A phase I clinical trial of FOLFIRI in combination with the pan-cyclin-dependent kinase (CDK) inhibitor flavopiridol (Q34214083)

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15 February 2020

title

A phase I clinical trial of FOLFIRI in combination with the pan-cyclin-dependent kinase (CDK) inhibitor flavopiridol (English)

1 reference

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15 February 2020

main subject

phase I clinical trial

0 references

author

Dana E Rathkopf

3

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15 February 2020

author name string

Mark A Dickson

1

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15 February 2020

Manish A Shah

2

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15 February 2020

Archie Tse

4

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15 February 2020

Richard D Carvajal

5

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15 February 2020

Nian Wu

6

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15 February 2020

Robert A Lefkowitz

7

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15 February 2020

Mithat Gonen

8

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15 February 2020

Lauren M Cane

9

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15 February 2020

Heather J Dials

10

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15 February 2020

Gary K Schwartz

11

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15 February 2020

publication date

21 February 2010

1 reference

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Cancer Chemotherapy and Pharmacology

15 February 2020

published in

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15 February 2020

volume

66

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15 February 2020

issue

6

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15 February 2020

page(s)

1113-1121

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https://scigraph.springernature.com/pub.10.1007/s00280-010-1269-1

15 February 2020

exact match

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cites work

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The cyclin-dependent kinase inhibitor flavopiridol potentiates the effects of topoisomerase I poisons by suppressing Rad51 expression in a p53-dependent manner

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Phase I dose-finding study of weekly docetaxel followed by flavopiridol for patients with advanced solid tumors.

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28 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20953860

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00280-010-1269-1

1 reference

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Dimensions Publication ID

15 February 2020

0 references

1 reference

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15 February 2020

1 reference