Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential (Q34217620)

31 July 2017

Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential (English)

1 reference

Correction for Zasloff et al., Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential

31 July 2017

corrigendum / erratum

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12

Scott C Weaver

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Abhijit Mishra

object named as

Abhijit Mishra

9

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author name string

Michael Zasloff

1

1 reference

31 July 2017

A Paige Adams

2

1 reference

31 July 2017

Bernard Beckerman

3

1 reference

31 July 2017

Ann Campbell

4

1 reference

31 July 2017

Ziying Han

5

1 reference

31 July 2017

Erik Luijten

6

1 reference

31 July 2017

Isaura Meza

7

1 reference

31 July 2017

Justin Julander

8

1 reference

31 July 2017

Wei Qu

10

1 reference

31 July 2017

John M Taylor

11

1 reference

31 July 2017

Gerard C L Wong

13

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31 July 2017

language of work or name

English

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publication date

19 September 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

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31 July 2017

108

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31 July 2017

15978-15983

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31 July 2017

38

1 reference

Membrane surface charge dictates the structure and function of the epithelial Na+/H+ exchanger

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Purinergic receptor functionality is necessary for infection of human hepatocytes by hepatitis delta virus and hepatitis B virus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Roles of small GTPase Rac1 in the regulation of actin cytoskeleton during dengue virus infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Role of Abl kinase and the Wave2 signaling complex in HIV-1 entry at a post-hemifusion step

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

TARP phosphorylation regulates synaptic AMPA receptors through lipid bilayers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

A broad-spectrum antiviral targeting entry of enveloped viruses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Opposing mechanisms involving RNA and lipids regulate HIV-1 Gag membrane binding through the highly basic region of the matrix domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Amphipathic DNA polymers exhibit antiviral activity against systemic murine Cytomegalovirus infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Cross-talk between Rac1 and Cdc42 GTPases regulates formation of filopodia required for dengue virus type-2 entry into HMEC-1 cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Evolution of teleost fish retroviruses: characterization of new retroviruses with cellular genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Targeting inside-out phosphatidylserine as a therapeutic strategy for viral diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Activity of T-705 in a Hamster Model of Yellow Fever Virus Infection in Comparison with That of a Chemically Related Compound, T-1106

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

The major virus-producing cell type during murine cytomegalovirus infection, the hepatocyte, is not the source of virus dissemination in the host

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Interaction between dengue virus fusion peptide and lipid bilayers depends on peptide clustering

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Experimental infection of Aedes sollicitans and Aedes taeniorhynchus with two chimeric Sindbis/Eastern equine encephalitis virus vaccine candidates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Membrane phosphatidylserine regulates surface charge and protein localization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Interaction between the human immunodeficiency virus type 1 Gag matrix domain and phosphatidylinositol-(4,5)-bisphosphate is essential for efficient gag membrane binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Chimeric Sindbis/eastern equine encephalitis vaccine candidates are highly attenuated and immunogenic in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Identification of squalamine in the plasma membrane of white blood cells in the sea lamprey, Petromyzon marinus.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Basic residues in the Mason-Pfizer monkey virus gag matrix domain regulate intracellular trafficking and capsid-membrane interactions.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

The directed cooperative assembly of proteorhodopsin into 2D and 3D polarized arrays

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Survey sequencing and comparative analysis of the elephant shark (Callorhinchus milii) genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Comparison of the inhibitory effects of interferon alfacon-1 and ribavirin on yellow fever virus infection in a hamster model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Squalamine lactate for exudative age-related macular degeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Enhancement of enveloped virus entry by phosphatidylserine.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Phosphatidylserine treatment relieves the block to retrovirus infection of cells expressing glycosylated virus receptors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Metabolism and functions of phosphatidylserine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Antiangiogenic Steroids in Human Cancer Therapy.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Early Events in the Pathogenesis of Eastern Equine Encephalitis Virus in Mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Phosphatidylserine is not the cell surface receptor for vesicular stomatitis virus.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Efficacy of post-exposure treatment of yellow fever with ribavirin in a hamster model of the disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

The natural antibody repertoire of sharks and humans recognizes the potential universe of antigens

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in situ hybridization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

A phase I/IIA trial of continuous five-day infusion of squalamine lactate (MSI-1256F) plus carboplatin and paclitaxel in patients with advanced non-small cell lung cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Insider information: what viruses tell us about endocytosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

A Phase I and pharmacokinetic study of squalamine, an aminosterol angiogenesis inhibitor.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Vigorous innate and virus-specific cytotoxic T-lymphocyte responses to murine cytomegalovirus in the submaxillary salivary gland

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Effect of squalamine on iris neovascularization in monkeys

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Experimental yellow fever virus infection in the Golden hamster (Mesocricetus auratus). II. Pathology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Experimental yellow fever virus infection in the Golden Hamster (Mesocricetus auratus). I. Virologic, biochemical, and immunologic studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Squalamine inhibits angiogenesis and solid tumor growth in vivo and perturbs embryonic vasculature.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

The aminosterol antibiotic squalamine permeabilizes large unilamellar phospholipid vesicles.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Squalamine: an aminosterol antibiotic from the shark

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Structure of the novel steroidal antibiotic squalamine determined by two-dimensional NMR spectroscopy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179074

Squalamine and cisplatin block angiogenesis and growth of human ovarian cancer cells with or without HER-2 gene overexpression

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108558108

Antiangiogenic treatment delays chondrocyte maturation and bone formation during limb skeletogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108558108

Regression of retinopathy by squalamine in a mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108558108

Squalamine is not a proton ionophore.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108558108

Vaccinia virus uses macropinocytosis and apoptotic mimicry to enter host cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108558108

Semliki Forest virus mRNA capping enzyme requires association with anionic membrane phospholipids for activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108558108

Viroporin-mediated membrane permeabilization. Pore formation by nonstructural poliovirus 2B protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108558108

The hamster as an animal model for eastern equine encephalitis--and its use in studies of virus entrance into the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108558108

Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108558108

Squalamine improves retinal neovascularization

21 January 2018

1 reference

12 December 2020

Squalamine treatment of human tumors in nu/nu mice enhances platinum-based chemotherapies

1 reference

12 December 2020

Potentiation of platinum antitumor effects in human lung tumor xenografts by the angiogenesis inhibitor squalamine: effects on tumor neovascularization

1 reference

12 December 2020

A phase I and pharmacokinetic study of squalamine, a novel antiangiogenic agent, in patients with advanced cancers

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1108558108

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference