Comparative study of four immortalized human brain capillary endothelial cell lines, hCMEC/D3, hBMEC, TY10, and BB19, and optimization of culture conditions, for an in vitro blood-brain barrier model for drug permeability studies (Q34250155)

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English	Comparative study of four immortalized human brain capillary endothelial cell lines, hCMEC/D3, hBMEC, TY10, and BB19, and optimization of culture conditions, for an in vitro blood-brain barrier model for drug permeability studies	scientific article

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scholarly article

1 reference

Europe PubMed Central

31 July 2017

Comparative study of four immortalized human brain capillary endothelial cell lines, hCMEC/D3, hBMEC, TY10, and BB19, and optimization of culture conditions, for an in vitro blood-brain barrier model for drug permeability studies (English)

1 reference

Europe PubMed Central

31 July 2017

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blood–brain barrier

1 reference

based on heuristic

inferred from title

object named as

Mouhssin Oufir

6

0 references

Matthias Hamburger

5

object named as

Matthias Hamburger

1 reference

Europe PubMed Central

31 July 2017

author name string

Daniela E Eigenmann

1

1 reference

Europe PubMed Central

31 July 2017

Gongda Xue

2

1 reference

Europe PubMed Central

31 July 2017

Kwang S Kim

3

1 reference

Europe PubMed Central

31 July 2017

Ashlee V Moses

4

1 reference

Europe PubMed Central

31 July 2017

publication date

22 November 2013

1 reference

Europe PubMed Central

31 July 2017

Fluids and Barriers of the CNS

1 reference

Europe PubMed Central

31 July 2017

10

1 reference

Europe PubMed Central

31 July 2017

33

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Europe PubMed Central

31 July 2017

1

1 reference

Europe PubMed Central

31 July 2017

https://scigraph.springernature.com/pub.10.1186/2045-8118-10-33

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GABAA receptor modulation by piperine and a non-TRPV1 activating derivative

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The hCMEC/D3 cell line as a model of the human blood brain barrier

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Impedance-based cell monitoring: barrier properties and beyond

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Membrane configuration optimization for a murine in vitro blood-brain barrier model

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Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood-brain barrier penetration models

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Time-dependent dual effects of high levels of unconjugated bilirubin on the human blood-brain barrier lining

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In vitro blood-brain barrier models: current and perspective technologies

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Hepatitis C virus infects the endothelial cells of the blood-brain barrier

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In vitro modeling of the blood-brain barrier: simplicity versus complexity

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Development of a three-dimensional, all-human in vitro model of the blood-brain barrier using mono-, co-, and tri-cultivation Transwell models

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Peripheral nerve pericytes modify the blood-nerve barrier function and tight junctional molecules through the secretion of various soluble factors

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Establishment of a new conditionally immortalized human brain microvascular endothelial cell line retaining an in vivo blood-brain barrier function

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Neisseria meningitidis induces brain microvascular endothelial cell detachment from the matrix and cleavage of occludin: a role for MMP-8.

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6 July 2018

The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies

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Comparison of blood-brain barrier permeability assays: in situ brain perfusion, MDR1-MDCKII and PAMPA-BBB.

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VE-cadherin and claudin-5: it takes two to tango.

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Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier

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Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers

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Modelling of the blood-brain barrier in drug discovery and development.

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Immortalized human brain endothelial cells and flow-based vascular modeling: a marriage of convenience for rational neurovascular studies

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Methods to assess drug permeability across the blood-brain barrier

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6 July 2018

Astrocyte-endothelial interactions at the blood-brain barrier

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6 July 2018

Evaluation of the immortalized human brain capillary endothelial cell line BB19 as a human cell culture model for the blood-brain barrier

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6 July 2018

Blood-brain barrier-specific properties of a human adult brain endothelial cell line

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6 July 2018

Establishment of an in vitro brain barrier epithelial transport system for pharmacological and toxicological study

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6 July 2018

Permeability studies on in vitro blood-brain barrier models: physiology, pathology, and pharmacology.

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How to measure drug transport across the blood-brain barrier

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The blood-brain barrier: bottleneck in brain drug development

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African trypanosome interactions with an in vitro model of the human blood-brain barrier

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In vitro trans-monolayer permeability calculations: often forgotten assumptions

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An overview of in vitro techniques for blood-brain barrier studies

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6 July 2018

Relationship between permeability status of the blood-brain barrier and in vitro permeability coefficient of a drug

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In vitro model for evaluating drug transport across the blood-brain barrier

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Studies of Plasmodium falciparum cytoadherence using immortalized human brain capillary endothelial cells

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A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes

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The use of in vitro cell culture models for mechanistic studies and as permeability screens for the blood-brain barrier in the pharmaceutical industry--background and current status in the drug discovery process.

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An in vitro blood-brain barrier model for high throughput (HTS) toxicological screening.

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Serum-derived factors weaken the barrier properties of cultured porcine brain capillary endothelial cells in vitro

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Atorvastatin partially prevents an inflammatory barrier breakdown of cultured human brain endothelial cells at a pharmacologically relevant concentration.

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Demystifying brain penetration in central nervous system drug discovery. Miniperspective

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Human astrocytes/astrocyte-conditioned medium and shear stress enhance the barrier properties of human brain microvascular endothelial cells

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Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors

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Prediction of blood-brain barrier permeation in drug discovery from in vivo, in vitro and in silico models

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https://pubmed.ncbi.nlm.nih.gov/24262108

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10.1186/2045-8118-10-33

1 reference

Europe PubMed Central

31 July 2017

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1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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