Tetrodotoxin (TTX) as a therapeutic agent for pain. (Q34260913)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412801%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

2 references

3 November 2020

1 May 2021

Tetrodotoxin (TTX) as a therapeutic agent for pain (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412801%20AND%20SRC:MED&resulttype=core&format=json

voltage-gated sodium channel

25 January 2020

main subject

heterocyclic compound

1 reference

17 September 2019

1 reference

2 October 2019

1 reference

28 November 2019

1 reference

15 December 2019

1 reference

ChEBI release 2020-05-28

ChEBI ID

9506

1 reference

3 November 2020

sodium channel blocker

1 reference

1 May 2021

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412801%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Francisco Rafael Nieto

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412801%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Enrique José Cobos

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412801%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Miguel Ángel Tejada

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412801%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Cristina Sánchez-Fernández

4

1 reference

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25 January 2020

Cruz Miguel Cendán

6

1 reference

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25 January 2020

publication date

31 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412801%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 February 2012

2 references

3 November 2020

1 May 2021

7 references

17 September 2019

2 October 2019

28 November 2019

15 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412801%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

3 November 2020

1 May 2021

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412801%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412801%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

page(s)

281-305

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412801%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

25 January 2020

copyright license

6 references

17 September 2019

2 October 2019

28 November 2019

15 December 2019

3 November 2020

Regulatory Role of Voltage-Gated Na Channel β Subunits in Sensory Neurons

1 May 2021

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Clinical spectrum of SCN2A mutations.

6 July 2018

1 reference

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Sodium channels and microglial function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Pain as a global public health priority

6 July 2018

1 reference

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Identification of sodium channel isoforms that mediate action potential firing in lamina I/II spinal cord neurons.

6 July 2018

1 reference

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The roles of sodium channels in nociception: implications for mechanisms of neuropathic pain

6 July 2018

1 reference

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Increased expression of sodium channel subunit Nav1.1 in the injured dorsal root ganglion after peripheral nerve injury

6 July 2018

1 reference

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Intrathecal lidocaine pretreatment attenuates immediate neuropathic pain by modulating Nav1.3 expression and decreasing spinal microglial activation

6 July 2018

1 reference

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A multicentre open-label safety and efficacy study of tetrodotoxin for cancer pain

6 July 2018

1 reference

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Neuropathic Nav1.3-mediated sensitization to P2X activation is regulated by protein kinase C

6 July 2018

1 reference

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Sodium-calcium exchanger and multiple sodium channel isoforms in intra-epidermal nerve terminals.

6 July 2018

1 reference

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What is this thing called pain?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

The tetrodotoxin binding site is within the outer vestibule of the sodium channel

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Sodium channels in normal and pathological pain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Bidirectional modulation of isoflurane potency by intrathecal tetrodotoxin and veratridine in rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Cardiac sodium channelopathies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Voltage-gated sodium channels: therapeutic targets for pain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Sodium channel blockers for the treatment of neuropathic pain

6 July 2018

1 reference

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Neuropathic pain: a maladaptive response of the nervous system to damage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Increased peripheral nerve excitability and local NaV1.8 mRNA up-regulation in painful neuropathy.

6 July 2018

1 reference

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Early blockade of injured primary sensory afferents reduces glial cell activation in two rat neuropathic pain models

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Interaction between voltage-gated sodium channels and the neurotoxin, tetrodotoxin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Tetrodotoxin: a brief history

6 July 2018

1 reference

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Localization and targeting of voltage-dependent ion channels in mammalian central neurons.

6 July 2018

1 reference

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Proteomic profiling of neuromas reveals alterations in protein composition and local protein synthesis in hyper-excitable nerves

6 July 2018

1 reference

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Comparative study of the distribution of the alpha-subunits of voltage-gated sodium channels in normal and axotomized rat dorsal root ganglion neurons

6 July 2018

1 reference

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Continuous delta-opioid receptor activation reduces neuronal voltage-gated sodium channel (NaV1.7) levels through activation of protein kinase C in painful diabetic neuropathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Nav1.7 expression is increased in painful human dental pulp

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Tetrodotoxin for Moderate to Severe Cancer Pain: A Randomized, Double Blind, Parallel Design Multicenter Study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

From genes to pain: Na v 1.7 and human pain disorders

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Changes in the expression of NaV1.7, NaV1.8 and NaV1.9 in a distinct population of dorsal root ganglia innervating the rat knee joint in a model of chronic inflammatory joint pain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

An open-label, multi-dose efficacy and safety study of intramuscular tetrodotoxin in patients with severe cancer-related pain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Sodium channel Nav1.6 accumulates at the site of infraorbital nerve injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Voltage-gated ion channels and gating modifier toxins.

6 July 2018

1 reference

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An SCN9A channelopathy causes congenital inability to experience pain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.

6 July 2018

1 reference

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Sodium channel expression in the ventral posterolateral nucleus of the thalamus after peripheral nerve injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Upregulation of persistent and ramp sodium current in dorsal horn neurons after spinal cord injury.

6 July 2018

1 reference

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International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

6 July 2018

1 reference

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Behavioral changes and trigeminal ganglion sodium channel regulation in an orofacial neuropathic pain model

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

The primary periodic paralyses: diagnosis, pathogenesis and treatment

6 July 2018

1 reference

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Sodium channel inactivation: molecular determinants and modulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine

6 July 2018

1 reference

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Neuropathic pain: early spontaneous afferent activity is the trigger

6 July 2018

1 reference

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Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Human surrogate models of neuropathic pain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Contactin associates with sodium channel Nav1.3 in native tissues and increases channel density at the cell surface

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Early painful diabetic neuropathy is associated with differential changes in tetrodotoxin-sensitive and -resistant sodium channels in dorsal root ganglion neurons in the rat.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Upregulation of Sodium Channel Nav1.3 and Functional Involvement in Neuronal Hyperexcitability Associated with Central Neuropathic Pain after Spinal Cord Injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Overview of the voltage-gated sodium channel family

6 July 2018

1 reference

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Accumulation of PN1 and PN3 sodium channels in painful human neuroma-evidence from immunocytochemistry

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Animal models of nociception.

6 July 2018

1 reference

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The changes in expression of three subtypes of TTX sensitive sodium channels in sensory neurons after spinal nerve ligation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Transcriptional channelopathies: an emerging class of disorders

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Nav1.3 sodium channels: rapid repriming and slow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Plasticity of TTX-sensitive sodium channels PN1 and brain III in injured human nerves

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Glial-derived neurotrophic factor upregulates expression of functional SNS and NaN sodium channels and their currents in axotomized dorsal root ganglion neurons.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Differential distribution of the tetrodotoxin-sensitive rPN4/NaCh6/Scn8a sodium channel in the nervous system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Upregulation of a silent sodium channel after peripheral, but not central, nerve injury in DRG neurons.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Tetrodotoxin: anesthetic activity in the de-epithelialized cornea

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

A novel tetrodotoxin-sensitive, voltage-gated sodium channel expressed in rat and human dorsal root ganglia.

6 July 2018

1 reference

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Selective loss of slow and enhancement of fast Na+ currents in cutaneous afferent dorsal root ganglion neurones following axotomy.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Down-regulation of transcripts for Na channel alpha-SNS in spinal sensory neurons following axotomy

6 July 2018

1 reference

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Sodium channel expression: a dynamic process in neurons and non-neuronal cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is reexpressed following axotomy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Primary structure and functional expression of a mammalian skeletal muscle sodium channel

6 July 2018

1 reference

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Ion channels in spinal cord astrocytes in vitro. II. Biophysical and pharmacological analysis of two Na+ current types

6 July 2018

1 reference

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Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain.

6 July 2018

1 reference

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Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Distribution of the voltage gated sodium channel Na(v)1.3-like immunoreactivity in the adult rat central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Changes in expression of voltage-dependent ion channel subunits in dorsal root ganglia of rats with radicular injury and pain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Varicella zoster virus induces neuropathic changes in rat dorsal root ganglia and behavioral reflex sensitisation that is attenuated by gabapentin or sodium channel blocking drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Relationship between sodium channel NaV1.3 expression and neuropathic pain behavior in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

TNF-α contributes to up-regulation of Nav1.3 and Nav1.8 in DRG neurons following motor fiber injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Altered sodium channel expression in second-order spinal sensory neurons contributes to pain after peripheral nerve injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Sodium channel Na(v)1.6 is expressed along nonmyelinated axons and it contributes to conduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Changes in three subtypes of tetrodotoxin sensitive sodium channel expression in the axotomized dorsal root ganglion in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Autotomy behavior correlates with the DRG and spinal expression of sodium channels in inbred mouse strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Characterization of a familial case with primary erythromelalgia from Taiwan.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Two novel SCN9A mutations causing insensitivity to pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Ibuprofen blocks changes in Na v 1.7 and 1.8 sodium channels associated with complete Freund's adjuvant-induced inflammation in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Decrease in inflammatory hyperalgesia by herpes vector-mediated knockdown of Nav1.7 sodium channels in primary afferents

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Nav1.7 accumulates and co-localizes with phosphorylated ERK1/2 within transected axons in early experimental neuromas.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Experimental study of tetrodotoxin, a long-acting topical anesthetic

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Sensory fibers resistant to the actions of tetrodotoxin mediate nocifensive responses to local administration of endothelin-1 in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Site 1 sodium channel blockers prolong the duration of sciatic nerve blockade from tricyclic antidepressants

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Antinociceptive effects of tetrodotoxin (TTX) in rodents.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Tetrodotoxin inhibits the development and expression of neuropathic pain induced by paclitaxel in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Sigma-1 receptors are essential for capsaicin-induced mechanical hypersensitivity: studies with selective sigma-1 ligands and sigma-1 knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Differential anti-neuropathic pain effects of tetrodotoxin in sciatic nerve- versus infraorbital nerve-ligated rats--behavioral, pharmacological and immunohistochemical investigations

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Antinociceptive action of carbamazepine on thermal hypersensitive pain at spinal level in a rat model of adjuvant-induced chronic inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 1): hyperalgesia, edema, and systemic cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Subcutaneous tetrodotoxin and inflammatory pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Sodium channels contribute to microglia/macrophage activation and function in EAE and MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Low dose of tetrodotoxin reduces neuropathic pain behaviors in an animal model.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Effects of pre-emptive drug treatment on astrocyte activation in the cuneate nucleus following rat median nerve injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Vincristine-induced allodynia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Tetrodotoxin inhibits neuropathic ectopic activity in neuromas, dorsal root ganglia and dorsal horn neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Ion channels associated with the ectopic discharges generated after segmental spinal nerve injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Focal Lysolecithin-Induced Demyelination of Peripheral Afferents Results in Neuropathic Pain Behavior That Is Attenuated by Cannabinoids

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Membrane potential oscillations in dorsal root ganglion neurons: role in normal electrogenesis and neuropathic pain.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Downregulation of tetrodotoxin-resistant sodium currents and upregulation of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons after nerve injury.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Astrocyte Na+ channels are required for maintenance of Na+/K(+)-ATPase activity.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3296997

Transcriptional and functional profiles of voltage-gated Na+ channels in injured and non-injured DRG neurons in the SNI model of neuropathic pain

28 October 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD10020281

Altered expression of sodium channel distribution in the dorsal root ganglion after gradual elongation of rat sciatic nerves

21 January 2018

1 reference

12 December 2020

Hyperexcitability at sites of nerve injury depends on voltage-sensitive Na+ channels

1 reference

12 December 2020

Voltage-gated ion channel Nav1.7 innervation in patients with idiopathic rectal hypersensitivity and paroxysmal extreme pain disorder (familial rectal pain)

1 reference

12 December 2020

A possible role for nerve growth factor in the augmentation of sodium channels in models of chronic pain

1 reference

12 December 2020

Chemotherapy-induced peripheral neurotoxicity

1 reference

12 December 2020

Voltage-gated sodium channel expression in rat and human epidermal keratinocytes: evidence for a role in pain

1 reference

12 December 2020

Changes of sodium channel expression in experimental painful diabetic neuropathy

1 reference

12 December 2020

Ion channels in glial cells

1 reference

12 December 2020

Re-evaluation of the phenotypic changes in L4 dorsal root ganglion neurons after L5 spinal nerve ligation

1 reference

12 December 2020

Changes in electrophysiological properties and sodium channel Nav1.3 expression in thalamic neurons after spinal cord injury

1 reference

12 December 2020

Laminae-specific distribution of alpha-subunits of voltage-gated sodium channels in the adult rat spinal cord

1 reference

12 December 2020

Changes in sodium channel expression following trigeminal nerve injury

1 reference

12 December 2020

Identifiers

DOI

10.3390/MD10020281

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412801%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412801%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22412801%20AND%20SRC:MED&resulttype=core&format=json