Podocyte injury caused by indoxyl sulfate, a uremic toxin and aryl-hydrocarbon receptor ligand (Q34227115)

31 July 2017

Podocyte injury caused by indoxyl sulfate, a uremic toxin and aryl-hydrocarbon receptor ligand (English)

1 reference

31 July 2017

Yasuhiro Kon

5

0 references

Teppei Nakamura

object named as

Teppei Nakamura

3

0 references

Avi Rosenberg

object named as

Avi Z Rosenberg

7

0 references

Jeffrey B. Kopp

object named as

Jeffrey B Kopp

8

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author name string

Osamu Ichii

1

1 reference

31 July 2017

Saori Otsuka-Kanazawa

2

1 reference

31 July 2017

Masaaki Ueno

4

1 reference

31 July 2017

Weiping Chen

6

1 reference

31 July 2017

language of work or name

English

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publication date

22 September 2014

1 reference

31 July 2017

1 reference

31 July 2017

9

1 reference

31 July 2017

e108448

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31 July 2017

9

1 reference

Creative Commons CC0 License

31 July 2017

start time

22 September 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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cites work

Indoxyl sulfate downregulates expression of Mas receptor via OAT3/AhR/Stat3 pathway in proximal tubular cells

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LPS and PAN-induced podocyte injury in an in vitro model of minimal change disease: changes in TLR profile

5 July 2018

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Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration.

5 July 2018

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Role of the podocyte (and glomerular endothelium) in building the GBM

5 July 2018

1 reference

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Signaling from the podocyte intercellular junction to the actin cytoskeleton

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

The aryl hydrocarbon receptor system

5 July 2018

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Normal and pathologic concentrations of uremic toxins

5 July 2018

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Podocyte-specific loss of Cdc42 leads to congenital nephropathy

5 July 2018

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Uremic toxins induce kidney fibrosis by activating intrarenal renin-angiotensin-aldosterone system associated epithelial-to-mesenchymal transition

5 July 2018

1 reference

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Indoxyl sulfate upregulates renal expression of MCP-1 via production of ROS and activation of NF-κB, p53, ERK, and JNK in proximal tubular cells

5 July 2018

1 reference

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Indoxyl sulfate-induced epithelial-to-mesenchymal transition and apoptosis of renal tubular cells as novel mechanisms of progression of renal disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Indoxyl sulfate induces nephrovascular senescence

5 July 2018

1 reference

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Indoxyl sulphate inhibits osteoclast differentiation and function

5 July 2018

1 reference

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Genomic damage in endstage renal disease-contribution of uremic toxins

5 July 2018

1 reference

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Cell biology and pathology of podocytes

5 July 2018

1 reference

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AHR regulates WT1 genetic programming during murine nephrogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Indoxyl sulfate downregulates renal expression of Klotho through production of ROS and activation of nuclear factor-ĸB.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Quantitative and qualitative urinary cellular patterns correlate with progression of murine glomerulonephritis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Indoxyl sulfate-induced endothelial dysfunction in patients with chronic kidney disease via an induction of oxidative stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Expression of aryl hydrocarbon receptor in human placentas and fetal tissues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

The mammalian aryl hydrocarbon (Ah) receptor: from mediator of dioxin toxicity toward physiological functions in skin and liver

5 July 2018

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Serum indoxyl sulfate is associated with vascular disease and mortality in chronic kidney disease patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

New insights into the role of podocytes in proteinuria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kappaB family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Tetracycline-inducible gene expression in conditionally immortalized mouse podocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Bmp in podocytes is essential for normal glomerular capillary formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Rho-family small GTPases are involved in forskolin-induced cell-cell contact formation of renal glomerular podocytes in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Intrarenal oxygenation in chronic renal failure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Molecular pathomechanisms of membranous nephropathy: from Heymann nephritis to alloimmunization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Review on uremic toxins: classification, concentration, and interindividual variability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

A new method for large scale isolation of kidney glomeruli from mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

An oral adsorbent ameliorates renal overload of indoxyl sulfate and progression of renal failure in diabetic rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Interleukin-1 beta and tumor necrosis factor-alpha induce gene expression and production of leukocyte chemotactic factors, colony-stimulating factors, and interleukin-6 in human mesangial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

Indoxyl sulfate induces complex redox alterations in mesangial cells

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0108448

New insight into the redox properties of uremic solute indoxyl sulfate as a pro- and anti-oxidant

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0108448

Indoxyl sulfate upregulates expression of ICAM-1 and MCP-1 by oxidative stress-induced NF-kappaB activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0108448

Critical role of cyclooxygenase-2 activation in pathogenesis of hydronephrosis caused by lactational exposure of mice to dioxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0108448

Tissue- and cell type-specific expression of cytochrome P450 1A1 and cytochrome P450 1A2 mRNA in the mouse localized in situ hybridization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0108448

Sodium octanoate to reverse indoxyl sulfate and p-cresyl sulfate albumin binding in uremic and normal serum during sample preparation followed by fluorescence liquid chromatography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0108448

Development of a biomarker assay for 3-indoxyl sulfate in mouse plasma and brain by liquid chromatography/tandem mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0108448

Effects of indoxyl sulfate on adherens junctions of endothelial cells and the underlying signaling mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0108448

Upregulation of nestin, vimentin, and desmin in rat podocytes in response to injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0108448

Aryl-hydrocarbon receptor-dependent alteration of FAK/RhoA in the inhibition of HUVEC motility by 3-methylcholanthrene

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0108448

Control of cell adhesion and migration by podocalyxin. Implication of Rac1 and Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0108448

Serine-71 phosphorylation of Rac1/Cdc42 diminishes the pathogenic effect of Clostridium difficile toxin A.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4171541

An oral sorbent reduces overload of indoxyl sulphate and gene expression of TGF-beta1 in uraemic rat kidneys

28 October 2018

1 reference

12 December 2020

Progression of glomerular sclerosis in experimental uremic rats by administration of indole, a precursor of indoxyl sulfate

1 reference

12 December 2020

HIV-1 genes vpr and nef synergistically damage podocytes, leading to glomerulosclerosis

1 reference

12 December 2020

Monoclonal anti-double-stranded DNA autoantibody stimulates the expression and release of IL-1beta, IL-6, IL-8, IL-10 and TNF-alpha from normal human mononuclear cells involving in the lupus pathogenesis

1 reference

12 December 2020

Beta 1 and beta 3 integrin upregulation in rapidly progressive glomerulonephritis

1 reference

12 December 2020

Podocytes loose their adhesive phenotype in focal segmental glomerulosclerosis

1 reference

12 December 2020

Effects of oral adsorbent AST-120 (Kremezin) on renal function and glomerular injury in early-stage renal failure of subtotal nephrectomized rats

1 reference

12 December 2020

Immunohistochemical determination of inducibility phenotype with a monoclonal antibody to a methylcholanthrene-inducible isozyme of cytochrome P-450

1 reference

12 December 2020

Indoxyl sulfate reduces klotho expression and promotes senescence in the kidneys of hypertensive rats

1 reference

12 December 2020

Indoxyl sulfate induces endothelial cell senescence by increasing reactive oxygen species production and p53 activity

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0108448

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DOI

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31 July 2017

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31 July 2017

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