The growth arrest-specific gene product Gas6 promotes the survival of human oligodendrocytes via a phosphatidylinositol 3-kinase-dependent pathway. (Q34199507)

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English	The growth arrest-specific gene product Gas6 promotes the survival of human oligodendrocytes via a phosphatidylinositol 3-kinase-dependent pathway.	scientific article

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3 November 2019

The growth arrest-specific gene product Gas6 promotes the survival of human oligodendrocytes via a phosphatidylinositol 3-kinase-dependent pathway (English)

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3 November 2019

oligodendrocyte

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3

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6

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Sai Latha Shankar

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3 November 2019

Kathleen O'Guin

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F Arthur McMorris

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3 November 2019

Trevor N Stitt

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Brian Varnum

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3 November 2019

Bridget Shafit-Zagardo

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1 May 2003

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3 November 2019

Journal of Neuroscience

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10

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3 November 2019

4208-4218

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3 November 2019

Expression of receptor tyrosine kinase Axl and its ligand Gas6 in rheumatoid arthritis: evidence for a novel endothelial cell survival pathway

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https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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A novel microtubule-associated protein-2 expressed in oligodendrocytes in multiple sclerosis lesions

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https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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Novel microtubule-associated protein-2 isoform is expressed early in human oligodendrocyte maturation

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https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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Tracing human oligodendroglial development in vitro

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https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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Nerve Growth Factor Protects Oligodendrocytes from Tumor Necrosis Factor-α-induced Injury through Akt-mediated Signaling Mechanisms

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https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

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Syk is required for the activation of Akt survival pathway in B cells exposed to oxidative stress

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https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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Expression of the receptor protein-tyrosine kinases Tyro-3, Axl, and mer in the developing rat central nervous system

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https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

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Hematopoietic progenitor cells grow on 3T3 fibroblast monolayers that overexpress growth arrest-specific gene-6 (GAS6).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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Phagocytosis and clearance of apoptotic cells is mediated by MER.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gas 6 promotes Axl-mediated survival in pulmonary endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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Identification of Gas6, a putative ligand for Sky and Axl receptor tyrosine kinases, as a novel neurotrophic factor for hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor mediates signal transduction through trk homodimer receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

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The murine ufo receptor: molecular cloning, chromosomal localization and in situ expression analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

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The oligodendrocyte and its many cellular processes

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https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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A novel oncogene, v-ryk, encoding a truncated receptor tyrosine kinase is transduced into the RPL30 virus without loss of viral sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

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Cell death and control of cell survival in the oligodendrocyte lineage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel putative tyrosine kinase receptor with oncogenic potential

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12 December 2020

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A putative receptor tyrosine kinase with unique structural topology

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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Neurobiology of human oligodendrocytes in culture.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

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Direct microculture enzyme-linked immunosorbent assay for studying neural cells: oligodendrocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

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Cyclic AMP regulates the rate of differentiation of oligodendrocytes without changing the lineage commitment of their progenitors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

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Multiple and novel specificities of monoclonal antibodies O1, O4, and R-mAb used in the analysis of oligodendrocyte development

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

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Oligodendrocyte progenitors isolated directly from developing telencephalon at a specific phenotypic stage: myelinogenic potential in a defined environment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium

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https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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Correlation of fetal age and measurements between 10 and 26 weeks of gestation

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https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: an immunocytological study in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proto-oncogene of v-eyk (v-ryk) is a novel receptor-type protein tyrosine kinase with extracellular Ig/GN-III domains.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical detection of myelin basic protein is a sensitive marker of myelination in second trimester human fetal spinal cord.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reevaluation of the roles of protein S and Gas6 as ligands for the receptor tyrosine kinase Rse/Tyro 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human microtubule-associated protein-2c localizes to dendrites and axons in fetal spinal motor neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure, expression, and activity of Tyro 3, a neural adhesion-related receptor tyrosine kinase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and mRNA expression analysis of a novel human protooncogene, c-mer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

brt, a mouse gene encoding a novel receptor-type protein-tyrosine kinase, is preferentially expressed in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of the cDNA for a novel receptor tyrosine kinase, Sky, predominantly expressed in brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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Molecular cloning of a novel receptor tyrosine kinase, tif, highly expressed in human ovary and testis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

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Expression of oligodendrocyte-associated genes in cell lines derived from human gliomas and neuroblastomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

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Mitogenic signals and transforming potential of Nyk, a newly identified neural cell adhesion molecule-related receptor tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of Gas6 as a growth factor for human Schwann cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of Gas6, a member of the superfamily of G domain-containing proteins, as a ligand for Rse and Axl

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gas6, the ligand of Axl tyrosine kinase receptor, has mitogenic and survival activities for serum starved NIH3T3 fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal and spatial expression of major myelin proteins in the human fetal spinal cord during the second trimester

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation and death of premyelinating oligodendrocytes in developing rodent brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of phosphatidylinositol 3-kinase-dependent pathway and Src for Gas6-Axl mitogenic and survival activities in NIH 3T3 fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GAS6 mediates adhesion of cells expressing the receptor tyrosine kinase Axl.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling through the ARK tyrosine kinase receptor protects from apoptosis in the absence of growth stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12764109

12 December 2020

based on heuristic

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Identifiers

10.1523/JNEUROSCI.23-10-04208.2003

1 reference

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3 November 2019

1 reference

Europe PubMed Central

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3 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12764109%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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