Downregulation of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) in human hepatocellular carcinoma and their prognostic significance. (Q34206748)

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English	Downregulation of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) in human hepatocellular carcinoma and their prognostic significance.	scientific article

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26 January 2020

Downregulation of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) in human hepatocellular carcinoma and their prognostic significance (English)

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26 January 2020

hepatocellular carcinoma

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Jörn M Schattenberg

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26 January 2020

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Michael Heise

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26 January 2020

Anja Lautem

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26 January 2020

Johanna Knapstein

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26 January 2020

Maria Hoppe-Lotichius

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26 January 2020

Daniel Foltys

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26 January 2020

Nina Weiler

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26 January 2020

Anca Zimmermann

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26 January 2020

Arno Schad

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26 January 2020

Dirk Gründemann

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26 January 2020

Gerd Otto

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26 January 2020

Peter R Galle

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26 January 2020

Marcus Schuchmann

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26 January 2020

Tim Zimmermann

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26 January 2020

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22 March 2012

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26 January 2020

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26 January 2020

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26 January 2020

109

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26 January 2020

Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population

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Src family kinase inhibitor Saracatinib (AZD0530) impairs oxaliplatin uptake in colorectal cancer cells and blocks organic cation transporters

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Interaction of beta-blockers with the renal uptake transporter OCT2.

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Involvement of drug transporters in the synergistic action of FOLFOX combination chemotherapy

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5 July 2018

Expression of human organic cation transporter 3 in kidney carcinoma cell lines increases chemosensitivity to melphalan, irinotecan, and vincristine

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5 July 2018

Significance of organic cation transporter 3 (SLC22A3) expression for the cytotoxic effect of oxaliplatin in colorectal cancer.

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cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects

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Interaction of imatinib with human organic ion carriers

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5 July 2018

Hepatocellular carcinoma: epidemiology and molecular carcinogenesis

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5 July 2018

Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia

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Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines.

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5 July 2018

Human organic cation transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin.

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5 July 2018

Organic cation transporters are determinants of oxaliplatin cytotoxicity.

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5 July 2018

The Raf kinase inhibitor BAY 43-9006 reduces cellular uptake of platinum compounds and cytotoxicity in human colorectal carcinoma cell lines.

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Active transport of imatinib into and out of cells: implications for drug resistance

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5 July 2018

Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3).

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Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes

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5 July 2018

The organic cation transporter OCT2 mediates the uptake of beta-adrenoceptor antagonists across the apical membrane of renal LLC-PK(1) cell monolayers

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Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter

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5 July 2018

Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27

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5 July 2018

Transport of monoamine transmitters by the organic cation transporter type 2, OCT2.

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5 July 2018

Catecholamine transport by the organic cation transporter type 1 (OCT1)

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5 July 2018

hOCT 1 and resistance to imatinib

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Combining multiple microarrays in the presence of controlling variables.

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Modulation of gene expression and DNA adduct formation in HepG2 cells by polycyclic aromatic hydrocarbons with different carcinogenic potencies

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Factors affecting sensitivity to antitumor platinum derivatives of human colorectal tumor cell lines

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21 January 2018

OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib

1 reference

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21 January 2018

Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: higher doses of imatinib may overcome the negative impact of low OCT-1 activity

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21 January 2018

Response to transarterial chemoembolization as a biological selection criterion for liver transplantation in hepatocellular carcinoma

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https://pubmed.ncbi.nlm.nih.gov/22439694

12 December 2020

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Liver transplantation for hepatocellular carcinoma

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https://pubmed.ncbi.nlm.nih.gov/22439694

12 December 2020

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10.1186/1471-2407-12-109

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26 January 2020

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