DHT Selectively Reverses Smad3-Mediated/TGF-β-Induced Responses through Transcriptional Down-Regulation of Smad3 in Prostate Epithelial Cells (Q34197256)

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scientific article published on August 25, 2010

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English	DHT Selectively Reverses Smad3-Mediated/TGF-β-Induced Responses through Transcriptional Down-Regulation of Smad3 in Prostate Epithelial Cells	scientific article published on August 25, 2010

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

DHT selectively reverses Smad3-mediated/TGF-beta-induced responses through transcriptional down-regulation of Smad3 in prostate epithelial cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

DHT Selectively Reverses Smad3-Mediated/TGF-β-Induced Responses through Transcriptional Down-Regulation of Smad3 in Prostate Epithelial Cells (English)

1 reference

10.1210/ME.2010-0165

https://api.crossref.org/works/10.1210/ME.2010-0165

23 June 2024

author name string

Kyung Song

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Hui Wang

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Bingcheng Wang

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

David Danielpour

6

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Tracy L. Krebs

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739403

23 June 2024

Thomas J. Kelley

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739403

23 June 2024

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20739403

23 June 2024

publication date

25 August 2010

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Europe PubMed Central

PubMed publication ID

31 July 2017

full work available at URL

https://academic.oup.com/mend/article-pdf/24/10/2019/8943130/mend2019.pdf

Portable Document Format

online access status

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739403

23 June 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20739403/?tool=EBI

online access status

content deliverer

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739403

23 June 2024

http://intl-mend.endojournals.org/cgi/content/abstract/24/10/2019

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739403

23 June 2024

https://europepmc.org/articles/PMC2954637

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739403

23 June 2024

https://doi.org/10.1210/me.2010-0165

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739403

23 June 2024

http://academic.oup.com/mend/article-pdf/24/10/2019/8943130/mend2019.pdf

Portable Document Format

1 reference

10.1210/ME.2010-0165

https://api.crossref.org/works/10.1210/ME.2010-0165

23 June 2024

Molecular Endocrinology

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

24

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

2019-2029

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Critical role of Smad2 in tumor suppression and transforming growth factor-beta-induced apoptosis of prostate epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Androgen modulation of coregulator expression in prostate cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Androgenic control of transforming growth factor-beta signaling in prostate epithelial cells through transcriptional suppression of transforming growth factor-beta receptor II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Targeting the androgen receptor pathway in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Transcriptional regulation of the TGF-beta1 promoter by androgen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Stromal transforming growth factor-beta signaling mediates prostatic response to androgen ablation by paracrine Wnt activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Rb/E2F4 and Smad2/3 link survivin to TGF-beta-induced apoptosis and tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

TGF-beta signaling and androgen receptor status determine apoptotic cross-talk in human prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Negative regulation of TGF-beta receptor/Smad signal transduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Androgen receptor corepressors and prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Androgen receptor as a licensing factor for DNA replication in androgen-sensitive prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Novel permissive role of epidermal growth factor in transforming growth factor beta (TGF-beta) signaling and growth suppression. Mediation by stabilization of TGF-beta receptor type II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Novel roles of Akt and mTOR in suppressing TGF-beta/ALK5-mediated Smad3 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Cross-talk between IGF-I and TGF-beta signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Functions and regulation of transforming growth factor-beta (TGF-beta) in the prostate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Androgen receptor in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Isoprenoid-mediated control of SMAD3 expression in a cultured model of cystic fibrosis epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

The two faces of transforming growth factor beta in carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Differential modulation of androgen receptor-mediated transactivation by Smad3 and tumor suppressor Smad4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Androgen receptor (AR) coregulators: an overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Identification of two Sp1 phosphorylation sites for p42/p44 mitogen-activated protein kinases: their implication in vascular endothelial growth factor gene transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Androgen suppression of GnRH-stimulated rat LHbeta gene transcription occurs through Sp1 sites in the distal GnRH-responsive promoter region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

VCaP, a cell-based model system of human prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

SMAD3 represses androgen receptor-mediated transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

From transforming growth factor-beta signaling to androgen action: identification of Smad3 as an androgen receptor coregulator in prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

LNCaP progression model of human prostate cancer: androgen-independence and osseous metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Controlling TGF-beta signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

The Smad pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Increased smad expression and activation are associated with apoptosis in normal and malignant prostate after castration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954637

5 July 2018

Transdifferentiation of NRP-152 rat prostatic basal epithelial cells toward a luminal phenotype: regulation by glucocorticoid, insulin-like growth factor-I and transforming growth factor-beta

1 reference

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The role of transforming growth factor-beta1, -beta2, and -beta3 in androgen-responsive growth of NRP-152 rat prostatic epithelial cells

1 reference

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Regulation of apoptosis induced by transforming growth factor-beta1 in nontumorigenic rat prostatic epithelial cell lines

1 reference

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Development and characterization of nontumorigenic and tumorigenic epithelial cell lines from rat dorsal-lateral prostate

1 reference

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The proliferative function of basal cells in the normal and hyperplastic human prostate

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Multidirectional differentiation in the normal, hyperplastic, and neoplastic human prostate: simultaneous demonstration of cell-specific epithelial markers

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Response of glandular versus basal rat ventral prostatic epithelial cells to androgen withdrawal and replacement

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Androgen receptor localization in different cell types of the adult rat prostate

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Androgen receptor and TGFbeta1/Smad signaling are mutually inhibitory in prostate cancer

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based on heuristic

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Characterization of the nontransformed and transformed androgen receptor and heat shock protein 90 with high-performance hydrophobic-interaction chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/20739403

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Expression of transforming growth factor-beta in the rat ventral prostate during castration-induced programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/20739403

12 December 2020

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Changes in gene expression of growth factors and their receptors during castration-induced involution and androgen-induced regrowth of rat prostates

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https://pubmed.ncbi.nlm.nih.gov/20739403

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https://pubmed.ncbi.nlm.nih.gov/20739403

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Expression and localization of transforming growth factor-beta receptors type I and type II in the rat ventral prostate during regression

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https://pubmed.ncbi.nlm.nih.gov/20739403

12 December 2020

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Identifiers

10.1210/ME.2010-0165

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

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