T cells within a highly conserved region found in the human immunodeficiency virus type 1 Gag protein

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953185

HLA DR-DQ associations with cervical carcinoma show papillomavirus-type specificity

28 October 2018

1 reference

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Presence of HIV-1 Gag-specific IFN-gamma+IL-2+ and CD28+IL-2+ CD4 T cell responses is associated with nonprogression in HIV-1 infection

28 October 2018

1 reference

12 December 2020

The mechanism of anti-CD3 monoclonal antibodies. Mediation of cytolysis by inter-T cell bridging

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12 December 2020

HIV-1 gag-specific cytotoxic T lymphocytes recognize multiple highly conserved epitopes. Fine specificity of the gag-specific response defined by using unstimulated peripheral blood mononuclear cells and cloned effector cells

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Influence of HLA Alleles on the Rate of Progression of Vertically Transmitted HIV Infection in Children: Association of Several HLA-DR13 Alleles with Long-Term Survivorship and the Potential Association of HLA-A2301 with Rapid Progression to AIDS

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Identifiers

DOI

10.1128/JVI.00980-10

1 reference

31 July 2017

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31 July 2017

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