Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses (Q34230044)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22052977%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses (English)

1 reference

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15 January 2020

main subject

reactive oxygen species

1 reference

0 references

1

1 reference

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15 January 2020

George Poulogiannis

2

1 reference

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15 January 2020

Jason W. Locasale

9

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15 January 2020

Craig J Thomas

11

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ORCID Public Data File 2021

author name string

John M Asara

3

1 reference

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15 January 2020

Matthew B Boxer

4

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15 January 2020

Jian-kang Jiang

5

1 reference

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15 January 2020

Min Shen

6

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15 January 2020

Gary Bellinger

7

1 reference

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15 January 2020

Atsuo T Sasaki

8

1 reference

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15 January 2020

Douglas S Auld

10

1 reference

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15 January 2020

Matthew G Vander Heiden

12

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15 January 2020

Lewis C Cantley

13

1 reference

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15 January 2020

language of work or name

English

0 references

publication date

3 November 2011

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15 January 2020

1 reference

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15 January 2020

volume

334

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15 January 2020

page(s)

1278-1283

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15 January 2020

issue

6060

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The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes

15 January 2020

cites work

1 reference

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6 July 2018

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Oxidative stress, inflammation, and cancer: how are they linked?

6 July 2018

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Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

6 July 2018

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Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

6 July 2018

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Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase

6 July 2018

1 reference

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Modulation of intracellular ROS levels by TIGAR controls autophagy

6 July 2018

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Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

6 July 2018

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

6 July 2018

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Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis

6 July 2018

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Redox-based regulation of signal transduction: principles, pitfalls, and promises

6 July 2018

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ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis

6 July 2018

1 reference

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471535

Pyruvate kinase M2 is a phosphotyrosine-binding protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471535

Redox proteomics identification of oxidatively modified brain proteins in Alzheimer's disease and mild cognitive impairment: insights into the progression of this dementing disorder.

6 July 2018

1 reference

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Oxidative stress and cancer: have we moved forward?

6 July 2018

1 reference

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The antioxidant function of the p53 tumor suppressor

6 July 2018

1 reference

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Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis

6 July 2018

1 reference

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Redox redux: revisiting PTPs and the control of cell signaling

6 July 2018

1 reference

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Protein disulfide bond formation in the cytoplasm during oxidative stress

6 July 2018

1 reference

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Failure to increase glucose consumption through the pentose-phosphate pathway results in the death of glucose-6-phosphate dehydrogenase gene-deleted mouse embryonic stem cells subjected to oxidative stress

6 July 2018

1 reference

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Metabolic control of resistance of human epithelial cells to H2O2 and NO stresses

6 July 2018

1 reference

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Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress

6 July 2018

1 reference

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Double role for pyruvate kinase type M2 in the expansion of phosphometabolite pools found in tumor cells.

6 July 2018

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Shotgun redox proteomics identifies specifically modified cysteines in key metabolic enzymes under oxidative stress in Saccharomyces cerevisiae.

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1211485

Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1211485

c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22052977

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The regulation of pyruvate kinase of Escherichia coli by fructose diphosphate and adenylic acid

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22052977

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1211485

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22052977%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22052977%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference