Selenium, selenoproteins and the thyroid gland: interactions in health and disease (Q34225316)

31 July 2017

Selenium, selenoproteins and the thyroid gland: interactions in health and disease (English)

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31 July 2017

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Lutz Schomburg

1

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31 July 2017

18 October 2011

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31 July 2017

12

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Nature Reviews Endocrinology

inferred from page(s)

published in

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31 July 2017

8

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31 July 2017

160-171

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31 July 2017

3

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https://scigraph.springernature.com/pub.10.1038/nrendo.2011.174

31 July 2017

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Selenium, the thyroid, and the endocrine system.

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Hepatic deiodinase activity is dispensable for the maintenance of normal circulating thyroid hormone levels in mice

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Triumphs of the thyroid despite lesser conversion

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Evidence for specific selenium target tissues and new biologically important selenoproteins.

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Hierarchical regulation of selenoprotein expression and sex-specific effects of selenium

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Differential regulation of rat liver selenoprotein mRNAs in selenium deficiency.

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Tissue-specific regulation of selenoenzyme gene expression during selenium deficiency in rats.

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Differential selenium-dependent expression of type I 5'-deiodinase and glutathione peroxidase in the porcine epithelial kidney cell line LLC-PK1.

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Selenium and endocrine systems

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Regulation of selenoproteins

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Responsiveness of selenoproteins to dietary selenium

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Synthesis and metabolism of thyroid hormones is preferentially maintained in selenium-deficient transgenic mice

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'Linkage analysis of thyroid antibody production: evidence for shared susceptibility to clinical autoimmune thyroid disease

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Endocrine autoimmune disease: genetics become complex

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A compendium of genome-wide associations for cancer: critical synopsis and reappraisal

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Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations

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Selenoprotein function and muscle disease

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Disorders of selenium metabolism and selenoprotein function

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Selenoprotein N: an endoplasmic reticulum glycoprotein with an early developmental expression pattern

21 January 2018

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Satellite cell loss and impaired muscle regeneration in selenoprotein N deficiency

21 January 2018

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Mutations disrupting selenocysteine formation cause progressive cerebello-cerebral atrophy

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Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration

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A novel RNA binding protein, SBP2, is required for the translation of mammalian selenoprotein mRNAs

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SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress.

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Mutations in SECISBP2 result in abnormal thyroid hormone metabolism

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Clinical and molecular characterization of a novel selenocysteine insertion sequence-binding protein 2 (SBP2) gene mutation (R128X).

21 January 2018

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Selenium supplementation fails to correct the selenoprotein synthesis defect in subjects with SBP2 gene mutations.

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Selenoprotein-related disease in a young girl caused by nonsense mutations in the SBP2 gene

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Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans

21 January 2018

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21 January 2018

Soils and geomedicine

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Selenium supplementation: does soil supplementation help and why?

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High-selenium yeast supplementation in free-living North American men: no effect on thyroid hormone metabolism or body composition

21 January 2018

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Effects of selenomethionine supplementation on selenium status and thyroid hormone concentrations in healthy adults.

21 January 2018

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Selenium substitution has no direct effect on thyroid hormone metabolism in critically ill patients

21 January 2018

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Influence of selenium supplements on the post-traumatic alterations of the thyroid axis: a placebo-controlled trial

21 January 2018

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The influence of selenium on immune responses

21 January 2018

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Selenium replacement in patients with severe systemic inflammatory response syndrome improves clinical outcome.

21 January 2018

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Down-regulation of the hepatic selenoprotein biosynthesis machinery impairs selenium metabolism during the acute phase response in mice.

21 January 2018

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Effects of high doses of selenium, as sodium selenite, in septic shock: a placebo-controlled, randomized, double-blind, phase II study

21 January 2018

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Thyroid hormones regulate selenoprotein expression and selenium status in mice

21 January 2018

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Serum selenium versus lymphocyte subsets and markers of disease progression and inflammatory response in human immunodeficiency virus-1 infection

21 January 2018

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Serum selenium in acute infections

21 January 2018

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Immunonutrition and critical illness: an update

21 January 2018

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Rationale and design of the pediatric critical illness stress-induced immune suppression (CRISIS) prevention trial

21 January 2018

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Trace element supplementation in parenteral nutrition: pharmacy, posology, and monitoring guidance

21 January 2018

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Concentration of selenium in the whole blood and the thyroid tissue of patients with various thyroid diseases.

21 January 2018

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Effects of a six month treatment with selenomethionine in patients with autoimmune thyroiditis

21 January 2018

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Selenium treatment in autoimmune thyroiditis: 9-month follow-up with variable doses.

21 January 2018

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No immunological benefit of selenium in consecutive patients with autoimmune thyroiditis

21 January 2018

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The influence of selenium supplementation on postpartum thyroid status in pregnant women with thyroid peroxidase autoantibodies

21 January 2018

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21 January 2018

Graves' ophthalmopathy

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Consensus statement of the European group on Graves' orbitopathy (EUGOGO) on management of Graves' orbitopathy

21 January 2018

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Selenium and the course of mild Graves' orbitopathy

21 January 2018

1 reference

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Serum selenium and diabetes in U.S. adults

21 January 2018

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Higher selenium status is associated with adverse blood lipid profile in British adults

21 January 2018

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Effect of supplementation with high-selenium yeast on plasma lipids: a randomized trial.

21 January 2018

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Dietary selenium modulates activation and differentiation of CD4+ T cells in mice through a mechanism involving cellular free thiols

21 January 2018

1 reference

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Selenium upregulates CD4(+)CD25(+) regulatory T cells in iodine-induced autoimmune thyroiditis model of NOD.H-2(h4) mice.

21 January 2018

1 reference

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The anti-inflammatory effects of selenium are mediated through 15-deoxy-Delta12,14-prostaglandin J2 in macrophages

21 January 2018

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Focus on mammalian thioredoxin reductases--important selenoproteins with versatile functions

21 January 2018

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The biological significance of methionine sulfoxide stereochemistry

21 January 2018

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Oxidative stress can alter the antigenicity of immunodominant peptides

21 January 2018

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A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

21 January 2018

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Genetic variation in selenoprotein S influences inflammatory response

21 January 2018

1 reference

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Polymorphisms in the selenoprotein S and 15-kDa selenoprotein genes are associated with altered susceptibility to colorectal cancer

21 January 2018

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Selenoprotein K knockout mice exhibit deficient calcium flux in immune cells and impaired immune responses

21 January 2018

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Selenium attenuates pro-inflammatory gene expression in macrophages

21 January 2018

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Selenium controls the sex-specific immune response and selenoprotein expression during the acute-phase response in mice

21 January 2018

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Crystal Structure of the Human Lymphoid Tyrosine Phosphatase Catalytic Domain: Insights into Redox Regulation,

21 January 2018

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Effects of 12 months treatment with L-selenomethionine on serum anti-TPO Levels in Patients with Hashimoto's thyroiditis.

21 January 2018

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Selenium supplementation does not decrease thyroid peroxidase antibody concentration in children and adolescents with autoimmune thyroiditis.

21 January 2018

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The genetics of autoimmune thyroid disease

21 January 2018

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NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic Cells

21 January 2018

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Effects of Long-Term Selenium Supplementation on the Incidence of Type 2 Diabetes

21 January 2018

1 reference

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Glutathione peroxidase degrades intracellular hydrogen peroxide and thereby inhibits intracellular protein iodination in thyroid epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Effect of iodine intake on thyroid diseases in China

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Selenium, systemic immune response syndrome, sepsis, and outcome in critically ill patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Selenium depletion in patients with gastrointestinal diseases: are there any predictive factors?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Selenium deficiency and thyroid fibrosis. A key role for macrophages and transforming growth factor beta (TGF-beta)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Effects of selenium deficiency on tissue selenium content, deiodinase activity, and thyroid hormone economy in the rat during development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

mRNA stability and selenocysteine insertion sequence efficiency rank gastrointestinal glutathione peroxidase high in the hierarchy of selenoproteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Randomized controlled trial of the effect of selenium supplementation on thyroid function in the elderly in the United Kingdom

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Selenium and iodine supplementation: effect on thyroid function of older New Zealanders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Selenium and iodine supplementation of rural Tibetan children affected by Kashin-Beck osteoarthropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Selenium: an essential element for immune function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Selenium in the Immune System

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Selenium and the thyroid: a close-knit connection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Time course and relationship between plasma selenium concentrations, systemic inflammatory response, sepsis, and multiorgan failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Selenium in Intensive Care (SIC): results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

A LARGE-BOLUS INJECTION, BUT NOT CONTINUOUS INFUSION OF SODIUM SELENITE IMPROVES OUTCOME IN PERITONITIS

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Selenium in intensive care (SIC) study: the XX files are still unresolved

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Selenium Deficiency and Viral Infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Nutritional support for critically ill children

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Effectiveness of selenium supplements in a low-selenium area of China

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Effects of chemical form of selenium on plasma biomarkers in a high-dose human supplementation trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

An increase in selenium intake improves immune function and poliovirus handling in adults with marginal selenium status.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

Functions and evolution of selenoprotein methionine sulfoxide reductases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.174

The Thyrotropin Receptor and the Regulation of Thyrocyte Function and Growth*

31 March 2020

1 reference

12 December 2020

Influence of physiological dietary selenium supplementation on the natural course of autoimmune thyroiditis

1 reference

12 December 2020

Changes in the concentrations of plasma selenium and selenoproteins after minor elective surgery: further evidence for a negative acute phase response?

1 reference

12 December 2020

Inter-relationships between selenium and thyroid hormone metabolism in the rat and man

1 reference

12 December 2020

Genetic susceptibility in thyroid autoimmunity.

1 reference

12 December 2020

The glutathione peroxidases

1 reference

12 December 2020

A large-bolus injection, but not continuous infusion of sodium selenite improves outcome in peritonitis

1 reference

12 December 2020

Reduced platelet glutathione peroxidase activity and serum selenium concentration in atopic asthmatic patients.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRENDO.2011.174

1 reference

31 July 2017

1 reference

PubMed ID

22009156