Clinical gene therapy in hematology: past and future (Q34261291)

1 August 2017

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title

Clinical gene therapy in hematology: past and future (English)

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1 August 2017

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Richter J

1

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1 August 2017

Karlsson S

series ordinal

2

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1 August 2017

publication date

1 February 2001

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International Journal of Hematology

1 August 2017

published in

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1 August 2017

volume

73

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1 August 2017

issue

2

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1 August 2017

page(s)

162-169

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Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection

1 August 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FBF02981933

Retroviral gene transduction of adult peripheral blood or marrow-derived CD34+ cells for six hours without growth factors or on autologous stroma does not improve marking efficiency assessed in vivo

21 January 2018

1 reference

12 December 2020

Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells

1 reference

12 December 2020

A murine leukemia virus (MuLV) long terminal repeat derived from rhesus macaques in the context of a lentivirus vector and MuLV gag sequence results in high-level gene expression in human T lymphocytes

1 reference

12 December 2020

Stable integration of human immunodeficiency virus-based retroviral vectors into the chromosomes of nondividing cells

1 reference

12 December 2020

Prolonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous disease

1 reference

12 December 2020

The use of granulocyte colony-stimulating factor during retroviral transduction on fibronectin fragment CH-296 enhances gene transfer into hematopoietic repopulating cells in dogs

1 reference

12 December 2020

Transduction of nondividing cells using pseudotyped defective high-titer HIV type 1 particles

1 reference

12 December 2020

Engraftment of hematopoietic progenitor cells transduced with the Fanconi anemia group C gene (FANCC)

1 reference

12 December 2020

Gene transfer to hematopoietic cells--the clinical experience.

1 reference

12 December 2020

Development of a novel selective amplifier gene for controllable expansion of transduced hematopoietic cells

1 reference

12 December 2020

Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: implications for gene therapy

1 reference

12 December 2020

Human growth factor-enhanced regeneration of transplantable human hematopoietic stem cells in nonobese diabetic/severe combined immunodeficient mice

1 reference

12 December 2020

Progress in gene therapy for chronic granulomatous disease

1 reference

12 December 2020

Transduction of human progenitor hematopoietic stem cells by human immunodeficiency virus type 1-based vectors is cell cycle dependent.

1 reference

12 December 2020

Distinct requirements for optimal growth and In vitro expansion of human CD34(+)CD38(-) bone marrow long-term culture-initiating cells (LTC-IC), extended LTC-IC, and murine in vivo long-term reconstituting stem cells.

1 reference

12 December 2020

Direct demonstration that autologous bone marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells.

1 reference

12 December 2020

Stable transduction of quiescent CD34(+)CD38(-) human hematopoietic cells by HIV-1-based lentiviral vectors

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12 December 2020

Engraftment of MDR1 and NeoR gene-transduced hematopoietic cells after breast cancer chemotherapy

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12 December 2020

Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector

1 reference

12 December 2020

Retroviral-mediated gene transfer into CD34-enriched human peripheral blood stem cells.

1 reference

12 December 2020

The level of mRNA encoding the amphotropic retrovirus receptor in mouse and human hematopoietic stem cells is low and correlates with the efficiency of retrovirus transduction

1 reference

12 December 2020

HIV, but not murine leukemia virus, vectors mediate high efficiency gene transfer into freshly isolated G0/G1 human hematopoietic stem cells

1 reference

12 December 2020

Genetic marking shows that Ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow in CML.

1 reference

12 December 2020

T lymphocyte-directed gene therapy for ADA- SCID: initial trial results after 4 years.

1 reference

12 December 2020

Highly efficient transduction of the green fluorescent protein gene in human umbilical cord blood stem cells capable of cobblestone formation in long-term cultures and multilineage engraftment of immunodeficient mice.

1 reference

12 December 2020

Improved gene transfer into baboon marrow repopulating cells using recombinant human fibronectin fragment CH-296 in combination with interleukin-6, stem cell factor, FLT-3 ligand, and megakaryocyte growth and development factor

1 reference

12 December 2020

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

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12 December 2020

In vivo selection of retrovirally transduced hematopoietic stem cells

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12 December 2020

Characterization of membrane components of the erythrocyte involved in vesicular stomatitis virus attachment and fusion at acidic pH.

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12 December 2020

The basic science of gene therapy

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12 December 2020

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells

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12 December 2020

Efficient transduction of human lymphocytes and CD34+ cells via human immunodeficiency virus-based gene transfer vectors.

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12 December 2020

Thrombopoietin, kit ligand, and flk2/flt3 ligand together induce increased numbers of primitive hematopoietic progenitors from human CD34+Thy-1+Lin- cells with preserved ability to engraft SCID-hu bone

1 reference

12 December 2020

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

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12 December 2020

Human immunodeficiency virus type 1 vectors efficiently transduce human hematopoietic stem cells

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12 December 2020

Efficient and durable gene marking of hematopoietic progenitor cells in nonhuman primates after nonablative conditioning

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12 December 2020

Self-renewal of primitive human hematopoietic cells (long-term-culture-initiating cells) in vitro and their expansion in defined medium

1 reference

12 December 2020

Gene transfer into marrow repopulating cells: comparison between amphotropic and gibbon ape leukemia virus pseudotyped retroviral vectors in a competitive repopulation assay in baboons.

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12 December 2020

T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates.

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12 December 2020

A packaging cell line for lentivirus vectors.

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12 December 2020

Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency

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12 December 2020

Expansion of human NOD/SCID-repopulating cells by stem cell factor, Flk2/Flt3 ligand, thrombopoietin, IL-6, and soluble IL-6 receptor

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12 December 2020

Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients

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12 December 2020

Results of MDR-1 vector modification trial indicate that granulocyte/macrophage colony-forming unit cells do not contribute to posttransplant hematopoietic recovery following intensive systemic therapy

1 reference

12 December 2020

Gene therapy in peripheral blood lymphocytes and bone marrow for ADA- immunodeficient patients

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12 December 2020

Ex vivo expansion of genetically marked rhesus peripheral blood progenitor cells results in diminished long-term repopulating ability

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12 December 2020

Gene therapy for haematopoietic and lymphoid disorders.

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12 December 2020

A third-generation lentivirus vector with a conditional packaging system

1 reference

12 December 2020

Retroviral transfer of the glucocerebrosidase gene into CD34+ cells from patients with Gaucher disease: in vivo detection of transduced cells without myeloablation

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12 December 2020

Retrovirally marked CD34-enriched peripheral blood and bone marrow cells contribute to long-term engraftment after autologous transplantation

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12 December 2020

Expansion of genetically modified primary human hemopoietic cells using chemical inducers of dimerization

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12 December 2020

Viral vectors for gene therapy of hematopoietic cells

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12 December 2020

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

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12 December 2020

Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus

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12 December 2020

Gene-marking to trace origin of relapse after autologous bone-marrow transplantation.

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12 December 2020

Feasibility of multidrug resistance (MDR-1) gene transfer in patients undergoing high-dose therapy and peripheral blood stem cell transplantation for lymphoma

1 reference

12 December 2020

Efficient retroviral-mediated gene transfer to human cord blood stem cells with in vivo repopulating potential

1 reference

12 December 2020

Gene transfer approaches to the lysosomal storage disorders

1 reference

12 December 2020

High-efficiency gene transfer into CD34+ cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G.

1 reference

12 December 2020

Retroviral gene transfer to primitive normal and leukemic hematopoietic cells using clinically applicable procedures

1 reference

12 December 2020

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12 December 2020

Chemotherapy immediately following autologous stem-cell transplantation in patients with advanced breast cancer

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12 December 2020

Development of a modified selective amplifier gene for hematopoietic stem cell gene therapy

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12 December 2020

Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retrovirus containing the multidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients

1 reference

12 December 2020

Phase I trial of retroviral-mediated transfer of the human MDR1 gene as marrow chemoprotection in patients undergoing high-dose chemotherapy and autologous stem-cell transplantation.

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12 December 2020

Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo SCID-repopulating cell assay

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12 December 2020

Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors

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12 December 2020

Identifiers

DOI

10.1007/BF02981933

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Dimensions Publication ID

1 August 2017

1026732959

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