Defibrotide for the treatment of severe hepatic veno-occlusive disease and multiorgan failure after stem cell transplantation: a multicenter, randomized, dose-finding trial (Q34207695)

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English	Defibrotide for the treatment of severe hepatic veno-occlusive disease and multiorgan failure after stem cell transplantation: a multicenter, randomized, dose-finding trial	scientific article

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scholarly article

1 reference

Europe PubMed Central

31 July 2017

Defibrotide for the treatment of severe hepatic veno-occlusive disease and multiorgan failure after stem cell transplantation: a multicenter, randomized, dose-finding trial (English)

1 reference

Europe PubMed Central

31 July 2017

multicenter clinical trial

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stem cell transplantation

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based on heuristic

inferred from title

hepatic veno-occlusive disease

1 reference

based on heuristic

inferred from title

object named as

Nancy A Kernan

13

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Paul G. Richardson

1

object named as

Paul G Richardson

1 reference

Europe PubMed Central

31 July 2017

3

object named as

Joseph H Antin

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Europe PubMed Central

31 July 2017

Joanne Kurtzberg

6

object named as

Joanne Kurtzberg

1 reference

Europe PubMed Central

31 July 2017

Georgia B. Vogelsang

10

object named as

Georgia B Vogelsang

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Europe PubMed Central

31 July 2017

author name string

Robert J Soiffer

2

1 reference

Europe PubMed Central

31 July 2017

Hajime Uno

4

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Europe PubMed Central

31 July 2017

Zhezhen Jin

5

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Europe PubMed Central

31 July 2017

Paul L Martin

7

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Europe PubMed Central

31 July 2017

Gideon Steinbach

8

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Europe PubMed Central

31 July 2017

Karen F Murray

9

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Europe PubMed Central

31 July 2017

Allen R Chen

11

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Europe PubMed Central

31 July 2017

Amrita Krishnan

12

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Europe PubMed Central

31 July 2017

David E Avigan

14

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Europe PubMed Central

31 July 2017

Thomas R Spitzer

15

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Europe PubMed Central

31 July 2017

Howard M Shulman

16

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Europe PubMed Central

31 July 2017

Donald N Di Salvo

17

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Europe PubMed Central

31 July 2017

Carolyn Revta

18

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Europe PubMed Central

31 July 2017

Diane Warren

19

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Europe PubMed Central

31 July 2017

Parisa Momtaz

20

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Europe PubMed Central

31 July 2017

Gary Bradwin

21

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Europe PubMed Central

31 July 2017

L J Wei

22

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Europe PubMed Central

31 July 2017

Massimo Iacobelli

23

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Europe PubMed Central

31 July 2017

George B McDonald

24

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Europe PubMed Central

31 July 2017

Eva C Guinan

25

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Europe PubMed Central

31 July 2017

publication date

16 February 2010

1 reference

Europe PubMed Central

31 July 2017

Biology of Blood and Marrow Transplantation

1 reference

Europe PubMed Central

31 July 2017

16

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Europe PubMed Central

31 July 2017

7

1 reference

Europe PubMed Central

31 July 2017

1005-1017

1 reference

Europe PubMed Central

31 July 2017

Personalized dosing of cyclophosphamide in the total body irradiation-cyclophosphamide conditioning regimen: a phase II trial in patients with hematologic malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Preclinical studies in support of defibrotide for the treatment of multiple myeloma and other neoplasias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Angiogenesis alteration by defibrotide: implications for its mechanism of action in severe hepatic veno-occlusive disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Systematic review of controlled clinical trials on the use of ursodeoxycholic acid for the prevention of hepatic veno-occlusive disease in hematopoietic stem cell transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Hepatic veno-occlusive disease in pediatric stem cell transplantation: impact of pre-emptive antithrombin III replacement and combined antithrombin III/defibrotide therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Sirolimus and thrombotic microangiopathy after allogeneic hematopoietic stem cell transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Hepatic venoocclusive disease in blood and bone marrow transplantation in children and young adults: incidence, risk factors, and outcome in a cohort of 241 patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Toxic injury to hepatic sinusoids: sinusoidal obstruction syndrome (veno-occlusive disease).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Hepatic veno-occlusive disease following hematopoietic stem cell transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Veno-occlusive disease of the liver after busulfan, melphalan, and thiotepa conditioning therapy: incidence, risk factors, and outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Treatment of severe veno-occlusive disease with defibrotide: compassionate use results in response without significant toxicity in a high-risk population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Treatment of hepatic venocclusive disease with recombinant human tissue plasminogen activator and heparin in 42 marrow transplant patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: a cohort study of 355 patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Venoocclusive disease of the liver: development of a model for predicting fatal outcome after marrow transplantation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Hepatic veno-occlusive disease after bone marrow transplantation. Immunohistochemical identification of the material within occluded central venules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

5 July 2018

Graft-versus-host disease prophylaxis with everolimus and tacrolimus is associated with a high incidence of sinusoidal obstruction syndrome and microangiopathy: results of the EVTAC trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

28 October 2018

Defibrotide in the prevention and treatment of veno-occlusive disease in autologous and allogeneic stem cell transplantation in children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

28 October 2018

Successful treatment of hepatic veno-occlusive disease after myeloablative allogeneic hematopoietic stem cell transplantation by early administration of a short course of methylprednisolone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

28 October 2018

Favorable response of pediatric stem cell recipients to human protein C concentrate substitution for veno-occlusive disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

28 October 2018

Multi-institutional use of defibrotide in 88 patients after stem cell transplantation with severe veno-occlusive disease and multisystem organ failure: response without significant toxicity in a high-risk population and factors predictive of outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

28 October 2018

Fludarabine induces apoptosis, activation, and allogenicity in human endothelial and epithelial cells: protective effect of defibrotide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

28 October 2018

Hepatic sinusoidal obstruction after gemtuzumab ozogamicin (Mylotarg) therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956581

28 October 2018

IBMTR Severity Index for grading acute graft-versus-host disease: retrospective comparison with Glucksberg grade

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incidence and outcome of hepatic veno-occlusive disease after blood or marrow transplantation: a prospective cohort study of the European Group for Blood and Marrow Transplantation. European Group for Blood and Marrow Transplantation Chronic Leukemi

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diagnosis of hepatic veno-occlusive disease by plasminogen activator inhibitor-1 plasma antigen levels: a prospective analysis in 350 allogeneic hematopoietic stem cell recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stem cell transplantation in children with infantile osteopetrosis is associated with a high incidence of VOD, which could be prevented with defibrotide

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defibrotide for the treatment of hepatic veno-occlusive disease in children

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclophosphamide following Targeted Oral Busulfan as Conditioning for Hematopoietic Cell Transplantation: Pharmacokinetics, Liver Toxicity, and Mortality

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prophylactic defibrotide in allogeneic stem cell transplantation: minimal morbidity and zero mortality from veno-occlusive disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Risk factors and mortality predictors of hepatic veno-occlusive disease after pediatric hematopoietic stem cell transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-acetylcysteine for hepatic veno-occlusive disease after allogeneic stem cell transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predictive markers for hepatic veno-occlusive disease after hematopoietic stem cell transplantation in adults: a prospective single center study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defibrotide for the treatment of hepatic veno-occlusive disease: results of the European compassionate-use study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defibrotide in the treatment of children with veno-occlusive disease (VOD): a retrospective multicentre study demonstrates therapeutic efficacy upon early intervention

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Venocclusive Disease of the Liver after Bone Marrow Transplantation: Diagnosis, Incidence, and Predisposing Factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute effects of defibrotide, an experimental antithrombotic agent, on fibrinolysis and blood prostanoids in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defibrotide, by enhancing prostacyclin generation, prevents endothelin-1 induced contraction in human saphenous veins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of clinical criteria for the diagnosis of veno-occlusive disease of the liver after bone marrow transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase I/II study of prostaglandin E1 for the prevention of hepatic venocclusive disease after bone marrow transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Veno-occlusive disease of the liver after marrow transplantation: histological correlates of clinical signs and symptoms

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and identification of aptamers from defibrotide that act as thrombin antagonists in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defibrotide stimulates expression of thrombomodulin in human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic veno-occlusive disease in pediatric stem cell recipients: successful treatment with continuous infusion of prostaglandin E1 and low-dose heparin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20167278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BBMT.2010.02.009

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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