Oligomeric amyloid-{beta} inhibits the proteolytic conversion of brain-derived neurotrophic factor (BDNF), AMPA receptor trafficking, and classical conditioning (Q34251263)

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English	Oligomeric amyloid-{beta} inhibits the proteolytic conversion of brain-derived neurotrophic factor (BDNF), AMPA receptor trafficking, and classical conditioning	scientific article

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13 February 2020

Oligomeric amyloid-{beta} inhibits the proteolytic conversion of brain-derived neurotrophic factor (BDNF), AMPA receptor trafficking, and classical conditioning (English)

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13 February 2020

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13 February 2020

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Zhaoqing Zheng

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13 February 2020

Boris Sabirzhanov

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13 February 2020

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31 August 2010

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13 February 2020

Journal of Biological Chemistry

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13 February 2020

285

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13 February 2020

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13 February 2020

34708-34717

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13 February 2020

Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process

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6 July 2018

Cleavage of proBDNF to BDNF by a tolloid-like metalloproteinase is required for acquisition of in vitro eyeblink classical conditioning

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6 July 2018

Alzheimer's disease: synaptic dysfunction and Abeta

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6 July 2018

PKA has a critical role in synaptic delivery of GluR1- and GluR4-containing AMPARs during initial stages of acquisition of in vitro classical conditioning

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6 July 2018

{beta}-Amyloid impairs AMPA receptor trafficking and function by reducing Ca2+/calmodulin-dependent protein kinase II synaptic distribution

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6 July 2018

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

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6 July 2018

BDNF-induced synaptic delivery of AMPAR subunits is differentially dependent on NMDA receptors and requires ERK.

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6 July 2018

Protein kinase C-dependent and independent signaling pathways regulate synaptic GluR1 and GluR4 AMPAR subunits during in vitro classical conditioning

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6 July 2018

New insights into brain BDNF function in normal aging and Alzheimer disease

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6 July 2018

Coordinate action of pre- and postsynaptic brain-derived neurotrophic factor is required for AMPAR trafficking and acquisition of in vitro classical conditioning

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6 July 2018

Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human neuroblastoma cells

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6 July 2018

AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss

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6 July 2018

Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ

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6 July 2018

Quantitative analysis of immunofluorescent punctate staining of synaptically localized proteins using confocal microscopy and stereology

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6 July 2018

AMPA receptor downscaling at the onset of Alzheimer's disease pathology in double knockin mice.

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6 July 2018

Characterization of polysaccharides from the flowers of Nerium indicum and their neuroprotective effects.

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6 July 2018

MAPK recruitment by beta-amyloid in organotypic hippocampal slice cultures depends on physical state and exposure time

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6 July 2018

Brain-derived neurotrophic factor-dependent unmasking of "silent" synapses in the developing mouse barrel cortex

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6 July 2018

Properties of conditioned abducens nerve responses in a highly reduced in vitro brain stem preparation from the turtle.

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6 July 2018

Brain-derived neurotrophic factor is reduced in Alzheimer's disease.

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6 July 2018

Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses

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21 January 2018

Brain-derived neurotrophic factor regulates the expression and synaptic delivery of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits in hippocampal neurons.

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21 January 2018

Brain-derived neurotrophic factor regulates AMPA receptor trafficking to post-synaptic densities via IP3R and TRPC calcium signaling

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21 January 2018

Quantitation of BDNF mRNA in human parietal cortex by competitive reverse transcription-polymerase chain reaction: decreased levels in Alzheimer's disease.

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21 January 2018

Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease.

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21 January 2018

BDNF is a novel marker of cognitive function in ageing women: the DR's EXTRA Study.

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21 January 2018

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

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21 January 2018

ApoE isoform-specific effects on LTP: blockade by oligomeric amyloid-beta1-42.

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21 January 2018

Conversion of silent synapses into the active pool by selective GluR1-3 and GluR4 AMPAR trafficking during in vitro classical conditioning.

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21 January 2018

Evidence that caspase-1 is a negative regulator of AMPA receptor-mediated long-term potentiation at hippocampal synapses.

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Activation of the c-Jun N-terminal kinase signaling cascade mediates the effect of amyloid-beta on long term potentiation and cell death in hippocampus: a role for interleukin-1beta?

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21 January 2018

Amyloid beta prevents activation of calcium/calmodulin-dependent protein kinase II and AMPA receptor phosphorylation during hippocampal long-term potentiation

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21 January 2018

Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway.

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21 January 2018

ERK1/2 activation mediates Abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures.

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21 January 2018

Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters

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21 January 2018

In vitro eye-blink classical conditioning is NMDA receptor dependent and involves redistribution of AMPA receptor subunit GluR4.

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13 February 2020

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13 February 2020

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