Androgen-regulated miR-32 targets BTG2 and is overexpressed in castration-resistant prostate cancer (Q34248844)

31 July 2017

Androgen-regulated miR-32 targets BTG2 and is overexpressed in castration-resistant prostate cancer (English)

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31 July 2017

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S E Jalava

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A Urbanucci

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L Latonen

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31 July 2017

K K Waltering

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B Sahu

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O A Jänne

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J Seppälä

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H Lähdesmäki

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T L J Tammela

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T Visakorpi

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31 July 2017

language of work or name

English

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publication date

23 January 2012

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31 July 2017

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31

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41

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31 July 2017

4460-4471

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https://scigraph.springernature.com/pub.10.1038/onc.2011.624

31 July 2017

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Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven.

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Reactivation of androgen receptor-regulated TMPRSS2:ERG gene expression in castration-resistant prostate cancer

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The development of androgen-independent prostate cancer

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Antiproliferative B cell translocation gene 2 protein is down-regulated post-transcriptionally as an early event in prostate carcinogenesis

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Most mammalian mRNAs are conserved targets of microRNAs

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MiR-148a attenuates paclitaxel resistance of hormone-refractory, drug-resistant prostate cancer PC3 cells by regulating MSK1 expression

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Mammalian microRNAs predominantly act to decrease target mRNA levels

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Phosphorylation of serine 147 of tis21/BTG2/pc3 by p-Erk1/2 induces Pin-1 binding in cytoplasm and cell death

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BTG2 is an LXXLL-dependent co-repressor for androgen receptor transcriptional activity

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TCEB1 promotes invasion of prostate cancer cells

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MicroRNA expression profiles classify human cancers

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Diagnostic and prognostic signatures from the small non-coding RNA transcriptome in prostate cancer

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Targeting continued androgen receptor signaling in prostate cancer

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Up-regulation of cell cycle arrest protein BTG2 correlates with increased overall survival in breast cancer, as detected by immunohistochemistry using tissue microarray

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miR-148a is an androgen-responsive microRNA that promotes LNCaP prostate cell growth by repressing its target CAND1 expression

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miR-21: an androgen receptor-regulated microRNA that promotes hormone-dependent and hormone-independent prostate cancer growth

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Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer

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Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites

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TMPRSS2:ERG fusion identifies a subgroup of prostate cancers with a favorable prognosis.

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Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis

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Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer

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The role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines

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Increased expression of androgen receptor sensitizes prostate cancer cells to low levels of androgens.

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Androgen regulation of micro-RNAs in prostate cancer

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The mammalian anti-proliferative BTG/Tob protein family

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Model-based analysis of ChIP-Seq (MACS)

21 January 2018

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PI3K is negatively regulated by PIK3IP1, a novel p110 interacting protein

21 January 2018

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Interaction of androgen receptors with androgen response element in intact cells. Roles of amino- and carboxyl-terminal regions and the ligand

21 January 2018

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Association of SPINK1 expression and TMPRSS2:ERG fusion with prognosis in endocrine-treated prostate cancer

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2011.624

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Dimensions Publication ID

31 July 2017

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