Combretastatin A-4 inhibits cell growth and metastasis in bladder cancer cells and retards tumour growth in a murine orthotopic bladder tumour model (Q34219595)

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English	Combretastatin A-4 inhibits cell growth and metastasis in bladder cancer cells and retards tumour growth in a murine orthotopic bladder tumour model	scientific article

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scholarly article

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Europe PubMed Central

31 July 2017

Combretastatin A-4 inhibits cell growth and metastasis in bladder cancer cells and retards tumour growth in a murine orthotopic bladder tumour model (English)

1 reference

Europe PubMed Central

31 July 2017

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based on heuristic

inferred from title

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based on heuristic

inferred from title

6

object named as

Yi-Wen Liu

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Europe PubMed Central

31 July 2017

author name string

Cheng-Huang Shen

1

1 reference

Europe PubMed Central

31 July 2017

Jia-Jen Shee

2

1 reference

Europe PubMed Central

31 July 2017

Jin-Yi Wu

3

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Europe PubMed Central

31 July 2017

Yi-Wen Lin

4

1 reference

Europe PubMed Central

31 July 2017

Jiann-Der Wu

5

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Europe PubMed Central

31 July 2017

language of work or name

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publication date

1 August 2010

1 reference

Europe PubMed Central

31 July 2017

British Journal of Pharmacology

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Europe PubMed Central

31 July 2017

160

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Europe PubMed Central

31 July 2017

8

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Europe PubMed Central

31 July 2017

2008-2027

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Europe PubMed Central

31 July 2017

The aurora B kinase inhibitor AZD1152 sensitizes cancer cells to fractionated irradiation and induces mitotic catastrophe

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5 July 2018

Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer

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5 July 2018

Cancer statistics, 2009

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5 July 2018

The global burden of urinary bladder cancer.

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5 July 2018

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

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5 July 2018

Apoptosis and non-apoptotic deaths in cancer development and treatment response

1 reference

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5 July 2018

Histopathological characterization of a syngeneic orthotopic murine bladder cancer model.

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5 July 2018

The microtubule-targeting agent CA4P regresses leukemic xenografts by disrupting interaction with vascular cells and mitochondrial-dependent cell death

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5 July 2018

BubR1 is required for a sustained mitotic spindle checkpoint arrest in human cancer cells treated with tubulin-targeting pyrrolo-1,5-benzoxazepines.

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5 July 2018

Bladder cancer angiogenesis and metastasis--translation from murine model to clinical trial

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5 July 2018

Combretastatin A4-induced differential cytotoxicity and reduced metastatic ability by inhibition of AKT function in human gastric cancer cells

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5 July 2018

Epidemiology of urinary bladder cancer: from tumor development to patient's death

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5 July 2018

Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells

1 reference

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5 July 2018

Anti-vascular agent Combretastatin A-4-P modulates hypoxia inducible factor-1 and gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958646

5 July 2018

Combretastatin CA-4 and combretastatin derivative induce mitotic catastrophe dependent on spindle checkpoint and caspase-3 activation in non-small cell lung cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958646

5 July 2018

Dual-track pathway of bladder carcinogenesis: practical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958646

5 July 2018

Novel combretastatin analogues endowed with antitumor activity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958646

5 July 2018

Akt/PKB signaling in cancer: a function in cell motility and invasion

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958646

5 July 2018

Complex networks orchestrate epithelial-mesenchymal transitions

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5 July 2018

Combretastatin A4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958646

5 July 2018

Phase I trial of combretastatin a-4 phosphate with carboplatin

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958646

5 July 2018

The tubulin-binding agent combretastatin A-4-phosphate arrests endothelial cells in mitosis and induces mitotic cell death

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5 July 2018

BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.

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5 July 2018

Cell death by mitotic catastrophe: a molecular definition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958646

5 July 2018

Cardiovascular safety profile of combretastatin a4 phosphate in a single-dose phase I study in patients with advanced cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958646

5 July 2018

Phase I trial of the antivascular agent combretastatin A4 phosphate on a 5-day schedule to patients with cancer: magnetic resonance imaging evidence for altered tumor blood flow

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5 July 2018

Microtubules, microtubule-interfering agents and apoptosis.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958646

5 July 2018

Role of angiogenesis in tumor growth and metastasis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958646

5 July 2018

Combretastatin-A4 prodrug induces mitotic catastrophe in chronic lymphocytic leukemia cell line independent of caspase activation and poly(ADP-ribose) polymerase cleavage

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5 July 2018

Diagnosis and management of superficial bladder cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958646

5 July 2018

Bridging cytoskeletal intersections.

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5 July 2018

The effect of antimicrotubule agents on signal transduction pathways of apoptosis: a review

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5 July 2018

MPM-2 antibody-reactive phosphorylations can be created in detergent-extracted cells by kinetochore-bound and soluble kinases.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958646

5 July 2018

Overexpression of MDM-2 mRNA and mutation of the p53 tumor suppressor gene in bladder carcinoma cell lines

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5 July 2018

Concepts in causality: chemically induced human urinary bladder cancer

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5 July 2018

Monoclonal antibodies to mitotic cells

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5 July 2018

Establishment and characterization of a human urinary bladder carcinoma cell line (TSGH-8301)

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5 July 2018

Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4.

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5 July 2018

Antineoplastic agents. 291. Isolation and synthesis of combretastatins A-4, A-5, and A-6(1a)

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21 January 2018

Combretastatin A-4 phosphate as a tumor vascular-targeting agent: early effects in tumors and normal tissues.

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28 October 2018

Chemoprevention of superficial bladder cancer

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Phase I trial of intravesical docetaxel in the management of superficial bladder cancer refractory to standard intravesical therapy

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Antineoplastic agents 322. synthesis of combretastatin A-4 prodrugs

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https://pubmed.ncbi.nlm.nih.gov/20649598

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Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature

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https://pubmed.ncbi.nlm.nih.gov/20649598

12 December 2020

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Mitotic phosphorylation of DNA topoisomerase II alpha by protein kinase CK2 creates the MPM-2 phosphoepitope on Ser-1469

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Paclitaxel and docetaxel in the treatment of breast cancer

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https://pubmed.ncbi.nlm.nih.gov/20649598

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Identifiers

10.1111/J.1476-5381.2010.00861.X

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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