Conformational changes in HIV-1 gp41 in the course of HIV-1 envelope glycoprotein-mediated fusion and inactivation. (Q34225654)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16156659%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

Conformational changes in HIV-1 gp41 in the course of HIV-1 envelope glycoprotein-mediated fusion and inactivation (English)

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4

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5

Robert Blumenthal

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6 January 2020

author name string

Antony S Dimitrov

series ordinal

1

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John M Louis

series ordinal

2

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6 January 2020

Carole A Bewley

series ordinal

3

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6 January 2020

language of work or name

English

0 references

publication date

1 September 2005

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6 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16156659%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

volume

44

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6 January 2020

issue

37

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6 January 2020

page(s)

12471-12479

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Differential inhibition of HIV-1 and SIV envelope-mediated cell fusion by C34 peptides derived from the C-terminal heptad repeat of gp41 from diverse strains of HIV-1, HIV-2, and SIV.

6 January 2020

cites work

1 reference

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Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

28 July 2018

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Temperature-dependent intermediates in HIV-1 envelope glycoprotein-mediated fusion revealed by inhibitors that target N- and C-terminal helical regions of HIV-1 gp41.

28 July 2018

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Binding of the 2F5 monoclonal antibody to native and fusion-intermediate forms of human immunodeficiency virus type 1 gp41: implications for fusion-inducing conformational changes.

28 July 2018

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The HIV Env-mediated fusion reaction

28 July 2018

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Direct evidence that C-peptide inhibitors of human immunodeficiency virus type 1 entry bind to the gp41 N-helical domain in receptor-activated viral envelope

28 July 2018

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Targeting therapeutics to an exposed and conserved binding element of the HIV-1 fusion protein

28 July 2018

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Covalent trimers of the internal N-terminal trimeric coiled-coil of gp41 and antibodies directed against them are potent inhibitors of HIV envelope-mediated cell fusion.

28 July 2018

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HIV-1 envelope proteins complete their folding into six-helix bundles immediately after fusion pore formation

28 July 2018

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The prefusogenic intermediate of HIV-1 gp41 contains exposed C-peptide regions.

28 July 2018

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Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodies

28 July 2018

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Antigenic properties of the human immunodeficiency virus transmembrane glycoprotein during cell-cell fusion

28 July 2018

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Dissection of human immunodeficiency virus type 1 entry with neutralizing antibodies to gp41 fusion intermediates

28 July 2018

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Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.

28 July 2018

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Peptides corresponding to the heptad repeat motifs in the transmembrane protein (gp41) of human immunodeficiency virus type 1 elicit antibodies to receptor-activated conformations of the envelope glycoprotein

28 July 2018

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Design and properties of N(CCG)-gp41, a chimeric gp41 molecule with nanomolar HIV fusion inhibitory activity

28 July 2018

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Protein design of an HIV-1 entry inhibitor

28 July 2018

1 reference

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HIV-1 membrane fusion: targets of opportunity

28 July 2018

1 reference

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Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion

28 July 2018

1 reference

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Recognition by human monoclonal antibodies of free and complexed peptides representing the prefusogenic and fusogenic forms of human immunodeficiency virus type 1 gp41

28 July 2018

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Monomer-trimer equilibrium of the ectodomain of SIV gp41: insight into the mechanism of peptide inhibition of HIV infection

28 July 2018

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Structural basis for membrane fusion by enveloped viruses

28 July 2018

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Evidence that a prominent cavity in the coiled coil of HIV type 1 gp41 is an attractive drug target

28 July 2018

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A conformation-specific monoclonal antibody reacting with fusion-active gp41 from the human immunodeficiency virus type 1 envelope glycoprotein.

28 July 2018

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Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41

28 July 2018

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

28 July 2018

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HIV entry and its inhibition

28 July 2018

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Capture of an early fusion-active conformation of HIV-1 gp41

28 July 2018

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Dilation of the human immunodeficiency virus-1 envelope glycoprotein fusion pore revealed by the inhibitory action of a synthetic peptide from gp41

28 July 2018

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Conformational changes in cell surface HIV-1 envelope glycoproteins are triggered by cooperation between cell surface CD4 and co-receptors

28 July 2018

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Atomic structure of the ectodomain from HIV-1 gp41

28 July 2018

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28 July 2018

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Characterization of stable Chinese hamster ovary cells expressing wild-type, secreted, and glycosylphosphatidylinositol-anchored human immunodeficiency virus type 1 envelope glycoprotein.

28 July 2018

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Epitope exposure on functional, oligomeric HIV-1 gp41 molecules

28 July 2018

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Biological and immunological properties of human immunodeficiency virus type 1 envelope glycoprotein: analysis of proteins with truncations and deletions expressed by recombinant vaccinia viruses

28 July 2018

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A synthetic peptide inhibitor of human immunodeficiency virus replication: correlation between solution structure and viral inhibition

28 July 2018

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The stability of the intact envelope glycoproteins is a major determinant of sensitivity of HIV/SIV to peptidic fusion inhibitors

28 July 2018

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Rapid and automated fluorescence-linked immunosorbent assay for high-throughput screening of HIV-1 fusion inhibitors targeting gp41.

28 October 2018

1 reference

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Design of a novel peptide inhibitor of HIV fusion that disrupts the internal trimeric coiled-coil of gp41.

28 October 2018

1 reference

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HIV-1 gp41 six-helix bundle formation occurs rapidly after the engagement of gp120 by CXCR4 in the HIV-1 Env-mediated fusion process

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1314968

Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease

28 October 2018

1 reference

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Core structure of gp41 from the HIV envelope glycoprotein

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1314968

A trimeric structural domain of the HIV-1 transmembrane glycoprotein.

28 October 2018

1 reference

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Steric accessibility of the HIV-1 gp41 N-trimer region

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16156659

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Determination of the HIV-1 gp41 fusogenic core conformation modeled by synthetic peptides: applicable for identification of HIV-1 fusion inhibitors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16156659

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/BI051092D

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16156659%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16156659%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

PubMed publication ID

16156659

1 reference