Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis (Q34218443)

31 July 2017

Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis (English)

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31 July 2017

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4

Janice J Kim

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31 July 2017

6

Elena F Verdu

1 reference

31 July 2017

Kyle L Flannigan

1

1 reference

31 July 2017

Terence A Agbor

2

1 reference

31 July 2017

Rory W Blackler

3

1 reference

31 July 2017

Waliul I Khan

5

1 reference

31 July 2017

Jose G P Ferraz

7

1 reference

31 July 2017

John L Wallace

8

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31 July 2017

language of work or name

English

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publication date

3 September 2014

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Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

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31 July 2017

111

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31 July 2017

37

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31 July 2017

13559-13564

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Interleukin-10 receptor signaling in innate immune cells regulates mucosal immune tolerance and anti-inflammatory macrophage function

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Anti-inflammatory and cytoprotective actions of hydrogen sulfide: translation to therapeutics.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Enhanced synthesis and diminished degradation of hydrogen sulfide in experimental colitis: a site-specific, pro-resolution mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Production and physiological effects of hydrogen sulfide.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates immune responses and reduces the severity of intestinal inflammation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

IL-10R polymorphisms are associated with very-early-onset ulcerative colitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Inhaled hydrogen sulfide prevents endotoxin-induced systemic inflammation and improves survival by altering sulfide metabolism in mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Hyperhomocysteinemia impairs endothelium-derived hyperpolarizing factor-mediated vasorelaxation in transgenic cystathionine beta synthase-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Inborn errors of cobalamin absorption and metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

IL-10 administration reduces PGE-2 levels and promotes CR3-mediated clearance of Escherichia coli K1 by phagocytes in meningitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Physiological and pathophysiological roles of hydrogen sulfide in the gastrointestinal tract

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Increasing incidence of paediatric inflammatory bowel disease in Ontario, Canada: evidence from health administrative data.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

B-vitamin deficiency causes hyperhomocysteinemia and vascular cognitive impairment in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Lack of effects of acemetacin on signalling pathways for leukocyte adherence may explain its gastrointestinal safety.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Hydrogen sulfide inhibits myocardial injury induced by homocysteine in rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

A protective role of hydrogen sulfide against oxidative stress in rat gastric mucosal epithelium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Nutrition assessment of patients with inflammatory bowel disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Enhanced activity of a hydrogen sulphide-releasing derivative of mesalamine (ATB-429) in a mouse model of colitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Elevated levels of homocysteine compromise blood-brain barrier integrity in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Homocysteine and methylmalonic acid: markers to predict and avoid toxicity from pemetrexed therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

The vasorelaxant effect of H(2)S as a novel endogenous gaseous K(ATP) channel opener

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Interleukin 10 (Tenovil) in the prevention of postoperative recurrence of Crohn's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Clinicopathologic study of dextran sulfate sodium experimental murine colitis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Characterization of the enzymic capacity for cysteine desulphhydration in liver and kidney of the rat

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Homocysteinemia and B vitamin status among adult patients with inflammatory bowel disease: a one-year prospective follow-up study

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1413390111

Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1413390111

Hyperhomocysteinemia as a risk factor for deep-vein thrombosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1413390111

Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1413390111

Understanding the cancer biology universe: enigmas, context and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1413390111

Homocysteine levels in A/J and C57BL/6J mice: genetic, diet, gender, and parental effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1413390111

Gastric inflammatory fibroid polyp manifesting massive bleeding and marked morphological changes for a short period

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1413390111

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1413390111

Hydrogen sulfide attenuates the inflammatory response in a mouse burn injury model.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

Low vitamin B(6) plasma levels, a risk factor for thrombosis, in inflammatory bowel disease: role of inflammation and correlation with acute phase reactants

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169975

IL-10 deficiency increases superoxide and endothelial dysfunction during inflammation

28 October 2018

1 reference

12 December 2020

Inflammatory bowel disease: lessons from the IL-10 gene-deficient mouse

1 reference

12 December 2020

A Gly15Arg mutation in the interleukin-10 gene reduces secretion of interleukin-10 in Crohn disease

1 reference

12 December 2020

The effects of vitamin B6 deficiency on the bone marrow of the rat1

1 reference

12 December 2020

Relationship between arachidonic acid metabolism, myeloperoxidase activity and leukocyte infiltration in a rat model of inflammatory bowel disease

1 reference

12 December 2020

Hapten-induced chronic colitis in the rat: alternatives to trinitrobenzene sulfonic acid

1 reference

12 December 2020

Impaired inhibitory effect of interleukin-10 on the balance between matrix metalloproteinase-9 and its inhibitor in mononuclear cells from hyperhomocysteinemic subjects

1 reference

12 December 2020

Pro-inflammatory bone marrow milieu in patients with chronic idiopathic neutropenia is associated with impaired local production of interleukin-10

1 reference

12 December 2020

Hydrogen sulfide enhances ulcer healing in rats

1 reference

12 December 2020

Regulatory effects of hydrogen sulfide on IL-6, IL-8 and IL-10 levels in the plasma and pulmonary tissue of rats with acute lung injury

1 reference

12 December 2020

Hydrogen sulphide synthesis in the rat and mouse gastrointestinal tract

1 reference

12 December 2020

Eukaryotic and prokaryotic contributions to colonic hydrogen sulfide synthesis

1 reference

12 December 2020

Inhibition of hydrogen sulfide generation contributes to lung injury after experimental orthotopic lung transplantation

1 reference

12 December 2020

Homocysteine in inflammatory bowel disease: a risk factor for thromboembolic complications?

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1413390111

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31 July 2017

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31 July 2017

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