Evolutionary meta-analysis of association studies reveals ancient constraints affecting disease marker discovery (Q34258585)

31 July 2017

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Evolutionary meta-analysis of association studies reveals ancient constraints affecting disease marker discovery (English)

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31 July 2017

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Sudhir Kumar

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Atul Butte

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4

object named as

Atul J Butte

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31 July 2017

Joel T Dudley

1

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31 July 2017

Rong Chen

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2

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31 July 2017

Maxwell Sanderford

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3

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31 July 2017

publication date

1 March 2012

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Molecular Biology and Evolution

31 July 2017

published in

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31 July 2017

volume

29

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31 July 2017

issue

9

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31 July 2017

page(s)

2087-2094

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Phylomedicine: an evolutionary telescope to explore and diagnose the universe of disease mutations

31 July 2017

cites work

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Non-synonymous and synonymous coding SNPs show similar likelihood and effect size of human disease association

6 July 2018

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Integrating common and rare genetic variation in diverse human populations

6 July 2018

1 reference

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Genomewide association studies and assessment of the risk of disease

6 July 2018

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Estimation of effect size distribution from genome-wide association studies and implications for future discoveries

6 July 2018

1 reference

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An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus

6 July 2018

1 reference

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Missing heritability and strategies for finding the underlying causes of complex disease

6 July 2018

1 reference

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Clinical assessment incorporating a personal genome

6 July 2018

1 reference

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Genetic heterogeneity in human disease

6 July 2018

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6 July 2018

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Rare variants create synthetic genome-wide associations

6 July 2018

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From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes.

6 July 2018

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Finding the missing heritability of complex diseases

6 July 2018

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Positional conservation and amino acids shape the correct diagnosis and population frequencies of benign and damaging personal amino acid mutations

6 July 2018

1 reference

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Common genetic variation and human traits

6 July 2018

1 reference

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Natural selection on genes that underlie human disease susceptibility

6 July 2018

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Common and rare variants in multifactorial susceptibility to common diseases

6 July 2018

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The molecular genetics of type 1 diabetes: new genes and emerging mechanisms

6 July 2018

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Natural selection has driven population differentiation in modern humans

6 July 2018

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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

6 July 2018

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Replicating genotype-phenotype associations

6 July 2018

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TimeTree: a public knowledge-base of divergence times among organisms

6 July 2018

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6 July 2018

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Coding single-nucleotide polymorphisms associated with complex vs. Mendelian disease: evolutionary evidence for differences in molecular effects.

6 July 2018

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6 July 2018

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6 July 2018

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Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance--a population-based twin study.

6 July 2018

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Crohn's disease: the genetic contribution

6 July 2018

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Genetics of human hypertension

6 July 2018

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Familial resemblance for coronary heart disease risk: the HERITAGE Family Study.

28 October 2018

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Fine mapping of the MHC Class III region demonstrates association of AIF1 and rheumatoid arthritis

28 October 2018

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28 October 2018

Identifiers

DOI

10.1093/MOLBEV/MSS079

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31 July 2017

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31 July 2017

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