Vaccination against trypanosomiasis: can it be done or is the trypanosome truly the ultimate immune destroyer and escape artist? (Q34243439)

31 July 2017

4 references

23 March 2019

20 June 2019

22 October 2019

28 May 2020

Vaccination against trypanosomiasis: can it be done or is the trypanosome truly the ultimate immune destroyer and escape artist? (English)

1 reference

31 July 2017

0 references

African trypanosomiasis

4 references

23 March 2019

20 June 2019

22 October 2019

28 May 2020

1 reference

22 October 2019

Stefan Magez

2

0 references

author name string

Florencia La Greca

series ordinal

1

1 reference

31 July 2017

language of work or name

1 reference

1 November 2011

5 references

31 July 2017

23 March 2019

20 June 2019

22 October 2019

28 May 2020

5 references

31 July 2017

23 March 2019

20 June 2019

22 October 2019

28 May 2020

7

1 reference

31 July 2017

issue

11

1 reference

31 July 2017

page(s)

1225-1233

1 reference

Creative Commons Attribution-NonCommercial 3.0 Unported

31 July 2017

copyright license

4 references

23 March 2019

20 June 2019

22 October 2019

on focus list of Wikimedia project

28 May 2020

ScienceSource

0 references

cites work

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Trypanosoma brucei: immunisation with plasmid DNA encoding invariant surface glycoprotein gene is able to induce partial protection in experimental African trypanosomiasis.

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A major genetic locus in Trypanosoma brucei is a determinant of host pathology

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Immunolocalization and challenge studies using a recombinant Vibrio cholerae ghost expressing Trypanosoma brucei Ca(2+) ATPase (TBCA2) antigen

6 July 2018

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6 July 2018

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Trypanosoma brucei rhodesiense transmitted by a single tsetse fly bite in vervet monkeys as a model of human African trypanosomiasis

6 July 2018

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Contributions of experimental mouse models to the understanding of African trypanosomiasis

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Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responses

6 July 2018

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Alternatively activated myeloid cells limit pathogenicity associated with African trypanosomiasis through the IL-10 inducible gene selenoprotein P.

6 July 2018

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Sleeping sickness in West Africa (1906-2006): changes in spatial repartition and lessons from the past.

6 July 2018

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Spatially and genetically distinct African Trypanosome virulence variants defined by host interferon-gamma response

6 July 2018

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Immunization with recombinant beta-tubulin from Trypanosoma evansi induced protection against T. evansi, T. equiperdum and T. b. brucei infection in mice.

6 July 2018

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The two faces of interleukin 10 in human infectious diseases

6 July 2018

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The Genome of the African Trypanosome Trypanosoma brucei

6 July 2018

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Trypanosomes expressing a mosaic variant surface glycoprotein coat escape early detection by the immune system

6 July 2018

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Severity of human african trypanosomiasis in East Africa is associated with geographic location, parasite genotype, and host inflammatory cytokine response profile

6 July 2018

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6 July 2018

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Endotoxins and their significance for murine trypanosomiasis

6 July 2018

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6 July 2018

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Immunization with a tubulin-rich preparation from Trypanosoma brucei confers broad protection against African trypanosomosis

6 July 2018

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6 July 2018

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Immunisation of cattle with cysteine proteinases of Trypanosoma congolense: targetting the disease rather than the parasite

6 July 2018

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An update on antigenic variation in African trypanosomes

6 July 2018

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Antibodies raised against the flagellar pocket fraction of Trypanosoma brucei preferentially recognize HSP60 in cDNA expression library

6 July 2018

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6 July 2018

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Tumor necrosis factor alpha is a key mediator in the regulation of experimental Trypanosoma brucei infections

6 July 2018

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Characterization of a novel trypanosome lytic factor from human serum

6 July 2018

1 reference

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A VSG expression site-associated gene confers resistance to human serum in Trypanosoma rhodesiense

6 July 2018

1 reference

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Trypanosoma evansi and T. equiperdum: distribution, biology, treatment and phylogenetic relationship (a review).

6 July 2018

1 reference

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The glycosyl-inositol-phosphate and dimyristoylglycerol moieties of the glycosylphosphatidylinositol anchor of the trypanosome variant-specific surface glycoprotein are distinct macrophage-activating factors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323498

Specific uptake of tumor necrosis factor-alpha is involved in growth control of Trypanosoma brucei.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323498

The identification, purification, and characterization of two invariant surface glycoproteins located beneath the surface coat barrier of bloodstream forms of Trypanosoma brucei.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323498

Organization of two invariant surface glycoproteins in the surface coat of Trypanosoma brucei.

6 July 2018

1 reference

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ESAG 6 and 7 products of Trypanosoma brucei form a transferrin binding protein complex.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323498

Murine tumour necrosis factor plays a protective role during the initial phase of the experimental infection with Trypanosoma brucei brucei.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323498

The serum resistance-associated (SRA) gene of Trypanosoma brucei rhodesiense encodes a variant surface glycoprotein-like protein

6 July 2018

1 reference

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Correlation of high serum levels of tumor necrosis factor-alpha with disease severity in human African trypanosomiasis

6 July 2018

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Response of the murine lymphoid system to a chronic infection with Trypanosoma congolense. I. The spleen

6 July 2018

1 reference

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Host susceptibility to African trypanosomiasis: trypanotolerance

6 July 2018

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The pathology of African Trypanosomiasis

6 July 2018

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Protein catabolism in trypanosomiasis

6 July 2018

1 reference

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Human “healthy carriers” of Trypanosoma (brucei type) discovered by immunofluorescence test in the Republique Democratique Du Congo

6 July 2018

1 reference

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Immunoglobulin M production and immunosuppression in trypanosomiasis: a linking hypothesis

6 July 2018

1 reference

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Characteristics of trypanosome variant antigen genes active in the tsetse fly.

6 July 2018

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Subpellicular and flagellar microtubules of Trypanosoma brucei brucei contain the same alpha-tubulin isoforms

6 July 2018

1 reference

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Complex events in the evolution of the haptoglobin gene cluster in primates

6 July 2018

1 reference

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A new method for the isolation of the trypanocidal factor from normal human serum

6 July 2018

1 reference

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A novel cell surface trans-sialidase of trypanosoma cruzi generates a stage-specific epitope required for invasion of mammalian cells

6 July 2018

1 reference

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Transmission of South American Trypanosoma vivax by the neotropical horsefly Tabanus nebulosus

6 July 2018

1 reference

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Identification of invariant surface glycoproteins in the bloodstream stage of Trypanosoma brucei.

6 July 2018

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6 July 2018

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The epidemiology of sleeping sickness in the historical Luangwa valley

6 July 2018

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Mechanical transmission of Trypanosoma congolense in cattle by the African tabanid Atylotus agrestis

6 July 2018

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Mechanical transmission of Trypanosoma vivax in cattle by the African tabanid Atylotus fuscipes

21 January 2018

1 reference

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Responses of bovine chimaeras combining trypanosomosis resistant and susceptible genotypes to experimental infection with Trypanosoma congolense

21 January 2018

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Characterization of Trypanosoma brucei s.l. infecting asymptomatic sleeping-sickness patients in Côte d'Ivoire: a new genetic group?

21 January 2018

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Trypanosoma brucei ssp. and T congolense: mixed human infection in Côte d'Ivoire

21 January 2018

1 reference

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Immunization with recombinant actin from Trypanosoma evansi induces protective immunity against T. evansi, T. equiperdum and T. b. brucei infection

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.18203

Tumour necrosis factor production by monocytes from cattle infected with Trypanosoma (Duttonella) vivax and Trypanosoma (Nannomonas) congolense: possible association with severity of anaemia associated with the disease

21 January 2018

1 reference

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Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria

21 January 2018

1 reference

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Antibody responses to a 33 kDa cysteine protease of Trypanosoma congolense: relationship to 'trypanotolerance' in cattle

21 January 2018

1 reference

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Functional expression of the catalytic domains of two cysteine proteinases from Trypanosoma congolense

21 January 2018

1 reference

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Susceptibility of tumour necrosis factor-alpha genetically deficient mice to Trypanosoma congolense infection

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.18203

Experimental African trypanosomiasis: a subset of pathogenic, IFN-gamma-producing, MHC class II-restricted CD4+ T cells mediates early mortality in highly susceptible mice

21 January 2018

1 reference

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Relative contribution of interferon-gamma and interleukin-10 to resistance to murine African trypanosomosis.

21 January 2018

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VSG-GPI anchors of African trypanosomes: their role in macrophage activation and induction of infection-associated immunopathology

21 January 2018

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The vervet monkey (Chlorocebus aethiops) as an experimental model for Trypanosoma brucei gambiense human African trypanosomiasis: a clinical, biological and pathological study.

21 January 2018

1 reference

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Partial protection against natural trypanosomiasis after vaccination with a flagellar pocket antigen from Trypanosoma brucei rhodesiense

21 January 2018

1 reference

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Trypanosoma brucei rhodesiense infection in vervet monkeys. II. Provocation of the encephalitic late phase by treatment of infected monkeys.

28 October 2018

1 reference

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Tumor Necrosis Factor (TNF) Receptor–1 (TNFp55) Signal Transduction and Macrophage‐Derived Soluble TNF Are Crucial for Nitric Oxide–MediatedTrypanosoma congolenseParasite Killing

28 October 2018

3 references

https://api.crossref.org/works/10.4161%2FHV.7.11.18203

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323498

9 December 2018

12 December 2020

A Glycosylphosphatidylinositol-Based Treatment Alleviates Trypanosomiasis-Associated Immunopathology

3 references

https://api.crossref.org/works/10.4161%2FHV.7.11.18203

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323498

9 December 2018

12 December 2020

Interferon‐γ and Nitric Oxide in Combination with Antibodies Are Key Protective Host Immune Factors duringTrypanosoma congolenseTc13 Infections

3 references

https://api.crossref.org/works/10.4161%2FHV.7.11.18203

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323498

9 December 2018

12 December 2020

Tumour necrosis factor as immunomodulator and mediator of monocyte cytotoxicity induced by itself, γ-interferon and interleukin-1

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.18203

Localization of genes controlling resistance to trypanosomiasis in mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323498

Immunosuppression in Trypanosoma brucei infections in rats and mice

9 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323498

The nature of immunosuppression in Trypanosoma brucei infections in mice. II. The role of the T and B lymphocytes

9 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323498

Purification and characterization of a novel glycan-phosphatidylinositol-specific phospholipase C from Trypanosoma brucei

9 December 2018

1 reference

PubMed

12 December 2020

Simultaneous but independent activation of adenylate cyclase and glycosylphosphatidylinositol-phospholipase C under stress conditions in Trypanosoma brucei

1 reference

PubMed

12 December 2020

Identifiers

DOI

10.4161/HV.7.11.18203

1 reference

31 July 2017

1 reference

31 July 2017

1 reference