G-proteins in growth and apoptosis: lessons from the heart (Q34226037)

31 July 2017

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title

G-proteins in growth and apoptosis: lessons from the heart (English)

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31 July 2017

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Adams JW

1

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31 July 2017

Brown JH

series ordinal

2

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31 July 2017

language of work or name

English

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publication date

1 March 2001

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31 July 2017

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31 July 2017

20

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31 July 2017

13

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31 July 2017

1626-1634

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204275

31 July 2017

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cites work

Prostaglandin F2 alpha stimulates hypertrophic growth of cultured neonatal rat ventricular myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Cardiomyocyte apoptosis induced by Galphaq signaling is mediated by permeability transition pore formation and activation of the mitochondrial death pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Tyrosine kinase and c-Jun NH2-terminal kinase mediate hypertrophic responses to prostaglandin F2alpha in cultured neonatal rat ventricular myocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Adenoviral delivery of E2F-1 directs cell cycle reentry and p53-independent apoptosis in postmitotic adult myocardium in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Beta-adrenergic receptor blockade arrests myocyte damage and preserves cardiac function in the transgenic G(salpha) mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Transgenic mice with cardiac overexpression of alpha1B-adrenergic receptors. In vivo alpha1-adrenergic receptor-mediated regulation of beta-adrenergic signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Induction of the skeletal alpha-actin gene in alpha 1-adrenoceptor-mediated hypertrophy of rat cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Myocardial-directed overexpression of the human beta(1)-adrenergic receptor in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Radioimmunochemical quantification of Gi alpha in right and left ventricles from patients with ischaemic and dilated cardiomyopathy and predominant left ventricular failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Increase of Gi alpha in human hearts with dilated but not ischemic cardiomyopathy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

The effect of pertussis toxin on beta-adrenoceptor responses in isolated cardiac myocytes from noradrenaline-treated guinea-pigs and patients with cardiac failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

The beta(2)-adrenergic receptor delivers an antiapoptotic signal to cardiac myocytes through G(i)-dependent coupling to phosphatidylinositol 3'-kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Mechanism of beta-adrenergic receptor desensitization in cardiac hypertrophy is increased beta-adrenergic receptor kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Angiotensin II activates programmed myocyte cell death in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

p38 mitogen-activated protein kinase pathway protects adult rat ventricular myocytes against beta -adrenergic receptor-stimulated apoptosis. Evidence for Gi-dependent activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the beta-adrenergic pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Opposing effects of beta(1)- and beta(2)-adrenergic receptors on cardiac myocyte apoptosis : role of a pertussis toxin-sensitive G protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Transgenic Galphaq overexpression induces cardiac contractile failure in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Morphological characterization of cardiomyocytes isolated from a transplantable cardiac tumor derived from transgenic mouse atria (AT-1 cells).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Autonomous and growth factor-induced hypertrophy in cultured neonatal mouse cardiac myocytes. Comparison with rat.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Gq signaling in cardiac adaptation and maladaptation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Phorbol esters induce immediate-early genes and activate cardiac gene transcription in neonatal rat myocardial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Chronic ETA receptor blockade attenuates cardiac hypertrophy independently of blood pressure effects in renovascular hypertensive rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Overexpression of Bax Protein and Enhanced Apoptosis in the Left Ventricle of Spontaneously Hypertensive Rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Apoptosis of cardiac myocytes in Gsalpha transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Gelsolin binding and cellular presentation of lysophosphatidic acid

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Effects of ACE inhibition on cardiomyocyte apoptosis in dogs with heart failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Acute pressure overload could induce hypertrophic responses in the heart of angiotensin II type 1a knockout mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Norepinephrine spillover to plasma in patients with congestive heart failure: evidence of increased overall and cardiorenal sympathetic nervous activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Endothelin ETA receptor regulates signaling and ANF gene expression via multiple G protein-linked pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Endothelin-1 induces hypertrophy with enhanced expression of muscle-specific genes in cultured neonatal rat cardiomyocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Adverse effects of chronic endogenous sympathetic drive induced by cardiac GS alpha overexpression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Cardiomyopathy induced by cardiac Gs alpha overexpression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Cardiac transgenic and gene-targeted mice as models of cardiac hypertrophy and failure: a problem of (new) riches

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Angiotensin II induces apoptosis of adult ventricular myocytes in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

M-CAT, CArG, and Sp1 Elements Are Required for -Adrenergic Induction of the Skeletal -Actin Promoter during Cardiac Myocyte Hypertrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

The cardiomyopathy of overload: an unnatural growth response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Mechanical stretch induces hypertrophic responses in cardiac myocytes of angiotensin II type 1a receptor knockout mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Prostaglandin F2 alpha induces cardiac myocyte hypertrophy in vitro and cardiac growth in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Increased cardiomyocyte apoptosis during the transition to heart failure in the spontaneously hypertensive rat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: critical role for expression level

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Ca(2+)-activated but not G protein-mediated inositol phosphate responses in rat neonatal cardiomyocytes involve inositol 1,4, 5-trisphosphate generation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Constitutively active mutants of the alpha(1a)- and the alpha(1b)-adrenergic receptor subtypes reveal coupling to different signaling pathways and physiological responses in rat cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Transient cardiac expression of constitutively active Galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

MEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Heart failure and endothelin receptor antagonists

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Cardiotrophic Effects of Protein Kinase C : Analysis by In Vivo Modulation of PKC Translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Peptide growth factors can provoke "fetal" contractile protein gene expression in rat cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Dissociation of p44 and p42 mitogen-activated protein kinase activation from receptor-induced hypertrophy in neonatal rat ventricular myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

M1 muscarinic receptors heterologously expressed in cardiac myocytes mediate Ras-dependent changes in gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Enhanced myocardial relaxation in vivo in transgenic mice overexpressing the beta2-adrenergic receptor is associated with reduced phospholamban protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Signaling properties and functions of two distinct cardiomyocyte protease-activated receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Signal transduction pathways of angiotensin II--induced c-fos gene expression in cardiac myocytes in vitro. Roles of phospholipid-derived second messengers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

beta-Adrenergic pathway induces apoptosis through calcineurin activation in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Decompensation of pressure-overload hypertrophy in G alpha q-overexpressing mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Sphingosylphosphorylcholine induces a hypertrophic growth response through the mitogen-activated protein kinase signaling cascade in rat neonatal cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

beta-adrenergic stimulation causes cardiocyte apoptosis: influence of tachycardia and hypertrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Transcriptional activation of the cardiac myosin light chain 2 and atrial natriuretic factor genes by protein kinase C in neonatal rat ventricular myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Norepinephrine-stimulated hypertrophy of cultured rat myocardial cells is an alpha 1 adrenergic response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Stimulation of hypertrophy of cultured neonatal rat heart cells through an alpha 1-adrenergic receptor and induction of beating through an alpha 1- and beta 1-adrenergic receptor interaction. Evidence for independent regulation of growth and beating

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Myocyte hypertrophy in neonatal rat heart cultures and its regulation by serum and by catecholamines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Beta-protein kinase C and hypertrophic signaling in human heart failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Protein kinase C isoform diversity in the heart

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

"Stress-responsive" mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Transgenic overexpression of constitutively active protein kinase C epsilon causes concentric cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Endothelin-3 induces hypertrophy of cardiomyocytes by the endogenous endothelin-1-mediated mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Influence of the angiotensin II antagonist valsartan on left ventricular hypertrophy in patients with essential hypertension

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Determinants of the cardiomyopathic phenotype in chimeric mice overexpressing cardiac Gsalpha.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Mechanical stress activates protein kinase cascade of phosphorylation in neonatal rat cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Hypertrophic responses of cardiomyocytes induced by endothelin-1 through the protein kinase C-dependent but Src and Ras-independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Beta-adrenergic receptor subtypes differentially affect apoptosis in adult rat ventricular myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Effects of angiotensin-converting enzyme inhibition and angiotensin II AT1 receptor antagonism on cardiac parameters in left ventricular hypertrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Significance of myocardial alpha- and beta-adrenoceptors in catecholamine-induced cardiac hypertrophy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204275

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204275

1 reference

Dimensions Publication ID

31 July 2017

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1 reference