PEARL-HF: prevention of hyperkalemia in patients with heart failure using a novel polymeric potassium binder, RLY5016. (Q34241836)

31 July 2017

PEARL-HF: prevention of hyperkalemia in patients with heart failure using a novel polymeric potassium binder, RLY5016. (English)

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31 July 2017

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3

Bertram Pitt

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31 July 2017

Jerry M Buysse

1

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PubMed ID

22185443

31 July 2017

I-Zu Huang

series ordinal

2

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31 July 2017

1 January 2012

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31 July 2017

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31 July 2017

8

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31 July 2017

1

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31 July 2017

17-28

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The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators

31 July 2017

1 reference

Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction

21 January 2018

1 reference

Eplerenone in patients with systolic heart failure and mild symptoms

21 January 2018

1 reference

Aldosterone blockade and left ventricular dysfunction: a systematic review of randomized clinical trials.

21 January 2018

1 reference

Managing hyperkalemia caused by inhibitors of the renin-angiotensin-aldosterone system

21 January 2018

1 reference

Mechanisms of impaired potassium handling with dual renin-angiotensin-aldosterone blockade in chronic kidney disease

21 January 2018

1 reference

The risks and benefits of therapy with aldosterone receptor antagonist therapy

21 January 2018

1 reference

Pharmacokinetics and pharmacodynamics of mineralocorticoid blocking agents and their effects on potassium homeostasis

21 January 2018

1 reference

Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study

21 January 2018

1 reference

Evaluation of the efficacy and safety of RLY5016, a polymeric potassium binder, in a double-blind, placebo-controlled study in patients with chronic heart failure (the PEARL-HF) trial

21 January 2018

1 reference

Potassium homeostasis and clinical implications

21 January 2018

1 reference

Apical potassium (BK) channels and enhanced potassium secretion in human colon

21 January 2018

1 reference

Colonic potassium handling.

21 January 2018

1 reference

Enhanced large intestinal potassium permeability in end-stage renal disease

21 January 2018

1 reference

Aldosterone increases KCa1.1 (BK) channel-mediated colonic K+ secretion

21 January 2018

1 reference

Dietary potassium and laxatives as regulators of colonic potassium secretion in end-stage renal disease

21 January 2018

1 reference

The use of sodium polystyrene sulfonate in the inpatient management of hyperkalemia

21 January 2018

1 reference

Serum potassium and clinical outcomes in the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS).

21 January 2018

1 reference

Hyperkalemia in patients with heart failure: incidence, prevalence, and management

21 January 2018

1 reference

Managing chronic heart failure patient in chronic kidney disease.

21 January 2018

1 reference

The frequency of hyperkalemia and its significance in chronic kidney disease.

21 January 2018

1 reference

Predictors of hyperkalemia risk following hypertension control with aldosterone blockade

21 January 2018

1 reference

Understanding the risk of hyperkalaemia in heart failure: role of aldosterone antagonism

21 January 2018

1 reference

Association of aldosterone concentration and mineralocorticoid receptor genotype with potassium response to spironolactone in patients with heart failure

21 January 2018

1 reference

Ion-exchange resins for the treatment of hyperkalemia: are they safe and effective?

21 January 2018

1 reference

Supratherapeutic doses of angiotensin receptor blockers to decrease proteinuria in patients with chronic kidney disease

21 January 2018

1 reference

Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)

21 January 2018

1 reference

Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARM-Alternative trial

21 January 2018

1 reference

Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure

21 January 2018

1 reference

Hypokalemia and outcomes in patients with chronic heart failure and chronic kidney disease: findings from propensity-matched studies

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/FCA.11.71

1 reference

31 July 2017

1 reference

PubMed ID

22185443