TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ(9)-tetrahydrocannabiorcol (Q34235326)

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17 January 2020

title

TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ(9)-tetrahydrocannabiorcol (English)

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17 January 2020

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17 January 2020

Stuart Bevan

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17 January 2020

Peter Zygmunt

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17 January 2020

author name string

Clive Gentry

2

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17 January 2020

Lisa Alenmyr

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17 January 2020

Dan Killander

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17 January 2020

Anders Andersson

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17 January 2020

Bernard Bucher

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17 January 2020

Jean-Luc Galzi

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17 January 2020

Olov Sterner

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17 January 2020

Edward D Högestätt

11

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17 January 2020

David A Andersson

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17 January 2020

publication date

22 November 2011

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17 January 2020

published in

Nature Communications

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17 January 2020

volume

2

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17 January 2020

page(s)

551

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https://scigraph.springernature.com/pub.10.1038/ncomms1559

17 January 2020

exact match

0 references

cites work

Pharmacokinetics/pharmacodynamics of acetaminophen analgesia in Japanese patients with chronic pain

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12 December 2020

Analgesic effect of acetaminophen in humans: first evidence of a central serotonergic mechanism

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12 December 2020

Transient receptor potential vanilloid type 1 activation down-regulates voltage-gated calcium channels through calcium-dependent calcineurin in sensory neurons

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12 December 2020

Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system

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12 December 2020

TRPA1-expressing primary afferents synapse with a morphologically identified subclass of substantia gelatinosa neurons in the adult rat spinal cord.

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12 December 2020

Mechanisms of acetaminophen-induced liver necrosis

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12 December 2020

Expression of transient receptor potential ankyrin 1 (TRPA1) in the rat trigeminal sensory afferents and spinal dorsal horn.

1 reference

12 December 2020

TRPV1 in brain is involved in acetaminophen-induced antinociception

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12 December 2020

Tropisetron inhibits the antinociceptive effect of intrathecally administered paracetamol and serotonin

1 reference

12 December 2020

Selective targeting of TRPV1 expressing sensory nerve terminals in the spinal cord for long lasting analgesia

1 reference

12 December 2020

Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents

1 reference

12 December 2020

Pungent products from garlic activate the sensory ion channel TRPA1

1 reference

12 December 2020

The antinociceptive action of paracetamol is associated with changes in the serotonergic system in the rat brain.

1 reference

12 December 2020

Roles of cutaneous versus spinal TRPA1 channels in mechanical hypersensitivity in the diabetic or mustard oil-treated non-diabetic rat.

1 reference

12 December 2020

Effects of microsomal enzyme induction on paracetamol metabolism in man

1 reference

12 December 2020

The involvement of the transient receptor potential A1 (TRPA1) in the maintenance of mechanical and cold hyperalgesia in persistent inflammation.

1 reference

12 December 2020

Chemosensory properties of the trigeminal system.

1 reference

12 December 2020

Unusual pungency from extra-virgin olive oil is attributable to restricted spatial expression of the receptor of oleocanthal

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12 December 2020

Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system

1 reference

12 December 2020

Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+.

1 reference

12 December 2020

Discovery of "self-synergistic" spinal/supraspinal antinociception produced by acetaminophen (paracetamol)

1 reference

12 December 2020

Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin

1 reference

12 December 2020

Capsaicin sensitivity and voltage-gated sodium currents in colon sensory neurons from rat dorsal root ganglia.

1 reference

12 December 2020

Acetaminophen blocks spinal hyperalgesia induced by NMDA and substance P

1 reference

12 December 2020

Activation characteristics of transient receptor potential ankyrin 1 and its role in nociception

1 reference

12 December 2020

Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder

1 reference

12 December 2020

Inhibition of Prostaglandin Synthetase in Brain explains the Anti-pyretic Activity of Paracetamol (4-Acetamidophenol)

1 reference

12 December 2020

Cytochrome P450 and associated monooxygenase activities in the rat and human spinal cord: induction, immunological characterization and immunocytochemical localization

1 reference

12 December 2020

Primary afferents with TRPM8 and TRPA1 profiles target distinct subpopulations of rat superficial dorsal horn neurones.

1 reference

12 December 2020

A spinal mechanism of action is involved in the antinociception produced by the capsaicin analogue NE 19550 (olvanil)

1 reference

12 December 2020

Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and Cyp2e1-null mice

1 reference

12 December 2020

Isobolographic analysis of the antinociceptive interactions of clonidine with nonsteroidal anti-inflammatory drugs

1 reference

12 December 2020

Antinociceptive profiles of aspirin and acetaminophen in formalin, substance P and glutamate pain models

1 reference

12 December 2020

Prostanoids synthesized by cyclo-oxygenase isoforms in rat spinal cord and their contribution to the development of neuronal hyperexcitability

1 reference

12 December 2020

Capsaicin indirectly suppresses voltage-gated Na+ currents through TRPV1 in rat dorsal root ganglion neurons

1 reference

12 December 2020

Capsaicin causes prolonged inhibition of voltage-activated calcium currents in adult rat dorsal root ganglion neurons in culture

1 reference

12 December 2020

Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents

1 reference

12 December 2020

N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen

1 reference

12 December 2020

The 1- and 2-electron oxidation of acetaminophen catalyzed by prostaglandin H synthase

1 reference

12 December 2020

Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain

1 reference

12 December 2020

Capsaicin inhibits activation of voltage-gated sodium currents in capsaicin-sensitive trigeminal ganglion neurons

1 reference

12 December 2020

Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1

1 reference

12 December 2020

Activation of TRPA1 channel facilitates excitatory synaptic transmission in substantia gelatinosa neurons of the adult rat spinal cord.

1 reference

12 December 2020

TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents

1 reference

12 December 2020

Spinal transient receptor potential ankyrin 1 channel contributes to central pain hypersensitivity in various pathophysiological conditions in the rat.

1 reference

12 December 2020

Epidural capsaicin produces prolonged segmental analgesia in the rat.

1 reference

12 December 2020

Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs

1 reference

12 December 2020

ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures

1 reference

12 December 2020

TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction

1 reference

12 December 2020

Identification of S-(2,5-dihydroxyphenyl)-cysteine and S-(2,5-dihydroxyphenyl)-N-acetyl-cysteine as urinary metabolites of acetaminophen in the mouse. Evidence for p-benzoquinone as a reactive intermediate in acetaminophen metabolism

1 reference

12 December 2020

Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat

1 reference

12 December 2020

Mouse K-Cl cotransporter KCC1: cloning, mapping, pathological expression, and functional regulation

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS1559

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCOMMS1559

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22109525%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

17 January 2020

ADS bibcode

2011NatCo...2..551A

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